Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (4): 444-448.doi: 10.7518/gjkq.2018.04.013

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Research progress on macrophage in bone tissue repair

Zhu Chenyou, Wei Shimin, Wang Yuanjing, Wu Yingying.   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2017-11-20 Revised:2018-04-10 Online:2018-07-02 Published:2018-07-02
  • Supported by:
    This study was supported by Program for Sichuan University Excellent Young Scholars Research Fund (2017SCU04A21), Sichuan Provincial Department of Science and Technology Talent Project (2018RZ0088), and Sichuan University Innovation and Entrepreneurship Training Program under Grants (C2018103082).

Abstract: The immune system is an important barrier for defense in the human body. This system includes B cells, T cells, dendritic cells (DC), and macrophages, which play a pivotal role in tissue injury, tumor, and bone remodeling. The understanding of macrophages has improved in the past years, but numerous mechanisms between macrophages and biomaterials remain largely unknown. Thus, the present study discusses the response between macrophages and biomaterials and predicts their potential application to provide new ideas for basic and clinical research.

Key words: macrophage, bone repair, dental implant, guided bone regeneration

CLC Number: 

  • Q813

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