Int J Stomatol ›› 2024, Vol. 51 ›› Issue (2): 227-232.doi: 10.7518/gjkq.2024022

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Process and progress in the clinical research of minimally invasive non-operative periodontal therapy technology

Yuhong Ma(),Lei Zhao()   

  1. State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Periodontology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2023-04-30 Revised:2023-11-07 Online:2024-03-01 Published:2024-03-11
  • Contact: Lei Zhao E-mail:467816053@qq.com;jollyzldoc@163.com
  • Supported by:
    National Natural Science Foundation of China(81970944);Chengdu Science and Technology Bureau Key Research and Development Support Project(2021-YF05-01864-SN)

Abstract:

Periodontitis is one of the main causes of tooth loss. Traditional non-surgical periodontal therapy (NSPT) is the first step of standardizing periodontal sequence therapy. However, the therapeutic effect of NSPT is limited in patients with moderate to severe periodontitis with intrabony defects. The minimally invasive non-surgical periodontal therapy (MINST) was proposed with the development of minimally invasive dental treatment. MINST is the technology of nonsurgical periodontal treatment with minimally invasive operation. This technology can replace periodontal surgery within certain conditions, improve the periodontal clinical parameters of intrabony defects, reduce postoperative pain, and improve the aesthetic and patient satisfaction of the MINST therapy outcome. This study summarizes the progress of the proposal and clinical application of MINST technology, analyzes the effect of the technology on traditional periodontal nonsurgical treatment and minimally invasive periodontal surgical treatment, and summarizes the application progress of this technology combined with other adjuvant treatments (including local medication, enamel matrix proteins, and periodontal endoscopy).

Key words: periodontitis, intrabony defect, non-surgical periodontal treatment, minimally invasive treatment

CLC Number: 

