Int J Stomatol

Inter J Stomatol ›› 2017, Vol. 44 ›› Issue (3): 340-343.doi: 10.7518/gjkq.2017.03.018

• Reviews • Previous Articles     Next Articles

Influence of cysteine cathepsins on dentin bonding durability

Liao Wenting, Li Yan.   

  1. Guanghua School of Stoma-tology, Dept. of Prosthodontics, Hospital of Stomatology, Sun Yat-sen University;
    Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2016-12-01 Revised:2017-02-12 Online:2017-05-01 Published:2017-05-01
  • Supported by:
    This study was supported by Science and Technology Planning Project of Guangdong Province(2013B051000030).

RichHTML

9

PDF (PC)

370

Abstract: Cysteine cathepsins are the major members of cathepsins. Exposed collagen is produced by demineralization during the process of dentin bonding. The degradation of the exposed collagen by endogenous proteases is one of the main factors that affect dentin bond durability. In addition to matrix metalloproteinases(MMPs), which play an important role in the decrease of dentin bonding durability, cysteine cathepsins are activated during the bonding process and then participate in the destruction of collagen in the hybrid layer. This study clarifies the interaction between cysteine cathepsins and MMPs and the influence ofcysteine cathepsinson dentin bonding and reviews the research progress of the application of cysteine cathepsins inhibitor in improving dentin bonding durability.

Key words: cysteine cathepsin, dentin bonding durability, matrix metalloproteinase, cysteine cathepsin inhibitor

CLC Number: 

