Int J Stomatol

Inter J Stomatol ›› 2014, Vol. 41 ›› Issue (5): 613-616.doi: 10.7518/gjkq.2014.05.026

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Lipoxins and their role in the resolution of periodontitis

Zhou Qiao, Yang Jingmei, Xu Yi   

  1. State Key Laboratory of Oral Diseases, Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2013-09-25 Revised:2013-12-30 Online:2014-09-01 Published:2014-09-01

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Abstract:

Lipoxins(LX) are important endogenous lipid-derived anti-inflammatory transmitters that regulate the resolution of inflammation; they are considered the “braking signals” of inflammation. The local application of LX analogues has been shown to inhibit bone destruction distinctly and limit connective tissue infiltration by inflammatory and immune cells. Therefore, LX has an important function in the resolution of periodontal inflammation.

Key words: lipoxins, periodontitis, polymorphonuclear leukocyte

CLC Number: 

  • R 781.4

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