国际口腔医学杂志 ›› 2019, Vol. 46 ›› Issue (1): 48-54.doi: 10.7518/gjkq.2019.01.009

• 综述 • 上一篇    下一篇

种子细胞在牙周组织再生治疗中的研究进展

董正谋1,刘锐2,刘鲁川2(),温秀杰2   

  1. 1. 红安县人民医院口腔科 红安 438400
    2. 陆军军医大学大坪医院野战外科研究所口腔医学中心 重庆 400042
  • 收稿日期:2018-01-22 修回日期:2018-06-11 出版日期:2019-01-01 发布日期:2019-01-11
  • 通讯作者: 刘鲁川 E-mail:LiuLuchuan1957@126.com
  • 作者简介:董正谋,副主任医师,硕士,Email:DZM666999@163.com
  • 基金资助:
    全军医学科研“十一五”计划面上项目(06MB252)

Research progress on the seed cells in periodontal tissue regeneration

Zhengmou Dong1,Rui Liu2,Luchuan Liu2(),Xiujie Wen2   

  1. 1. Dept. of Stomatology, The People’s Hospital of Hong’an County, Hong’an 438400, China;
    2. Dept. of Stomatology Medical Center, Institute of Field Surgery, Daping Hospital, Army Medical University, Chongqing 400042, China
  • Received:2018-01-22 Revised:2018-06-11 Online:2019-01-01 Published:2019-01-11
  • Contact: Luchuan Liu E-mail:LiuLuchuan1957@126.com
  • Supported by:
    This study was supported by the Army Medical Research Program of '11th Five-Year'(06MB252)

摘要:

牙周病是一种慢性感染性疾病,可破坏牙周组织,甚至导致牙齿丧失。随着对牙周病发病机制认识的不断深入,治疗重点已从药物、机械治疗阻止疾病发展转变为促进牙周组织的再生和重建。牙周组织工程已成为牙周病治疗的新方向。牙周组织再生治疗的三大要素为种子细胞、生长因子和支架材料,种子细胞是牙周组织再生治疗最关键的部分之一。本文就牙周组织再生治疗的种子细胞的研究进展进行综述。

关键词: 牙周病, 组织工程, 牙周组织再生治疗, 种子细胞

Abstract:

Periodontal disease is a chronic infectious disease that can lead to the destruction of periodontium and teeth loss. Following the deepening study on its pathogenesis, the key to treatment has gradually turned from preventing the disease on drugs and mechanical treatment development to promoting the periodontium regeneration and reconstruction. Periodontal tissue engineering technology is the new direction of periodontal tissue regeneration treatment. Periodontal tissue regeneration treatments contains seed cells, growth factors, and scaffold materials. The selection of seed cell group is one of the most important parts of periodontal tissue regeneration. This paper mainly introduces the research progress of seed cells in periodontal tissue regeneration.

Key words: periodontal disease, tissue engineering, periodontal tissue regeneration, seed cell

中图分类号: 

  • R781.4 +2
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