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20 May 2011, Volume 38 Issue 3 Previous Issue    Next Issue

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Concept of minimally invasive extraction and technical operations HU Kai-jin, YANG Qing-tian. Inter J Stomatol. 2011, 38 (3):  249-252.  DOI: 10.3969/j.issn.1673-5749.2011.03.001 Abstract ( 1511 )   HTML ( 20 )   PDF（pc） (274KB) ( 1943 )   Save With the advances in technology, development of medical science and the introduction of new extraction instruments, the concepts and techniques of minimally invasive in tooth extraction emerged and developed. In China, however, the concept and technology has not been widely promoted and applied currently, far below patients and doctors’needs. In our article, we will introduce the concepts and techniques of minimally invasive in tooth extraction in detail by using the removal of complicated teeth and impacted teeth for example. We hope that could help to promote and spread the concepts and techniques of minimally invasive in tooth extraction. Related Articles | Metrics

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Osteoprotegerin and Wnt-1 express in tension side of periodontal tissue QIN Ming-qun, XU Lian-jing, XU Yang. Inter J Stomatol. 2011, 38 (3):  253-256.  DOI: 10.3969/j.issn.1673-5749.2011.03.002 Abstract ( 1054 )   HTML ( 2 )   PDF（pc） (282KB) ( 632 )   Save Objective Using immunohistochemistry and RT-PCR two detection methods, We aimed to investigate the changes of osteoprotegerin（OPG） and Wnt-1 expression in tension side by periodontal tissue during orthodontic tooth movement in rats and detect the relationship between OPG, Wnt-1 and orthodontic periodontal tissue remodelling. Methods Orthodontic tooth movement model of 80 merely rats was prepared, and at the 1, 3, 5, 7 d after tooth movement the teeth were extracted respectively. The hematoxylin-eosin staining of rats tension side of the morphology of periodontal tissue was observed, and the RT-PCR and immunohistochemical method was used to detect Wnt-1 and OPG expression in tension side periodontal tissue. Results The expression of OPG were weak in normal periodontal tissue. In tension area, OPG expression increased in 3 days, then reached the maximum at day 5, and new bone formation could be seen at that time; on day 7, OPG expression declined. There was no Wnt-1 expression in RT-PCR, but on day 3, 5, Wnt-1 expression positive cells of the periodontal ligament cell in immunohistochemical method. Conclusion OPG participated in the process of orthodontic periodontal tissue rebuilding, and the OPG expression increased in tension area in a time -dependent manner; the correlation of Wnt-1 with orthodontic periodontal tissue reconstruction is not certain, need to be studied further. Related Articles | Metrics

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Effects of nano-silica coating on fracture strength of glass infiltrated alumina ceramic ZHU Ye1, XIE Hai-feng2, ZHANG Fei-min2. Inter J Stomatol. 2011, 38 (3):  257-260.  DOI: 10.3969/j.issn.1673-5749.2011.03.003 Abstract ( 928 )   HTML ( 3 )   PDF（pc） (399KB) ( 833 )   Save Objective The aim of this study was to evaluate the effects of nano -silica coating prepared by different concentration silica sol on fracture strength of glass infiltrated alumina ceramic after bonding. Methods Five In-Ceram alumina ceramic groups were fabricated to receive different surface treatments as group A, B, C, D, E. Each ceramic disc was bonded to dentin with dual -cured resin cement, and then fracture strength of these samples was tested. After one sample of each group as before, scanning electron microscopy and energy dispersive spectrometer was used to analyze the interface. Results There existed differences among the five groups（P<0.05）, group C, D, E were higher than group A and B. There was not only no difference between group A and B, but also among group C, D, E. Small crack was detected in the interface of group A and B, but was not existed in group C, D, E. Conclusion A higher fracture strength could be acquired through preparing silica coating with sol-gol process on sandblasted In-Ceram ceramic surface followed by application of silane. But no difference is existed among the groups prepared by different concentration silica sol. Related Articles | Metrics

