Inter J Stomatol ›› 2017, Vol. 44 ›› Issue (1): 118-124.doi: 10.7518/gjkq.2017.01.024

• ·Reviews· • Previous Articles    

Biological activity of Enterococcus faecalis and Streptococcus mutans lipoteichoic acid

Liu Kun, Hou Benxiang.   

  1. Dept. of Conservative Dentistry and Endodontics, The Affiliated Beijing Stomatological Hospital of Capital Medical University, Beijing 100050, China
  • Received:2016-04-23 Online:2017-01-01 Published:2017-01-01

Abstract: Enterococcus faecalis(E. faecalis) is commonly detected in refractory and chronic periapical periodontal infections and is one of the main pathogenic bacteria in the root canal. Streptococcus mutans(S. mutans) is the main pathogenic bacteria caused by dental caries. E. faecalis and S. mutans virulence factors of lipoteichoic acid(LTA) can promote cells to secrete inflammatory factor, which leads to inflammation, promotes the absorption of periapical alveolar bone, and contributes to bacterial adhesion on tooth surface and biofilm formation. E. faecalis and S. mutans LTA in pathogenic bacteria is important, but its ultimate function is unclear. Therefore, this study investigates the pathogenic mechanism and molecular structure of LTA to understand the blockage of pathogenic pathway and thus reduce its pathogenicity.

Key words: Enterococcus faecalis, Streptococcus mutans, lipoteichoic acid, biological activity, pathogenic mechanism

CLC Number: 

  • R780.2

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