Int J Stomatol

Int J Stomatol ›› 2019, Vol. 46 ›› Issue (6): 670-674.doi: 10.7518/gjkq.2019076

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Research progress on Porphyromonas gingivalis outer membrane vesicles

Zhang Zhiying1,Liu Dongjuan2,Pan Yaping1()   

  1. 1. Dept. of Peridontology, Hospital of Stomatology, China Medical University, Shenyang 110002, China
    2. Dept. of Emergency and Oral Medicine, Hospital of Stomatology, China Medical University, Shenyang 110002, China
  • Received:2019-01-21 Revised:2019-05-21 Online:2019-11-01 Published:2019-11-14
  • Contact: Yaping Pan E-mail:yppan@cmu.edu.cn
  • Supported by:
    This study was supported by National Natural Science Foundation of China(81670997);Postdoctoral Funds in China(2018M640269)

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Abstract:

Porphyromonas gingivalis is one of the major periodontal pathogens. Studies have shown that outer membrane vesicle (OMV) can exchange information with host cells and other microorganisms and transmit virulence factors to cause changes in host cells. Virulence factors contained in OMV mainly include adhesins and proteolytic enzymes, which play important roles in the pathogenesis of Porphyromonas gingivalis infection. This paper reviews the occurrence of Porphyromonas gingivalis OMV and its role in the pathogenesis of Porphyromonas gingivalis infection, thereby providing a reference for the in-depth study ofPorphyromonas gingivalis OMV.

Key words: periodontitis, Porphyromonas gingivalis, outer membrane vesicle

CLC Number: 

  • Q256

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