Int J Stomatol ›› 2023, Vol. 50 ›› Issue (1): 19-24.doi: 10.7518/gjkq.2023020

• Periodontitis • Previous Articles     Next Articles

Research progress on the role and mechanism of occlusal trauma in the development of periodontitis

Liu Tiqian(),Liang Xing(),Liu Weiqing,Li Xiaohong,Zhu Rui.   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2022-06-26 Revised:2022-10-10 Online:2023-01-01 Published:2023-01-09
  • Contact: Xing Liang;


Periodontitis is the most common reason for adult tooth loss, which negatively impacts the physical and mental health of patients. Recent studies have shown that occlusal trauma might be a risk factor for periodontitis: although occlusal force did not initiate periodontal disease, it could aggravate periodontitis. Therefore, this paper reviews the role of occlusal trauma in promoting inflammation, inhibiting osteogenesis, stimulating osteoclastogenesis, and related mole-cular mechanisms during the onset and progression of periodontitis.

Key words: periodontitis, occlusal trauma, inflammation, osteogenic differentiation, osteoclastogesis

CLC Number: 

  • R 781.4+5

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