国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (3): 261-266.doi: 10.7518/gjkq.2018.03.003
张鑫, 汪成林, 杨静, 叶玲
Zhang Xin, Wang Chenglin, Yang Jing, Ye Ling
摘要： 牙髓干细胞是牙髓组织中具有自我更新能力及多向分化潜能的一类成体干细胞,在牙髓修复、牙齿再生以及骨组织工程中发挥重要作用。表观遗传是指在DNA序列不改变的前提下基因表达发生了可遗传的变化,主要包括DNA甲基化、组蛋白修饰、非编码RNA调控等。研究发现,通过调控基因的转录过程,表观调控在牙髓干细胞的各项生物学行为中起着重要作用。本文对牙髓干细胞的表观遗传调控进行综述。
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