  • R781.05

TrendMD: 
[1] Pashley DH, Tay FR, Yiu C, et al. Collagen degrada-tion by host-derived enzymes during aging[J]. J Dent Res, 2004, 83(3):216-221.
[2] Mazzoni A, Pashley D, Nishitani Y, et al. Reactiva-tion of inactivated endogenous proteolytic activities in phosphoric acid-etched dentine by etch-and-rinse adhesives[J]. Biomaterials, 2006, 27(25):4470-4476.
[3] Nishitani Y, Yoshiyama M, Wadgaonkar B, et al. Activation of gelatinolytic/collagenolytic activity in dentin by self-etching adhesives[J]. Eur J Oral Sci, 2006, 114(2):160-166.
[4] Dickinson DP. Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease[J]. Crit Rev Oral Biol Med, 2002, 13(3):238-275.
[5] Obermajer N, Jevnikar Z, Doljak B, et al. Role of cysteine cathepsins in matrix degradation and cell signalling[J]. Connect Tissue Res, 2008, 49(3):193- 196.
[6] Rossi A, Deveraux Q, Turk B, et al. Comprehensive search for cysteine cathepsins in the human genome [J]. Biol Chem, 2004, 385(5):363-372.
[7] Vasiljeva O, Dolinar M, Pungercar JR, et al. Recom-binant human procathepsin S is capable of autoca-talytic processing at neutral pH in the presence of glycosaminoglycans[J]. FEBS Lett, 2005, 579(5): 1285-1290.
[8] Caglic D, Pungercar JR, Pejler G, et al. Glycosa-minoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions[J]. J Biol Chem, 2007, 282(45):33076- 33085.
[9] Dubin G. Proteinaceous cysteine protease inhibitors [J]. Cell Mol Life Sci, 2005, 62(6):653-669.
[10] Tjäderhane L, Nascimento FD, Breschi L, et al. Op-timizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cys-teine cathepsins[J]. Dent Mater, 2013, 29(1):116- 135.
[11] Chen MK, Su SC, Lin CW, et al. Cathepsin B SNPs elevate the pathological development of oral cancer and raise the susceptibility to carcinogen-mediated oral cancer[J]. Hum Genet, 2012, 131(12):1861- 1868.
[12] Mogi M, Otogoto J. Expression of cathepsin-K in gingival crevicular fluid of patients with periodon-titis[J]. Arch Oral Biol, 2007, 52(9):894-898.
[13] Garg G, Pradeep AR, Thorat MK. Effect of nonsur-gical periodontal therapy on crevicular fluid levels of cathepsin K in periodontitis[J]. Arch Oral Biol, 2009, 54(11):1046-1051.
[14] Alan R, Marakoğlu İ, Haliloğlu S. Peri-implant crevicular fluid levels of cathepsin-K, RANKL, and OPG around standard, short, and mini dental im-plants after prosthodontic loading[J]. J Periodontal Implant Sci, 2015, 45(5):169-177.
[15] Nascimento FD, Minciotti CL, Geraldeli S, et al. Cysteine cathepsins in human carious dentin[J]. J Dent Res, 2011, 90(4): 506-511.
[16] Palosaari H, Pennington CJ, Larmas M, et al. Expre-ssion profile of matrix metalloproteinases(MMPs) and tissue inhibitors of MMPs in mature human odontoblasts and pulp tissue[J]. Eur J Oral Sci, 2003, 111(2):117-127.
[17] De Munck J, Van den Steen PE, Mine A, et al. Inhi-bition of enzymatic degradation of adhesive-dentin interfaces[J]. J Dent Res, 2009, 88(12):1101-1106.
[18] Cox SW, Eley BM, Kiili M, et al. Collagen degrada-tion by interleukin-1beta-stimulated gingival fibro-blasts is accompanied by release and activation of multiple matrix metalloproteinases and cysteine proteinases[J]. Oral Dis, 2006, 12(1):34-40.
[19] Hadler-Olsen E, Fadnes B, Sylte I, et al. Regulation of matrix metalloproteinase activity in health and disease[J]. FEBS J, 2011, 278(1):28-45.
[20] Boukpessi T, Menashi S, Camoin L, et al. The effect of stromelysin-1(MMP-3) on non-collagenous ex-tracellular matrix proteins of demineralized dentin and the adhesive properties of restorative resins[J]. Biomaterials, 2008, 29(33):4367-4373.
[21] Garnero P, Ferreras M, Karsdal MA, et al. The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation[J]. J Bone Miner Res, 2003, 18(5):859-867.
[22] Lehmann N, Debret R, Roméas A, et al. Self-etching increases matrix metalloproteinase expression in the dentin-pulp complex[J]. J Dent Res, 2009, 88(1):77- 82.
[23] Zhang W, Yang W, Wu S, et al. Effects of acid etch-ing and adhesive treatments on host-derived cysteine cathepsin activity in dentin[J]. J Adhes Dent, 2014, 16(5):415-420.