  • R783

TrendMD: 
1 Ghuman MS. Non-surgical periodontal therapy-evidence and opinion[J]. Prim Dent J, 2020, 8(4): 28-33.
2 Agrawal N, Agrawal K, Mhaske S. An uncommon presentation of an inflammatory gingival enlargement: responding to non-surgical periodontal therapy[J]. Int J Dent Hyg, 2011, 9(4): 303-307.
3 Nibali L. Intrabony defects and non-surgical treatment[J]. Prim Dent J, 2014, 3(3): 48-50.
4 Heitz-Mayfield LJ, Lang NP. Surgical and nonsurgical periodontal therapy. Learned and unlearned concepts[J]. Periodontol 2000, 2013, 62(1): 218-231.
5 Kotík L. The geriatric patient and surgery[J]. Vnitr Lek, 2018, 64(11): 1067-1069.
6 Cobb CM, Sottosanti JS. A re-evaluation of scaling and root planing[J]. J Periodontol, 2021, 92(10): 1370-1378.
7 Mombelli A, Nyman S, Brägger U, et al. Clinical and microbiological changes associated with an altered subgingival environment induced by periodontal pocket reduction[J]. J Clin Periodontol, 1995, 22(10): 780-787.
8 Bower RC. Furcation morphology relative to perio-dontal treatment. Furcation entrance architecture[J]. J Periodontol, 1979, 50(1): 23-27.
9 Hou GL, Chen SF, Wu YM, et al. The topography of the furcation entrance in Chinese molars. Furcation entrance dimensions[J]. J Clin Periodontol, 1994, 21(7): 451-456.
10 Graziani F, Gennai S, Cei S, et al. Clinical performance of access flap surgery in the treatment of the intrabony defect. A systematic review and meta-analysis of randomized clinical trials[J]. J Clin Perio-dontol, 2012, 39(2): 145-156.
11 Mei CC, Lee FY, Yeh HC. Assessment of pain perception following periodontal and implant surgeries[J]. J Clin Periodontol, 2016, 43(12): 1151-1159.
12 Ribeiro FV, Casarin RC, Palma MA, et al. Clinical and patient-centered outcomes after minimally invasive non-surgical or surgical approaches for the treatment of intrabony defects: a randomized clinical trial[J]. J Periodontol, 2011, 82(9): 1256-1266.
13 Nibali L, Pometti D, Chen TT, et al. Minimally invasive non-surgical approach for the treatment of perio-dontal intrabony defects: a retrospective analysis[J]. J Clin Periodontol, 2015, 42(9): 853-859.
14 Nibali L, Yeh YC, Pometti D, et al. Long-term stability of intrabony defects treated with minimally invasive non-surgical therapy[J]. J Clin Periodontol, 2018, 45(12): 1458-1464.
15 Acunzo R, Gorbunkova A, Rezzolla M, et al. Short-term effect of regular vs mini curettes on periodontal tissue according to phenotype: a randomized control clinical trial[J]. Int J Esthet Dent, 2021, 16(3): 364-374.
16 Abdul Hayei NA, Yahya NA, Safii SH, et al. Influence of scaler tip design on root surface roughness, tooth substance loss and patients' pain perception: an in vitro and a randomised clinical trial[J]. BMC Oral Health, 2021, 21(1): 169.
17 Chung WC, Huang CF, Feng SW. Clinical benefits of minimally invasive non-surgical periodontal thera-py as an alternative of conventional non-surgical periodontal therapy-a pilot study[J]. Int J Environ Res Public Health, 2022, 19(12): 7456.
18 Nibali L, Koidou V, Salomone S, et al. Minimally invasive non-surgical vs. surgical approach for perio-dontal intrabony defects: a randomised controlled trial[J]. Trials, 2019, 20(1): 461.
19 Cortellini P, Tonetti MS. Improved wound stability with a modified minimally invasive surgical technique in the regenerative treatment of isolated interdental intrabony defects[J]. J Clin Periodontol, 2009, 36(2): 157-163.
20 Cortellini P, Tonetti MS. Clinical and radiographic outcomes of the modified minimally invasive surgical technique with and without regenerative mate-rials: a randomized-controlled trial in intra-bony defects[J]. J Clin Periodontol, 2011, 38(4): 365-373.
21 Iorio-Siciliano V, Ramaglia L, Isola G, et al. Chan-ges in clinical parameters following adjunctive local sodium hypochlorite gel in minimally invasive nonsurgical therapy (MINST) of periodontal pockets: a 6-month randomized controlled clinical trial[J]. Clin Oral Investig, 2021, 25(9): 5331-5340.
22 Aimetti M, Ferrarotti F, Mariani GM, et al. A novel flapless approach versus minimally invasive surgery in periodontal regeneration with enamel matrix derivative proteins: a 24-month randomized controlled clinical trial[J]. Clin Oral Investig, 2017, 21(1): 327-337.
23 Anoixiadou S, Parashis A, Vouros I. Enamel matrix derivative as an adjunct to minimally invasive non-surgical treatment of intrabony defects: a rando-mized clinical trial[J]. J Clin Periodontol, 2022, 49(2): 134-143.
24 Eichenberger M, Biner N, Amato M, et al. Effect of magnification on the precision of tooth preparation in dentistry[J]. Oper Dent, 2018, 43(5): 501-507.
25 Corbella S, Taschieri S, Cavalli N, et al. Comparative evaluation of the use of magnification loupes in supragingival scaling procedures[J]. J Investig Clin Dent, 2018, 9(2): e12315.
26 徐玉娟, 赵蕾, 吴亚菲, 等. 牙周内窥镜辅助龈下刮治治疗残存牙周袋的临床研究[J].华西口腔医学杂志, 2021, 39(4): 441-446.
Xu YJ, Zhao L, Wu YF, et al. Clinical study of perio-dontal endoscope-assisted subgingival scaling in the treatment of residual pocket[J]. West China J Stomatol, 2021, 39(4): 441-446.
27 Wu J, Lin LY, Xiao JP, et al. Efficacy of scaling and root planning with periodontal endoscopy for residual pockets in the treatment of chronic periodontitis: a randomized controlled clinical trial[J]. Clin Oral Investig, 2022, 26(1): 513-521.
28 Movila A, Kajiya M, Wisitrasameewong W, et al. Intravital endoscopic technology for real-time monitoring of inflammation caused in experimental perio-dontitis[J]. J Immunol Methods, 2018, 457: 26-29.
29 Kuang YC, Hu B, Chen J, et al. Effects of periodontal endoscopy on the treatment of periodontitis: a systematic review and meta-analysis[J]. J Am Dent Assoc, 2017, 148(10): 750-759.
30 Graetz C, Sentker J, Cyris M, et al. Effects of perio-dontal endoscopy-assisted nonsurgical treatment of periodontitis: four-month results of a randomized controlled split-mouth pilot study[J]. Int J Dent, 2022, 2022: 9511492.
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