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In vitro study of furcal perforation repaired with cobalt-chrome alloy inlays WANG Mi, YIN Shi -hai, TANG Yin, LIU Jia. Inter J Stomatol. 2011, 38 (3):  261-264.  DOI: 10.3969/j.issn.1673-5749.2011.03.004 Abstract ( 1059 )   HTML ( 4 )   PDF（pc） (337KB) ( 701 )   Save Objective To evaluate the effect of furcal perforation treated with cobalt-chrome alloy inlays, including both morphologic and microleakage study. Methods 42 newly extracted human maxillary and mandibular molars were collected. 38 of them, perforations were made in the center of the pulp chamber floor by using the 8 high speed round bur, divided randomly into two experimental groups. The other intact 4 sample were used as the negative controls. In the experimental groups, group A were repaired by cobalt -chrome alloy inlays, group B were repaired by indirect composite inlay. Resin reinforced glass ionomer was used in all samples as cement. 4 of each group were evaluated under scanning electron microscope（SEM）, and microleakage of others was measured by the concentration of leaked glucose with the oxidase-peroxidase method. Results Microleakage of group A was higher than group B, but no statistical difference（P>0.05）. The two groups had reached a good furcation shape. The gap width of group A was less than B group by SEM. Conclusion For repairing furcal perforation, the method of cobalt-chrome alloy inlay is as good as that of indirect composite inlay. Related Articles | Metrics

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Efficacy evaluation of immediate dentin sealing for prevention of dentin hypersensitivity after porcelain veneer restoration SUN Xue-wu, HAO Peng-jie, XIAO Li-jing. Inter J Stomatol. 2011, 38 (3):  265-267.  DOI: 10.3969/j.issn.1673-5749.2011.03.005 Abstract ( 1364 )   HTML ( 8 )   PDF（pc） (114KB) ( 839 )   Save Objective To evaluate the effect of immediate dentin sealing in the prevention of dentin hypersensitivity after porcelain veneer restoration. Methods 76 patients with 138 upper anterior teeth in different patients were randomly divided into two groups, namely experiment group（69 teeth） of dentin bonding agent（single bond Ⅱ） coating the preparational surface of abutment and light-cured following preparation before making the impression, control group（69 teeth） of making the impression after preparation directly. After the removal of the temporary veneer, sensitive evaluation of labial surface of abutment 24 hours, one week later, and one month later before the veneer restoration finished was conducted. Results There are significant differences between experiment group and control group in 1 degree and in 2 degrees when evaluated prepared 24 hours and one week later. There is significant difference between experiment group and control group in 0 degree and 2 degrees when evaluated prepared one month later. Conclusion The effect of dentin bonding agent in the prevention of dentin hypersensitivity after porcelain veneer restoration are significant. In our clinical trail, coating the preparational surface of abutment and light-cured following preparation before making the impression can reduce the abutment hypersensitivity and shorten the time of patients who adapt to the dentures. Related Articles | Metrics

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Ginkgolic acids can enhance the drug-sensitivity of Tca8113 DAI Li-na, SU Qin, ZHOU Chen-chen, WANG Hui, CHEN Jiao, ZHANG Ping. Inter J Stomatol. 2011, 38 (3):  268-273.  DOI: 10.3969/j.issn.1673-5749.2011.03.006 Abstract ( 1042 )   HTML ( 4 )   PDF（pc） (584KB) ( 791 )   Save Objective To investigate the effect and mechanism of ginkgolic acid（GA） on drug -sensitivity of Tca8113 cells to chemotherapy drug. Methods Methyl thiazolyl tetrazolium（MTT） assay for detection of single use of Carboplatin（CBP） or Paclitaxel（PTX） and combination of CBP or PTX with GA on Tca8113 cell survival rate. Western blot detection of protein expression of p-protein kinase D（PkD）-2 and PkD-2 in Tca8113 cell induced by GA with different times, shRNA was introduced to downregulate the expression of PkD-2 in Tca8113 cell line. The proliferation activity and programmed cell death rate of shRNA mediated Tca8113 cells were detected by MTT and flow cytometry respectively. Results The drug-sensitivity of Tca8113 cells was enhanced by GA significantly; the expression of p-PkD-2 protein in Tca8113 cells was inhibited by GA in a time-dependent manner vs PkD-2, compared to the control, shRNA targeting of PkD-2 leads to the efficient and specific silence of pkD-2 mRNA and protein expression as determined by RT-PCR and Western blot, a dramatic reduction of cell proliferation and an increased programmed cell death rate of Tca8113 cells treated with chemotherapy drug in vitro. Conclusion GA can induce Tca8113 cells programmed cell death by inhibiting the phosphorylation of p- PkD-2，thus enhance the sensitivity of Tca8113 cells to chemotherapy drug. Related Articles | Metrics