[24] Dung SZ, Gregory RL, Li Y, et al. Effect of lactic acid and proteolytic enzymes on the release of organic matrix components from human root dentin[J]. Caries Res, 1995, 29(6):483-489.
[25] Tersariol IL, Geraldeli S, Minciotti CL, et al. Cys-teine cathepsins in human dentin-pulp complex[J]. J Endod, 2010, 36(3):475-481.
[26] Vidal CM, Tjäderhane L, Scaffa PM, et al. Abun-dance of MMPs and cysteine cathepsins in caries-affected dentin[J]. J Dent Res, 2014, 93(3):269-274.
[27] Ricci HA, Sanabe ME, de Souza Costa CA, et al. Chlorhexidine increases the longevity of in vivo resin-dentin bonds[J]. Eur J Oral Sci, 2010, 118(4): 411-416.
[28] Scaffa PM, Vidal CM, Barros N, et al. Chlorhexidine inhibits the activity of dental cysteine cathepsins[J]. J Dent Res, 2012, 91(4):420-425.
[29] Tezvergil-Mutluay A, Agee KA, Mazzoni A, et al. Can quaternary ammonium methacrylates inhibit matrix MMPs and cathepsins[J]. Dent Mater, 2015, 31(2): e25-e32.
[30] 杨伟湘, 张文浩, 吴淑仪, 等. 不同浓度组织蛋白酶抑制剂E-64对牙本质与树脂粘接耐久性的影响[J]. 中华口腔医学杂志, 2013, 48(6):368-371.
Yang WX, Zhang WH, Wu SY, et al. Effect of dif-ferent molarity cathepsins specific inhibitor E-64 on dentin-resin bonding durability[J]. Chin J Stomatol, 2013, 48(6):368-371.
[1] Li Guiping,Qin Xu,Zhu Guangxun.. Research progress on adenosine monophosphate-activated protein kinase in periodontal disease [J]. Int J Stomatol, 2022, 49(3): 343-348.
[2] Liu Enyan,Li Mingyun. Research progress on tea polyphenols in dentin adhesion [J]. Int J Stomatol, 2020, 47(6): 732-738.
[3] Li Lanjiang1, Xu Bingying1, Yang Chunyan2, Zhao Chuan3, Tian Xin2.. Matrix metalloproteinase 1, 3 and 9 gene polymorphism and the risk of oral squamous cell carcinomas among Han Chinese in Yunnan [J]. Inter J Stomatol, 2015, 42(6): 631-634.
[4] Li Ming, Peng Jieying, Wu Yingfang, Zhang Rui. Arecoline upregulated matrix metalloproteinase 9 expression in HaCaT cells [J]. Inter J Stomatol, 2015, 42(2): 166-169.
[5] Yuan Lin, Chen Xie, Cheng Feng, Yang Zhengyi, Pan Guangsi, Wang Han, Sun Jin, Cao Yina. Matrix metalloproteinase 2 expression in implant-bone interface remodeling influenced by submerged and nonsubmerged implant denture [J]. Inter J Stomatol, 2014, 41(6): 631-634.
[6] Li Guangyue, Xie Yun, Yue Yuan, Bai Congjia, Hao Liang, Wang Min. The effect of angiotensin Ⅱ on the expression of osteopontin and matrix metalloproteinase-2 in mice osteoblast [J]. Inter J Stomatol, 2013, 40(3): 291-296.
[7] Liu Panlong1,Zhou Hongyan2,Wang Dongmiao3,Mei Yufeng1.. Research progress on pathogenesis of dental fluorosis [J]. Inter J Stomatol, 2013, 40(1): 94-97.
[8] Wang Heng, Teng Wei.. Matrix metalloproteinases’influence on durability of dentin bonding [J]. Inter J Stomatol, 2012, 39(4): 498-500.
[9] Liu Jia, Ling Junqi.. Research progress on matrix metalloproteinase activity regulated by high glucose and the relationship with dental caries [J]. Inter J Stomatol, 2011, 38(5): 574-577.
[10] ZHANG Xin, GU Zhi-yuan.. Expression and effects of membrane type-1-matrix metalloprotease on bone metabolism, oral development and diseases [J]. Inter J Stomatol, 2011, 38(2): 225-228.
[11] HUANG Jia-cheng, LIN Xue-feng. Host-derived matrix metalloproteinase and resin adhesion [J]. Inter J Stomatol, 2010, 37(01): 62-64.
[12] WANG Jiao-cui, ZHAO Wei. Present study of physiologic root resorption in primary teeth [J]. Inter J Stomatol, 2009, 36(3): 300-302.
[13] XIE Yong-jian, MAI Li-xiang, ZHANG Sheng, GUO Hui, WANG Yang, WANG Da-wei. The expr ession of matr ix metalloproteinase- 1 and tissue inhibitor s of metallo [J]. Inter J Stomatol, 2008, 35(5): 481-481～484，605.
[14] REN Xiang, ZHU En - xin, XIAO Jing, LIU Ting- jiao, QU Hong, SU Ying- ying. Expr ession of matr ix metalloproteinase- 7 and c- myc in human or al squamous ce [J]. Inter J Stomatol, 2008, 35(3): 229-229～232，353.
[15] MAI Li- xiang, XIE Yong- jian, WANG Da- wei.. Research Progress of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Root Absorbion [J]. Inter J Stomatol, 2007, 34(03): 188-191.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .