Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (3): 297-300.doi: 10.3969/j.issn.1673-5749.2011.03.014

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Two-component signal transduction system and the virulence-related characteristics of Streptococcus mutans

CHEN Jiao, ZHOU Zhi, JIANG Dan.   

  1. Dept. of Conservative Dentistry and Endodontics, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing 400015, China
  • Received:2009-11-23 Revised:2010-11-16 Online:2011-05-20 Published:2011-05-20

Abstract:

Two-component signal transduction system(TCSTS) plays an important role in the expression of virulence factors of Streptococcus mutans, such as the competence development, the formation of biofilm, the stability of structure, the production of bacteriocin, and the properties of acid production and resistance. It provides many ecological advantages to compete and survive in the dental plaque. This article is a review about the composition of TCSTS of Streptococcus mutans, the effect of TCSTS on the virulence-related characteristics of Streptococcus mutans, and the application significance of TCSTS.

Key words: Streptococcus mutans, quorum sensing signaling system, two-component signal transduction system


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