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Evaluate color change of discolored tooth after restored with IPS-EMPRESS Ⅱ ceramics QIAN Hai-xin, ZHANG Xiu-yin, YANG Dan-ling. Inter J Stomatol. 2011, 38 (3):  274-276.  DOI: 10.3969/j.issn.1673-5749.2011.03.007 Abstract ( 1312 )   HTML ( 6 )   PDF（pc） (135KB) ( 739 )   Save Objective The objective of this study was to evaluate the color change of discolored tooth after restored with IPS-EMPRESS Ⅱ ceramics. Methods 30 anterior tetracycline teeth were veneered and 30 anterior discolored teeth after root canal treatment were restored with full crowns. The ShadeEye-NCC color system was used to analyze the change in L, a and b. Then the chromatism[（ΔEab=（ΔL2+Δa2+Δb2）1/2）] as well as the value of Lab （ Lab=L）, Cab[（Cab=（a2+b2）1/2）] and Hab[（Hab=arctan（b/a）] were calculated. Results After veneered and crowned the teeth’s color had obviously changed. Additionally, there were some color changes of 60 teeth between before and after bonding. The average chromatism of the veneered teeth reached 2.37, and the Lab, Cab and Hab had statistical differences（P<0.05）. The average chromatism of the crowned teeth reached 1.36, and the Hab had statistical differences（P<0.05）. Conclusion The IPS-EMPRESS Ⅱ ceramics can effectively improve the color of discolored tooth. An appropriate bonding agent should be chosen to perfect the final results of the veneered tooth. Related Articles | Metrics

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Clinical observation of curative effect of Vitapex paste in the process of changing drugs for chronic infectious wound in face HE Li-hua Inter J Stomatol. 2011, 38 (3):  277-278.  DOI: 10.3969/j.issn.1673-5749.2011.03.008 Abstract ( 1193 )   HTML ( 3 )   PDF（pc） (77KB) ( 602 )   Save Objective To relieve pain caused by gauze conglutinating to the wound, and to reduce rebleeding and shorten the healing time. Methods 53 outpatients were randomly divided into experimental group and the reference group. After finishing debridement and disinfection, change drugs with Vitapex paste for the wound of the experimental group until healed. After finishing debridement and disinfection, change drugs with conventional paste for the wound of the reference group until healed. Results The experimental group lost less time and got a better effect than the reference group. Conclusion Changing drugs for the infectious wound with Vitapex paste has more significant effect, such as wound healing quickly, and less pain when changing drugs for wound. Related Articles | Metrics

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The charactristics of speech training for postoperation cleft palate patients who have marginal velopharyngeal insufficiency after palatoplasty CHEN Xiao-rong1, ZHAO Biao1, YIN Heng2. Inter J Stomatol. 2011, 38 (3):  279-282.  DOI: 10.3969/j.issn.1673-5749.2011.03.009 Abstract ( 1028 )   HTML ( 2 )   PDF（pc） (149KB) ( 754 )   Save Objective The intent of the research is to probe the methods and feasibilities of speech therapy to those patients who have marginal velophargngeal insufficiency after operation. Methods By means of research of samples, 15 patients with language handicaps suffered from concrete phonemic problems and sifuafims of velopharygneal closure were selected to take the pronunciation training according to their distinct pronunciation problems. Results The research results demonstrated that each patient can articulate consonant accurately and degree of clarity of pronunciation had increased from 49.53% to 95.38% on average. Conclusion Patients with language handicaps suffered from concrete phonemic problems and sifuafims of velopharygneal closure, through addressed training, reinforce the muscle of soft palate, collect the undesirable habit of pronunciation. They finally master the articulation skill and achieve a normal level of articulation. Related Articles | Metrics

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Cost-effectiveness analysis of two kinds of porcelain fused-to-metal restoration HU Rong, ZHANG Min. Inter J Stomatol. 2011, 38 (3):  283-285.  DOI: 10.3969/j.issn.1673-5749.2011.03.010 Abstract ( 996 )   HTML ( 1 )   PDF（pc） (113KB) ( 672 )   Save Objective To determine the effects, in economic aspect of clinical effects by porcelain fused-to-metal restoration made from Ni-Cr alloy or precious alloy during tooth defect or denture defect therapy. Methods A search for the objective articles was performed from the following database: CNKI, CBM and VP. RevMan software was applied to conduct meta-analysis. The clinical effects and economical analysis were studied. Results Twelve articles met the final selection criteria. The significant differences were found in the marginal color, gingivitis, damage, marginal fit the C/E of the precious alloy group was respectively 1 645.38 yuan, 1 588.79 yuan, 1 524.79 yuan, 2 201.95 yuan more than that of the Ni-Cr alloy group. Conclusion In clinical effects and biological safety aspect, the precious alloy is superior to Ni-Cr alloy. However, in economical aspect, the Ni-Cr alloy is to superior previous alloy. Related Articles | Metrics

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Micro implant anchorage clinical success in orthodontic treatment of deeply impacted mandibular molar YANG Hong1, XIE De-lin2. Inter J Stomatol. 2011, 38 (3):  286-287.  DOI: 10.3969/j.issn.1673-5749.2011.03.011 Abstract ( 1033 )   HTML ( 2 )   PDF（pc） (584KB) ( 796 )   Save Impaction of both first permanent molar and second permanent molar in lower mandible is rarely. Treatments depend on the degree of molar inclination, the position of first molar and second molar, the classification of bite（Angle’s Ⅰ classification）, the position and the appearance of third molar. A case of successful uprighting a severely impacted right mandibular first molar using a micro implant anchorage, fixed appliance and oral surgical procedures is presented. Methods include surgical extraction of an impacted second molar and acceptable mesial movement of third molar which would move to the position of second molar. Related Articles | Metrics

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Research progress on reduction of bone resorption through alveolar ridge preservation after tooth extraction ZHANG Yong, LI Yun-sheng. Inter J Stomatol. 2011, 38 (3):  288-291.  DOI: 10.3969/j.issn.1673-5749.2011.03.012 Abstract ( 1239 )   HTML ( 8 )   PDF（pc） (129KB) ( 1595 )   Save Implant therapy has become a widely recognized treatment alternative for replacing missing teeth. While successful implant therapy requires sufficient alveolar bone volume and favorable ridge architecture. After tooth extraction, dimensional changes of the alveolar ridge often occur due to bone resorption. These changes are usually clinically significant and can complicate restorations with implant or conventional prostheses. Preservation of alveolar dimension can minimize residual ridge resorption and can be essential to maintain adequate bone volume, thus be crucial to achieve optimal esthetic and functional prosthodontic results. This article reviewed the literature, presents socket preservation techniques, atraumatic tooth extraction, healing pattern of socket after tooth extraction as well as the use of bone grafting materials and barrier membranes. Related Articles | Metrics

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Research progress on dental pulp regeneration LEI Gang, ZHANG Guang-dong, YU Jin-hua. Inter J Stomatol. 2011, 38 (3):  292-296.  DOI: 10.3969/j.issn.1673-5749.2011.03.013 Abstract ( 1263 )   HTML ( 13 )   PDF（pc） (166KB) ( 2429 )   Save Although current root canal therapy offers a high success rate for many teeth with pulp diseases, there are still many post-treatment complications. Due to the development of life science such as molecular biology, cell biology, and developmental biology, it is possible that the pulp treatment approaches change from traditional obturation therapy to biological treatment. This review presents recent progresses in dental pulp reconstruction, including odontoblast regeneration, pulp revascularization, never regeneration and scaffold implantation. Related Articles | Metrics

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Two-component signal transduction system and the virulence-related characteristics of Streptococcus mutans CHEN Jiao, ZHOU Zhi, JIANG Dan. Inter J Stomatol. 2011, 38 (3):  297-300.  DOI: 10.3969/j.issn.1673-5749.2011.03.014 Abstract ( 1069 )   HTML ( 3 )   PDF（pc） (149KB) ( 1053 )   Save Two-component signal transduction system（TCSTS） plays an important role in the expression of virulence factors of Streptococcus mutans, such as the competence development, the formation of biofilm, the stability of structure, the production of bacteriocin, and the properties of acid production and resistance. It provides many ecological advantages to compete and survive in the dental plaque. This article is a review about the composition of TCSTS of Streptococcus mutans, the effect of TCSTS on the virulence-related characteristics of Streptococcus mutans, and the application significance of TCSTS. Related Articles | Metrics

