Int J Stomatol

Int J Stomatol ›› 2024, Vol. 51 ›› Issue (4): 425-432.doi: 10.7518/gjkq.2024059

• Periodontitis • Previous Articles     Next Articles

Progress of research on the correlation between periodontitis and heart failure

Shili Liu(),Lei Zhao()   

  1. State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Periodontology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2023-10-05 Revised:2024-03-20 Online:2024-07-01 Published:2024-06-24
  • Contact: Lei Zhao E-mail:1640286724@qq.com;jollyzldoc@163.com
  • Supported by:
    National Natural Science Foundation of China(81970944);Sichuan Provincial Natural Science Foundation of China(2023NSFSC0553);Chengdu Science and Technology Project(2021-YF05-01864-SN)

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Abstract:

Heart failure (HF) is a serious manifestation or terminal stage of various heart diseases, seriously affecting the physical and mental health of patients. Its etiology is explored through many aspects, among which the influence of inflammation on the HF process is a scholarly research hotspot. Periodontitis is a destructive disease of periodontal soft and hard tissues caused by plaque biofilm and is one of the two major oral diseases. Periodontitis is reportedly associated significantly with cardiovascular disease (CVD). The relationship between periodontitis and HF and its mechanism remain in the initial stage of research. Periodontal pathogens and their toxic products can reportedly affect myocardial function directly and indirectly, thereby affecting HF progression. This work provides a review of the progress of research on perio-dontitis and HF to provide some research ideas for the joint prevention and treatment of periodontitis and CVD.

Key words: heart failure, periodontitis, cardiac remodeling, cardiomyocyte

CLC Number: 

  • R783

TrendMD: 

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