Int J Stomatol

Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (6): 703-709.doi: 10.7518/gjkq.2018.06.014

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Research progress on the relationship between periodontitis and sclerostin

Caiwei Xu,Yi Xue(),Zhongyin Wu   

  1. Dept. of Stomatology, Bethune International Peace Hospital, Shijiazhuang 050000, China
  • Received:2017-11-04 Revised:2018-06-16 Online:2018-11-01 Published:2018-11-15
  • Contact: Yi Xue E-mail:dentvip@qq.com
  • Supported by:
    This study was supported by The 2017 Heibei Provincial Government Foundation for Medical Talent Training and Fundamental Research(2017-46)

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Abstract:

Alveolar bone resorption is one of the main pathological changes brought about by periodontitis. Sclerostin is characterized by suppressing bone formation. Sclerostin antibody could promote bone formation. Sclerostin is involved in the occurrence and progression of periodontitis. This paper reviews the progress of research on the relationship between sclerostin and periodontitis.

Key words: periodontitis, sclerostin, Wnt signaling pathway

CLC Number: 

  • R781.4 +2

TrendMD: 
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