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Role of nanobacteria in oral disease and other systemic disease MO Li-ji, CHEN Wen-xia. Inter J Stomatol. 2011, 38 (3):  301-303.  DOI: 10.3969/j.issn.1673-5749.2011.03.015 Abstract ( 1123 )   HTML ( 2 )   PDF（pc） (143KB) ( 561 )   Save Nanobacteria are the smallest known bacteria, and the adamant shells they form have relations with pathologic calcification. About its “living organism”, a great deal of controversy has raised within the scientific community in recent years. There have been evidences that abundance of nanobacteria in the oral cavity such as saliva, the surface of the teeth, dental plaque, calculus dentalis, pulp stone and so on. This article reviews nanobacteria and its role in oral disease and other systemic disease. Related Articles | Metrics

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Formation mechanism of Enterococcus faecalis biofilm associating with post-treatment endodontic disease WEN Chun -mei, CHEN Wen -xia. Inter J Stomatol. 2011, 38 (3):  304-307.  DOI: 10.3969/j.issn.1673-5749.2011.03.016 Abstract ( 1095 )   HTML ( 2 )   PDF（pc） (159KB) ( 798 )   Save Enterococcus faecalis biofilm continuously releases pathogenic factors to the root apical region, causing post-treatment endodontic disease. Effective control of the formation of Enterococcus faecalis biofilm is the key to higher success rate of root canal therapy. This article reviewed the structure and biological characteristics of Enterococcus faecalis in root canal, and the cohesion and environment factors affecting the biofilm formation. Related Articles | Metrics

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Role of high mobility group box-1 in the migration of adult stem cells ZHANG Xu-fang, LING Jun-qi. Inter J Stomatol. 2011, 38 (3):  308-311.  DOI: 10.3969/j.issn.1673-5749.2011.03.017 Abstract ( 991 )   HTML ( 2 )   PDF（pc） (146KB) ( 783 )   Save High mobility group box-1（HMGB1） is a ubiquitous and highly-conserved nuclear protein within all eukaryotic cells, and it can be released into extracellular space during tissue damage or stress state. Apart from playing a role of inflammatory cytokine in immune response, HMGB1 could also mediate migration of adult stem cells, promoting repair and regeneration of various tissues. This review focuses on the structure and biochemistry features of HMGB1 and receptor for advanced glycation end product（RAGE）, and their effect on adult stem cells migration as well as signal transduction pathway, providing a new clue for migration of dental pulp stem cells and restoration of damaged dental pulp. Related Articles | Metrics

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Biological characteristics of special AT-rich sequence bingding protein-2 CHEN Xiao-xia1, SUN Qin-feng1,2. Inter J Stomatol. 2011, 38 (3):  312-314.  DOI: 10.3969/j.issn.1673-5749.2011.03.018 Abstract ( 1201 )   HTML ( 1 )   PDF（pc） (119KB) ( 943 )   Save Special AT-rich sequence binding protein（SATB）-2 is a nuclear matrix protein, which plays an important role in the craniofacial growth and differentiation of osteoblasts. The biological characteristics, functions and the prospects in periodontal therapy of SATB-2 are summarized in this paper. Related Articles | Metrics

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Mutacins related to quorum sensing system and the analysis of their functions HUO Yong-biao, LING Junqi. Inter J Stomatol. 2011, 38 (3):  315-318.  DOI: 10.3969/j.issn.1673-5749.2011.03.019 Abstract ( 957 )   HTML ( 1 )   PDF（pc） (174KB) ( 704 )   Save Bacteriocins are antibacterial proteins or polypeptides directly produced by some bacteria during their metabolic process. Streptococcus mutants also produce bacteriocin which named mutacin. Mutacins are probably relevant to the cariogenic characters and colonization of the Streptococcus mutants. Researchers pay close attention to the potential application on new antimicrobial by studying about mutacins. Many mutacins have been isolated and purified, some of which are related to quorum sensing regulation system. Furthermore, the gene sequences and amino acid sequences of these mutacins are also determined. This review summarizes the function of mutacins that related to the quorum sensing system. Related Articles | Metrics

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Cell-cell interactions in tooth development WU Yu, ZHOU Xue-dong. Inter J Stomatol. 2011, 38 (3):  319-322.  DOI: 10.3969/j.issn.1673-5749.2011.03.020 Abstract ( 1105 )   HTML ( 3 )   PDF（pc） (138KB) ( 812 )   Save Tooth development involves a series of interactions between the oral epithelium and cranial neural crest-derived mesenchymal cells. These interactions progressively transform the tooth primordia into complex mineralized structures. Cell-cell interactions play complementary roles in allowing plasticity during tooth morphogenesis and stabilization at later stages of epithelial histogenesis. This article reviews the role of cell-cell interactions mediated by adherens junctions formed by cadherins and communicative gap junctions formed by connexins in regulating tooth development. Related Articles | Metrics

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Fracture mechanics of enamel and dentin ZHONG Lin, YU Hai-yang. Inter J Stomatol. 2011, 38 (3):  323-325.  DOI: 10.3969/j.issn.1673-5749.2011.03.021 Abstract ( 1109 )   HTML ( 7 )   PDF（pc） (108KB) ( 615 )   Save Tooth fracture reduced mastication efficiency of patients, therefore, it is necessary to understand the crack propagation behavior of tooth. Studying the fracture toughness and fatigue crack growth behavior of enamel and dentin using fracture mechanics is also important for preventing various disease of tooth and developing materials for restorative dentistry. In this article, the fracture behaviors of dentin and enamel were reviewed. Related Articles | Metrics

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Educational status of the oral implantology in developed countries GUO Da -wei1，2, LIANG Xing1, CHEN Yue1. Inter J Stomatol. 2011, 38 (3):  326-328.  DOI: 10.3969/j.issn.1673-5749.2011.03.022 Abstract ( 919 )   HTML ( 3 )   PDF（pc） (131KB) ( 630 )   Save Oral implantology is a subject concerning the implantation of the oral hard and soft tissue to reconstruct the defects. Recently, in the field of the oral implantology, with the advance of the research and the rapid development of the dental implant system, dental implatation has been widely used in clinic, and the need of the implant therapy is increasing. In order to meet these needs, many dental schools in developed countries further enhance undergraduate education in oral implantology, in addition, they also carry out a variety of different types of postgraduate education courses. Now, oral implantology education in developed countries has formed a flexible multi- level teaching system. Related Articles | Metrics

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Research progress on demineralized osteoinduction of deminerlized dentin matrix BAO Ji-bo, XIE Zhi-gang. Inter J Stomatol. 2011, 38 (3):  329-331.  DOI: 10.3969/j.issn.1673-5749.2011.03.023 Abstract ( 1013 )   HTML ( 3 )   PDF（pc） (112KB) ( 619 )   Save Bone or bone substitute material graft is always introduced when the dental bone defect occurs due to trauma, infection, or tumor surgery. As the application of dental implants became more scientific, bone augmentation technique is now widely used and plenty of researches have been done on bone substitutes. Deminerlized dentin matrix（DDM） is a widespread osteoinductive material these years, because it is easy to obtain. This article is a general review and conclusion of the classification preparation, effect, biocompatibility and the mechanism of osteoinduction of DDM. Related Articles | Metrics

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The clinical advance of Endocrown MA Xiao-min, LI Yan. Inter J Stomatol. 2011, 38 (3):  332-334.  DOI: 10.3969/j.issn.1673-5749.2011.03.024 Abstract ( 2829 )   HTML ( 21 )   PDF（pc） (131KB) ( 1461 )   Save Endocrown is a new restorative option which uses pulpal chamber for retention. It consists of a circular butt-joint margin and a central retention cavity inside the pulp chamber. The retention principle of Endocrown includes the retention form of pulp chamber and adhesive retention. The foundation of this technique is to use the surface available in the pulpal chamber to assume the stability and retention of the restoration through adhesive procedures. Guidelines for the preparation are dictated by the amount of remaining coronal substance. It is indicated to restore endodontically treated teeth with large area defect, especially for the short clinical crowns which could not be restored by post-and-core crowns. This technique represents a promising and conservative alternative to full crowns for the treatment of posterior nonvital teeth that require long-term protection and stability. In this paper, the advance of basic research and clinical application of Endocrown were reviewed. Related Articles | Metrics

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Research progress on the use of simvastatin in bone metabolism WANG Rui, WU Zhe. Inter J Stomatol. 2011, 38 (3):  335-338.  DOI: 10.3969/j.issn.1673-5749.2011.03.025 Abstract ( 1066 )   HTML ( 3 )   PDF（pc） (143KB) ( 1158 )   Save Simvastatin is a specific hydroxymethyl glutaryl coenzyme A reductase inhibitor, which inhibits endogenous cholesterol synthesis. Recent studies have found that simvastatin could promote osteoblasts proliferation and increase bone formation, so the scholars are increasingly concerned about the drug in the application of bone remodeling. There have been a large number of studies demonstrating the bone-promoting effect of local application with different carriers in various animal models. The effect of simvastatin for bone formation in vivo depends on the concentration of local administration, and people have been trying to find a suitable route of administration. The effects of the drug on the bone metabolism and its mechanism, dosage, carrier are summarize Related Articles | Metrics

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Research progress on corrosion behavior of dental alloys ZHAO Yao, LIU Jia-jun, MENG Yu-kun. Inter J Stomatol. 2011, 38 (3):  339-342.  DOI: 10.3969/j.issn.1673-5749.2011.03.026 Abstract ( 1142 )   HTML ( 5 )   PDF（pc） (139KB) ( 774 )   Save Development and application of dental alloys is currently a focus in dentistry. Increasing knowledge about interaction of dental alloys with oral tissues has resulted in evolution of high performance dental materials to meet the various requirements of the ever-changing oral environment. The dental alloys are generally placed in the mouths of patients where they need to resist mechanical load and corrosive environment. Corrosion can lead to poor esthetics, compromise of physical properties, or deteriorated biocompatibility. Therefore, it is important to know the corrosion resistance. The main interest of the present article is to review the corrosion behavior of those dental alloys including alloys for prosthetic purposes, dental amalgam, and alloys for orthodontic applications, as reported by various research workers. Related Articles | Metrics

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Research progress on treatment of open bite with implant anchorage LI Ren-mei, CHEN Zhen-qi. Inter J Stomatol. 2011, 38 (3):  343-345.  DOI: 10.3969/j.issn.1673-5749.2011.03.027 Abstract ( 906 )   HTML ( 5 )   PDF（pc） (135KB) ( 605 )   Save Open bite is a malocclusion deformity caused by several factors. It is one of the most challenging malocclusion in clinics for orthodontists. Implants have been increasingly used in orthodontic practice because of its small size, patient comfort, low cost, and so on. Implants can provide absolutely anchorage for molar upright and intrusion, correcting open bite and improving the profile of patients with the vertical dentoalveolar excess in molar area or excessive eruption of molars. This method is simple, without impaction of adjacent teeth and patient compliance. The aim of this review is to present and discuss the indications and diagnostic methods, clinical applications, adverse effects and stability of correcting open bite with implants. Related Articles | Metrics

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Research progress on dental sedation ZHOU Meng, XIE Hui-xu, LIU Lei. Inter J Stomatol. 2011, 38 (3):  346-348.  DOI: 10.3969/j.issn.1673-5749.2011.03.028 Abstract ( 954 )   HTML ( 4 )   PDF（pc） (108KB) ( 738 )   Save The development of sedation techniques has always been inextricably linked with the development of dentistry. Today, the most commonly used dental nitrous oxide sedation technique has been proved to be potential harmful to medical staff, thus new technology of dental sedation is needed. The literature of sedation in dentistry in the recent years focused on three main areas: Midazolam sedation, sedation with dexmedetomidine in dentistry and patient controlled sedation with propofol in dentistry. The aim of this review is to summarize the recent literature in this field and state the current sedation technique in dentistry. Related Articles | Metrics

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Application of zoledronic acid locally applied affects bone metabolism in stomatology MA Ting, ZHANG Jian. Inter J Stomatol. 2011, 38 (3):  349-353.  DOI: 10.3969/j.issn.1673-5749.2011.03.029 Abstract ( 1177 )   HTML ( 5 )   PDF（pc） (175KB) ( 715 )   Save Zoledronic acids as third generation of nitrogen-containing bisphosphoates are potent inhibitors of bone resorption. Jaws are plasitic due to the high level of bone metabolism, so issues related to bone metabolism in stomatology are of important significance. The review presents in recent years’advances on topical application of zoledronic acids which affects bone metabolism in the aspects of implant, fracture healing, chronic periodontitis treatment, healing of tooth extraction and might bring about osteonecrosis of the jaw. Related Articles | Metrics

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Current status of three -dimensional image fusion technique for craniofacial region ZHANG Yu -fang, ZHOU Nuo. Inter J Stomatol. 2011, 38 (3):  354-357.  DOI: 10.3969/j.issn.1673-5749.2011.03.030 Abstract ( 953 )   HTML ( 5 )   PDF（pc） (133KB) ( 1066 )   Save Three-dimensional image fusion technique for craniofacial region possesses incomparable and unique merits in craniofacial anthropometry, craniofacial structure evaluation, deformity diagnosis, treatment planning, surgical procedure simulation and outcome prediction in the fields of modern orthognathics, craniomaxillofacial plastic and reconstruction surgery, and orthodontics over other imaging techniques, showing its promising application value and prospect in the clinical practice and scientific research of above-mentioned subjects. This article reviewed the mode selection, basic principles, characteristics and applications of three-dimensional image fusion technique for craniofacial region. Related Articles | Metrics

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The detection of ureases of oral bacteria LUAN Xiao-ling, WANG Yan, FENG Xi-ping. Inter J Stomatol. 2011, 38 (3):  358-360.  DOI: 10.3969/j.issn.1673-5749.2011.03.031 Abstract ( 1861 )   HTML ( 3 )   PDF（pc） (110KB) ( 984 )   Save Urea can be continuously secreted out of the healthy individuals’saliva and gingival crevicular fluid, and it can be rapidly hydrolysed by ureases of oral bacteria. Ammonia generated by ureolysis can increase the pH value of oral environment, and this causes changes in dental plaque biofilms, thus reduces the initiation and progression of dental caries. As the significant impaction of ureolysis on the microbial pathogenesis in the oral cavity, the detection of urease activity might have a great help with the prevention and treatment of dental caries. This review will describe the detection methods of oral bacterial ureases reported in recent years from three different levels: Qualitative test, semi-quantitative test, and quantitative test respectively. Related Articles | Metrics

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Forkhead box C-2 gene and development of axial skelet CHEN Qi, ZHENG Qian. Inter J Stomatol. 2011, 38 (3):  361-363.  DOI: 10.3969/j.issn.1673-5749.2011.03.032 Abstract ( 909 )   HTML ( 3 )   PDF（pc） (117KB) ( 576 )   Save Forkhead box C-2（FoxC-2）, a transcriptional factor of forkhead family, as the transmitter of several gene signaling pathway. FoxC-2 is likely to play an important role during the development of axial skeleton, cardiovascular and lymphatic system. Summarize the framework and physiologic function of foxC-2 gene and it’s protein outcome contributed greatly to study the mechanism of the development of axial skeleton. Related Articles | Metrics

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Research progress on the osteogenesis effect of nel-like typeⅠgene and its application in bone tissue engineering LIU Qi, LI Zu-bing． Inter J Stomatol. 2011, 38 (3):  364-366.  DOI: 10.3969/j.issn.1673-5749.2011.03.033 Abstract ( 1047 )   HTML ( 4 )   PDF（pc） (113KB) ( 551 )   Save Nel-like typeⅠgene is a novel gene which was found overexpressed in pre-fused areas of craniosynostosis patients. It was applied in bone tissue engineering as a new growth factor because of its biological functions on inducing osteoblast differentiaton and enhancing osteogenesis effect. This article will summary a review about the osteogenesis effect of nel-like typeⅠgene and its application in bone tissue engineering according what we have known. Related Articles | Metrics

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Urokinase-type plasminogen activator and p38 mitogen-activated protein kinase signaling pathway in the invasion of head and neck tumor ZHONG Yi, WANG Li, CHEN Xin-ming. Inter J Stomatol. 2011, 38 (3):  367-369.  DOI: 10.3969/j.issn.1673-5749.2011.03.034 Abstract ( 965 )   HTML ( 4 )   PDF（pc） (112KB) ( 497 )   Save The degradation of extracellular matrix is an important prerequisite in tumor oncogenesis and invasion. Studies have shown that urokinase-type plasminogen activator（uPA） plays an important role in the degradation of extracellular matrix. It has been suggested that p38 mitogen-activated protein kinase（MAPK） signaling pathway can be involved in tumor invasion by regulating uPA expression. In this article, the research of p38MAPK-signaling pathway and uPA in the invasion of head and neck tumor are reviewed. Related Articles | Metrics

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Effects of lipopolysaccharide on biological activity of periodontal ligament cells KONG Ning -jing1, LIU Jian-guo1, LI Hou-xuan2, YAN Fu-hua2. Inter J Stomatol. 2011, 38 (3):  370-372.  DOI: 10.3969/j.issn.1673-5749.2011.03.035 Abstract ( 946 )   HTML ( 3 )   PDF（pc） (122KB) ( 1081 )   Save Lipopolysaccharide（LPS）, which is one of the main etiological factors of periodontitis has many kinds of biological and immunological activity. This article summarizes the effects of lipopolysaccharide on biological activity of periodontal ligament cells in research progress. Related Articles | Metrics