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Table of Content

    01 January 2013, Volume 40 Issue 1 Previous Issue    Next Issue
    Causes and treatment of the common retaining complication for the implant supported edentulous
    Song YingLiang.
    Inter J Stomatol. 2013, 40 (1):  3-5.  DOI: 10.7518/gjkq.2013.01.001
    Abstract ( 1774 )   HTML ( 3 )   PDF(pc) (5282KB) ( 1282 )   Save

    In recent years, a great power has been provided to the development of oral implantology because of the more and more implant supported denture demands from the edentulous people, which also brings many problems. The purpose of this article is to review the causes and treatment of the common retaining complication from 2001 when department of implantation in hospital of stomatology of the Fourth Military Medical University founded.

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    The expression of Ezrin protein in oral squamous cell carcinoma
    Sun Peng 1,Cheng Fangjing 2,Jiang Tao 3,Liang Shangzheng 4.
    Inter J Stomatol. 2013, 40 (1):  6-9.  DOI: 10.7518/gjkq.2013.01.002
    Abstract ( 1832 )   HTML ( 1 )   PDF(pc) (1579KB) ( 793 )   Save

    Objective To detect the expression of Ezrin in oral squamous cell carcinoma(OSCC), paratumor tissue and normal tissue and to probe the relationship between OSCC in the process of development and the role of lymph node metastasis. Methods Detecting the patients which did not receive radiotherapy and chemotherapy, including 50 cases with OSCC surgical resection specimens, 15 specimens of paratumor tissue, and 15 specimens of normal tissue. Serial sections of the blocks or microarrays were stained with immunohistochemical SP methods using mouse anti human monoclonal antibodies against Ezrin. Using semi -quantitative integration method to determine the outcomes, which were statistical analysed, and conclude finally. Results 1)The positive rates of Ezrin were 26.67%, 53.34%, 78.00% in normal tissue, paratumor tissue and OSCC, respectively(P<0.05). 2)The expresion of Ezrin were increased gradually in OSCC, paratumor and normal tissue, one adjacent OSCC and paratumor tissue, paratumor tissue and normal tissue, OSCC and normal tissue between the expression of difference was significant(P<0.05). 3)The expression of Ezrin correlated with lymph node metastasis(P<0.05), not with histological grade(P>0.05). Conclusion  1)Ezrin may play an important role in the development of OSCC. 2)Detection of OSCC tissue Ezrin expression levels may contribute to OSCC with lymph node metastasis is a potential forecast. 3)The expression of Ezrin in OSCC correlated with lymph node metastasis, not with histological type.

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    Effects of cinnamaldehyde on oral squamous carcinoma cell in vitro
    Cao Guifen1, Xie Ping2, Huang Ping3, Qi Ganggang1, Zhang Hua2, Liu Daozhou2.
    Inter J Stomatol. 2013, 40 (1):  10-13.  DOI: 10.7518/gjkq.2013.01.003
    Abstract ( 1791 )   HTML ( 1 )   PDF(pc) (458KB) ( 846 )   Save

    Objective To investigate the inhibiting in vitro effect of cinnamaldehyde on human oral squamous carcinoma cell. Methods Using methyl thiazolyl tetrazolium(MTT) to assay the effect of cinnamaldehyde on human tongue carcinoma cell lines(Tca8113), human buccal squamous carcinoma cell lines(BCaCD885), human oral epithelial carcinoma KB cell in different concentrations. The final concentrations of cinnamaldehyde were from 8 to 256 mg·L-1 , respectively. The cells were cultured in different concentrations, and the cinnamaldehyde continuously contacted with the cells for 24, 48 and 72 h, respectively, we compared the efficacy of cinnamaldehyde in different concentration groups during different time quantum. Differences between data obtained were statistically analyzed using analysis of variance(ANOVA) in SPSS 16.0. Results When the concentration of cinnamicaldehyde were from 32 to 256 mg·L-1 , it had a significant inhibition on the proliferation of oral cancer cells in vitro, and with a increasing concentration of cinnamicaldehyde, the efficacy of inhibition became more significant, which showed an obvious dosage-efficacy relationship. When cinnamaldehyde acted 24 hours or its concentration was 16 mg·L-1 , the inhibition rate was 58.33% for the human tongue squamous cell carcinoma cell line Tca8113; when the concentration was on the level of 32 mg·L-1 , the inhibition rate were 66.08%, 76.61% respectively for human oral epithelial carcinoma KB cell and human buccal squamous carcinoma cell BCaCD885, respectively. Conclusion In the medium-high(from 32 to 256 mg·L-1 ) concentrations of cinnamaldehyde showed remarkable cytostatic activity in terms of inhibition the proliferation of oral squamous carcinoma epithelial cell.

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    The effects of alveolar bone quality on stress of tooth/implant-supported restoration connected by precision attachment
    Zhang Xingle, Li Lei, Li Le, Wang Peng, Zhou Yanmin.
    Inter J Stomatol. 2013, 40 (1):  14-16.  DOI: 10.7518/gjkq.2013.01.004
    Abstract ( 1669 )   HTML ( 3 )   PDF(pc) (1101KB) ( 511 )   Save

    Objective  To investigate the effects of alveolar bone quality on stress of tooth/implant-supported restoration connected by precision attachment using three-dimensional finite element approach. Methods The FEM was applied to analyze the stress distribution of tooth/implant-supported restoration connected by precision attachment under various loading conditions when the alveolar bone quality is changed. Results The stress values of the tooth, implant and their surrounding bone increased when the quality of their surrounding bone decreased. Conclusion The stress values of the tooth, implant and their surrounding bone were closely related with the bone quality.

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    Comparison of diagnostic value of cone beam computed tomography and orthpantomography for root fracture
    Liu Jian1,Zhang Haowei2,Wu Jiahan1,Li Shaoyue2,Huang Lijia2,Yang Ping2.
    Inter J Stomatol. 2013, 40 (1):  17-19.  DOI: 10.7518/gjkq.2013.01.005
    Abstract ( 1917 )   HTML ( 1 )   PDF(pc) (675KB) ( 900 )   Save

    Objective To evaluate the diagnostic value of cone beam computed tomography(CBCT) and orthpantomography(OPG) for root fracture. Methods Comparing the results of 31 teeth from 30 suspected patients of root fracture examined by CBCT and OPG. Results Root fractures were confirmed in all the 31 teeth by CBCT and subsequent extraction while OPG only detected fractures in 23 teeth. Conclusion CBCT images can more distinctly demonstrate the fracture lines, and surrounding bone loss in three dimensions. And CBCT is superior to OPG in detection of root fractures.

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    Investigation and analysis of oral health behaviour and dietary habits among undergraduates
    Jing Huan, Wu Yeke, Li Hui, Liao Ying, Ruan Mengjiao, Zeng Wei, Zhang Jingyang, Huang Dingming.
    Inter J Stomatol. 2013, 40 (1):  20-23.  DOI: 10.7518/gjkq.2013.01.006
    Abstract ( 1775 )   HTML ( 5 )   PDF(pc) (569KB) ( 1054 )   Save

    Objective Our aim was to study the oral health behaviour and dietary habits of undergraduates on campus. In order to provide original data for improving oral health education and putting forward an optimized educational pattern. Methods Stratified sampling was used to pick up 1 500 undergraduates from Sichuan University. Participants were investigated by using questionaires on oral health behaviour and dietary habits. Results Most students brushed tooth for keeping tone fresh. The frequency and amount of sugary food intake was mostly once or twice a week and 100~400 g perspectively. Girls ate sugary food in significant higher frequency while boys drank more beverage both in frequency and amount. The majority of students did nothing after taking sugary food and they also failed to pay dental visits when the tooth appearances had changed or toothache had occurred. Unless the hurt feeling had overpassed their tolerance would they consult dentists. Conclusion Most undergraduates lack oral health behavior. Frequency and amount of taking sugary food were in high level while dental visit inclination was low. Universities as well as other institutes should emphasize oral health propaganda and education to improve undergraduates ’ oral health consciousness.

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    Clinical study on fiber-reinforced post and cast metal post applied in serious posterior teeth defect restoration
    Liu Chang, Xue Li, Zhang Yu.
    Inter J Stomatol. 2013, 40 (1):  24-27.  DOI: 10.7518/gjkq.2013.01.007
    Abstract ( 1649 )   HTML ( 6 )   PDF(pc) (472KB) ( 1244 )   Save

    Objective To evaluate the clinical effect of fiber-reinforced post and cast metal post applied to restore serious posterior teeth defect. Methods One hundred and six serious defect posterior teeth from 97 patients were randomly divided into two groups after root canal treatment. Fifty two teeth in one group were restored with fiber-reinforced post while 54 teeth in the other group restored with cast metal post. Porcelain fused to metal crowns were applied in both groups. After 12-24 months observation, the survival rate of each group were followed up and analyzed by SPSS software package for χ test. Results Two out of 52 teeth failed in the fiber-reinforced post group while 6 out of 54 teeth in the cast metal post group. There was statistical difference between two groups in survival rate. Conclusion Fiber-reinforced post can be used as ideal restoration material in serious defect posterior teeth.

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    Diseases misdiagnosed as temporomandibular disorders and the appropriateness of terminology for classification of such literatures Yang
    Yang Xianrui1,Li Chunjie2,Shi Zongdao3,Su Naichuan4.
    Inter J Stomatol. 2013, 40 (1):  28-32.  DOI: 10.7518/gjkq.2013.01.008
    Abstract ( 1686 )   HTML ( 1 )   PDF(pc) (565KB) ( 937 )   Save

    Objective To summarize all the related reports to explore causes of the misdiagnoses of other diseases as temporomandibular disorder(TMD) and develop strategies in reducing the misdiagnosis, and to assess appropriateness of using“systematic review” in replace of“review” for this kind of literatures. Methods Medline (via OVID), EMBASE, Chinese BioMedical Literature Database(CBM), China National Knowledge Infrastructure (CNKI) and VIP Database for Chinese Technical Periodicals(VIP) were searched electronically till December, 2011 for identifying the case reports, case series or “systematic reviews” of misdiagnoses of other diseases as TMD. The eligible studies were selected and extracted by two independent reviewers. All the data were summarized to show distributions of other diseases and classifications of the possible causes of the misdiagnoses. For second aim of the study, some so-called systematic reviews on misdiagnosis in which only case reports or case series being included were also collected, to explore appropriateness of the term “systematic review” for such literatures. Results A total of 21 case r eports or case series involving 57 patients met the inclusive criteria, of which 10 being in Chinese and 11 in English. The 57 patients being misdiagnosed as TMD were suffering from 20 sorts of diseases, such as pericoronitis of the maxillary third molar(43.86%), nasopharyngeal carcinoma(15.79%), different kinds of tumors(15.97%) in the orofacial region, etc.. Suspected causes of the misdiagnoses could be classified into 7 categories, such as similar clinical manifestations(33.96%), confused chief complaints (26.43%), insufficient understanding of the clinicians(22.64%), etc.. Thirty five articles naming as systematic review in which case reports or case series on misdiagnoses being included were found through intensive searching, 8 in English and 27 in Chinese. They were narrative reviews in light of congeries of same facts without appraising quality of methodology or validity of the case reports or case series.“Review” should be appropriate term for such literatures and it is no need to use a modern term “systematic review” instead. The later term did not raise any new value to the term“review”. Conclusion The misdiagnoses of other diseases as TMD were mainly caused by similarities in symptoms and clinical signs of the diseases with TMD, and insufficient understandings of the clinicians. It is better to use“review” instead of“systematic review” to describe same type of the literatures.

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    Domestic acellular dermal matrix in the treatment of guide bone regeneration the maxillofacial bone defect in planting area of oral performance evaluation
    Chen Hongliang, Zhao Chengchu, Zhao Feng, Zhong Ke, Sun Yong.
    Inter J Stomatol. 2013, 40 (1):  33-36.  DOI: 10.7518/gjkq.2013.01.009
    Abstract ( 1645 )   HTML ( 2 )   PDF(pc) (3103KB) ( 1002 )   Save

    Objective To evaluate the effect of acellular dermal matrix(ADM) on guided bone regeneration(GBR) of the defects of jaw bone. Methods We collected 42 patients with bone defect of the recipient site before implantation visiting the department of stomatology of Chengdu Military Region Hospital of The People’s Liberation Army, and then used domestic ADM GBR to repair jaw bone defect. Examed with X-ray six months postoperatively, and compared the results with that of the GBR preoperatively. Then we implanted in the osteogenesis area, observated the bone formation conditions, made histopathologic study for new bone from implanting. Results 42 patients after review of nonsignificant do not have between -group rejection. Phase of 40 patients underwent surgical process observation osteogenesis result is satisfactory, and planting primary stability is better without residual film. Histology observations show that there are obvious slice of bone formation, because of wound infection. One late osteoblast effect is satisfactory after repeated washing area with antibiotics. The other is failure. Conclusion The effect of GBR with ADM for repairing oral maxillofacial bone defect is definite.

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    Reconstruction after parotidectomy using sternocleidomastoid flap
    Gong Zhongcheng1,Ling Bin1,Keremu Abass1,Yin Xiaopeng1,Liu Hui1,Xia Hui2,Lin Zhaoquan1.
    Inter J Stomatol. 2013, 40 (1):  37-39.  DOI: 10.7518/gjkq.2013.01.010
    Abstract ( 1634 )   HTML ( 0 )   PDF(pc) (6677KB) ( 956 )   Save

    To investigate the outcome of sternocleidomastoid flap applied to reconstruct the defect and prevent Frey’s syndrome after parodidectomy. 24 patients with benign parotid tumors underwent the superficial or deep lobe of parotidectomy and facial nerve preservation. The sternocleidomastoid was employed immediately to repair the defects after parotidectomy in all the patients. Among the 24 cases, no infection and necrosis of the wound and saliva fistula was found. The wounds healed with first intention. Both significant facial deformity and Frey’s syndrome were not observed in the 24 cases followed-up from 6 to 10 months. Therefore, it suggested that the sternocleidomastoid flap could prevent facial depressed deformity and reduce obviously the incidence of Frey’s syndrome after parotidectomy.

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    Fusion of 41 and 42 with lingual cusp deformity: A case report
    Chen Qingyu, Ren Qiang, Dong Dazheng.
    Inter J Stomatol. 2013, 40 (1):  40-41.  DOI: 10.7518/gjkq.2013.01.011
    Abstract ( 1965 )   HTML ( 7 )   PDF(pc) (2858KB) ( 768 )   Save

    Fused teeth are fused from 2 dental germs, frequently seen in deciduous teeth and rarely in permanent teeth. Lingual cusp deformity, mostly occurring in maxillary lateral incisors, arises from malformation of enamel organ which is influenced by external stimulation of dental germs. The report illustrates fused permanent teeth combined with lingual cusp deformity.

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    Research progress on dispersin B
    Chen Shanshan1,2,Qi Xia1,2, Zhao Lei 2.
    Inter J Stomatol. 2013, 40 (1):  42-46.  DOI: 10.7518/gjkq.2013.01.012
    Abstract ( 1551 )   HTML ( 5 )   PDF(pc) (537KB) ( 861 )   Save

    Extracellular polysaccharide, synthesized by the bacteria in the biofilm, is the vital barrier which protect the biofilm against antimicrobial agents and host immune components. Therefore, researches focus on the antibiolfilm agents which exhibit the capability to degrade the extracellular polysaccharide or inhibit its synthesis are of high interest. Dispersin B, a β-N-acetylglucosaminidase produced by the gram-negative periodontal pathogen Actinobacillus actinomycetemcomitans, is reported to show the effect to degrade extracellular polysaccharide recently, and it may be possess the potential of using as an anti-biolfilm agents in clinic. This review will summarize the recent research progress on the structure, mechanism of action and application of dispersin B.

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    Indian hedgehog signaling pathway and remodeling of temporomandibular joint
    Zhang Jie1,Dai Juan1,Wang Meiqing2,Shao Jinling1.
    Inter J Stomatol. 2013, 40 (1):  47-50.  DOI: 10.7518/gjkq.2013.01.013
    Abstract ( 1698 )   HTML ( 0 )   PDF(pc) (410KB) ( 970 )   Save

    Indian hedgehog(Ihh), one of the members of hedgehog protein family, is essential for embryonic development and organ formation. The embryonic growth and pathological changes of temporomandibular joint involve complex processes and attract more and more studies. Recent studies have revealed that Ihh not only participates in the embryonic growth of mandibular condyle but also regulates those processes during post-natal life via the cell-surface receptors patched and smoothened and downstream signal of Gli.

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    Research progress on microRNA-181a and its function in malignant tumors
    He Qianting, Wang Anxun.
    Inter J Stomatol. 2013, 40 (1):  51-54.  DOI: 10.7518/gjkq.2013.01.014
    Abstract ( 1541 )   HTML ( 1 )   PDF(pc) (413KB) ( 620 )   Save

    MicroRNA is a kind of small noncoding RNA that regulates the expression of different genes and plays an important role in cancer cell invasion, migration and metastasis. Recently, research shows that micro- RNA-181a(miR-181a) regulates processes of cell differentiation, the immune system, tumorigenesis, tumor development and prognosis. This review introduced the structure of miR-181a and its function in the tumorigenesis and development, especially the research progress on the oral and maxillofacial malignancy, providing the theoretical basis for further study on miR-181a.

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    The research methods of metagenomic and the application of metagenomic study in the oral microbiota
    Lu Jian, Li Yuhong, Du Minquan.
    Inter J Stomatol. 2013, 40 (1):  55-58.  DOI: 10.7518/gjkq.2013.01.015
    Abstract ( 2390 )   HTML ( 2 )   PDF(pc) (527KB) ( 1636 )   Save

    Metagenomics is the genomes of the total microbiota found in nature. Metagenome libraries were constructed by directly extracting DNA from environmental samples, Such as soil, oceans, human gastrointestinal tract and mouth, etc., and transforming to surrogate host. The libraries were screened for novel bioactive compounds or genes. Therefore, Metagenomics can effectively detect oral microbial community structure, and also can enormously amplified the space of microbial resource utilization and enhanced the opportunity of obtain novel bioactive compounds. This review included the research progress of the methods of metagenomic and the application of metagenomic study in the oral microbiota.

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    Immunopathological role of help T cell-17 in periapical lesions
    Sun Hui, Li Song.
    Inter J Stomatol. 2013, 40 (1):  59-63.  DOI: 10.7518/gjkq.2013.01.016
    Abstract ( 1523 )   HTML ( 2 )   PDF(pc) (466KB) ( 777 )   Save

    Help T cells(Th)-17 cells are identified as a new subset of CD4 positive T cells unrelated to Th1 or Th-2 cells, and several cytokines are involved in regulating their activation and differentiation. Th-17 cells not only play an important role in host defense against extracellular pathogens, but also are associated with the development of autoimmunity and inflammatory response. Although the pathological mechanisms of periapaical lesions are not fully understood, accumulating evidence suggests that the abnormality of innate and adaptive immunity responses play an important role in periapical lesions inflammation. The identification of Th-17 cells can explain some of the anomalies seen in the Th-1, Th-2 axis and the immunopathogenesis of Th-17 cells in development of the periapical lesions. Periapical lesions, which form as a result of a root canal infection, are characterized by a host response to continuous antigenic stimulation in the infected canals and periapical bone destruction. Its pathological mechanisms are closely related to local inflammatory and immunity of periapical tissue. This review will introduce the Th-17 cells, the differentiation and fanctions of Th-17 cells in addition to the relationships between Th-17 cells and periapical lesions..

     

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    Research progress on gene modified nanofibrous scaffolds
    Wang Chi, Zhu Huiyong.
    Inter J Stomatol. 2013, 40 (1):  64-67.  DOI: 10.7518/gjkq.2013.01.017
    Abstract ( 1540 )   HTML ( 0 )   PDF(pc) (410KB) ( 807 )   Save

    The tissue engineering scaffolds with nanostructures are now in widespread use in the research of guided tissue regeneration(GTR), because of the good biocompatibility of the scaffolds and their capacity as the vector of bioactive substances. And how to incorporate the gene into the nanofibrous scaffolds is also an important research field in GTR. This paper reviewed the synthesis and characteristics of the nanofibrous scaffolds, the synthesis of gene modified electrospun nanofibrous membrane, and the study on the way gene was incorporated into and released from the nanofibrous scaffolds. The importance and manner of incorporating gene into the nanofibrous scaffolds and the application prospect of nanofibrous scaffolds were also outlined.

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    Application of psychological intervention models in periodontal disease prevention
    Chen Cuiting, Liang Huanyou, Wu Jian.
    Inter J Stomatol. 2013, 40 (1):  68-71.  DOI: 10.7518/gjkq.2013.01.018
    Abstract ( 1547 )   HTML ( 1 )   PDF(pc) (417KB) ( 1049 )   Save

    Periodontal disease has recently become one of the major public health problems of harming human oral health. Improving the consciousness of self protection is the key factor for prevention of periodontal disease. As the change of the traditional medical model, the new intervention model based on the bio-psycho-social viewpoint shows enormous potential on improving the ability of oral health self-prevention. Promotion the effect on dental health practice and oral health awareness through psychological intervention is widely studied in recent years. The objective of this review is to evaluate the role of psychological intervention models especially the self-effective mode in the treatment and prevention of periodontal disease, and then in order to provide the theoretical basis of periodontal disease comprehensive intervention in the future.

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    Overexpression of the αvβ6 integrin in oralsquamous cell carcinoma is a specific targettor for treatment
    Sang Lei 1,2,Li Hongwei 2,3.
    Inter J Stomatol. 2013, 40 (1):  72-75.  DOI: 10.7518/gjkq.2013.01.019
    Abstract ( 1831 )   HTML ( 0 )   PDF(pc) (444KB) ( 670 )   Save

    Integrin-αvβ6 is a special integrin subtype, which highly express in cancer and healing wound, but did not express in normal tissue and benign tumor. By promoting tumor cell migration and extracellular matrix degradation, activating cytokine transforming growth factor-β1 and inhibiting tumor cell programmed cell death lead to tumor invasion and metastasis. Further study of integrin-αvβ6 expression and function in oral cancer will help to understand the molecular mechanisms of invasion and metastasis, provide oral squamous cell carcinoma treatment with new ideas and methods.

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    Toll-like receptor’s role in intracellular signal pathways and its immune adjustment function
    Hong Lili, Kong Qianying, Wei Xi.
    Inter J Stomatol. 2013, 40 (1):  76-79.  DOI: 10.7518/gjkq.2013.01.020
    Abstract ( 3707 )   HTML ( 14 )   PDF(pc) (461KB) ( 1663 )   Save

    Toll-like receptor(TLR) can trigger intracellular signal transductions and release antimicrobial proinflammatory factors, ultimately activating the host immune response by recognizing the evolutionarily conserved structures on pathogens through ligand-binding domain, which contains leucine-rich repeat motifs. The intracellular signal pathways in pulp cells mediated by TLR have important regulatory effects on body immune responses. Thus, this focus review on the expression of TLR in dental pulp tissues, the TLR signal pathways, and the possible great therapeutic implications in curing pulpitis diseases. By doing so, we aim to perfect the theory of pulpitis pathogenesis, and to provide a new angle for developing medical drugs in controlling the pulpitis problems.

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    Oral alkali production and molecular research progress
    Guo Qiang1,2,Xu Xin1,Zhou Xuedong1.
    Inter J Stomatol. 2013, 40 (1):  80-85.  DOI: 10.7518/gjkq.2013.01.021
    Abstract ( 1977 )   HTML ( 4 )   PDF(pc) (559KB) ( 962 )   Save

    The alkali generation by oral bacteria plays fundamental roles to maintain the balance of microflora and pH of the dental biofilms, and the alkali generation capacity of saliva and plaque was proved to be reversely correlated to the formation of dental caries. Oral alkali generation, which is under the control of multiple environmental factors, is a complex system composed by multiple species and pathways. This paper reviews the major alkali generation pathways in dental biofilms, the correlation of alkali generation to dental caries and the molecular research progress on alkali generation by oral bacteria.

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    The role of gingipain R and protease activated receptors in periodontitis
    Hu Lingjing1,2, Zhang Diya2, Chen Lili1.
    Inter J Stomatol. 2013, 40 (1):  86-89.  DOI: 10.7518/gjkq.2013.01.022
    Abstract ( 1863 )   HTML ( 3 )   PDF(pc) (436KB) ( 779 )   Save

    Porphyromonas gingivalis is recognized as major periodontal pathogens, and can produce gingipain R as one of the main virulence factors. Protease activated receptor is a kind of trans-membrane protein which can recognize many pathogen associated molecular patterns, which can be activated by gingipain R, that is very important in the occurrence and development of periodontitis. This article will review the lasted researches on the composition and biological activities of gingipain R and protease activated receptor, and the role of gingipain R and protease activated receptors in periodontitis.

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    Research progress on Saccharomyces albicans and its related genes
    He Lijia, Lü Hanxian, Lei Yayan.
    Inter J Stomatol. 2013, 40 (1):  90-93.  DOI: 10.7518/gjkq.2013.01.023
    Abstract ( 1601 )   HTML ( 2 )   PDF(pc) (458KB) ( 898 )   Save

    Saccharomyces albicans is an important human fungal pathogen. It causes infections by adhering, invading and damaging to host cells, which depends on the adhesins, the enzyme easy to invade host cells and cell morphology, phenotype of conversion. We will review mainly genes related to the factors of virulence in the pathogenic process.

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    Research progress on pathogenesis of dental fluorosis
    Liu Panlong1,Zhou Hongyan2,Wang Dongmiao3,Mei Yufeng1.
    Inter J Stomatol. 2013, 40 (1):  94-97.  DOI: 10.7518/gjkq.2013.01.024
    Abstract ( 2174 )   HTML ( 5 )   PDF(pc) (393KB) ( 655 )   Save

    The fluorine is a master morbigenous factor of dental fluorosis and plays a role in all stages of enamel formation. The influence of fluoride on amelogenesis, which includes the cell toxicity of fluorine, the influence of enamel matrix protease and the mineralized processes, are reviewed in this article. The correlated mechanism of dental fluorosis was also discussed.

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    Research progress on tooth altered passive eruption
    Zhao Haiyan, Li Jiao, Ding Yi.
    Inter J Stomatol. 2013, 40 (1):  98-101.  DOI: 10.7518/gjkq.2013.01.025
    Abstract ( 3075 )   HTML ( 26 )   PDF(pc) (444KB) ( 1663 )   Save

    Gummy smile always consitutes an unesthetic smile characterized by excessive exhibition of the gums during a full smile. There are several etiologies for gummy smile, and the most commonly overlooked etiology is altered passive eruption(APE). APE is a clinical situation produced by excessive gum overlapping over the enamel limits, resulting in a short clinical crown appearance, which is due to failure in concluding the passive eruption phase. APE can be corrected by periodontal surgery. However, it is essential to establish a differential diagnosis for achieving an esthetic, biological and stable result that satisfies both clinician and patient. This article will review the concept of APE, its classification and epidemiology, clinical diagnosis, treatment modalities and esthetic considerations and also the process of tissue healing.

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    Current situation and progress of evaluating mesiodistal root angulation by panoramic radiography and cone beam computed tomograph
    Liu Taiqi, Zhou Li, Wang Yanmin.
    Inter J Stomatol. 2013, 40 (1):  102-104.  DOI: 10.7518/gjkq.2013.01.026
    Abstract ( 1915 )   HTML ( 1 )   PDF(pc) (378KB) ( 596 )   Save

    A fundamental goal in comprehensive orthodontic treatment is the correct angulation of all teeth in three planes of space, and this calls for proper mesiodistal root angulation. Nowadays the main available methods to evaluate mesiodistal root angulation are panoramic radiography and cone beam computed tomography(CBCT). Each one of them has its own benefit and limitation with different efficacy. This article is to review the current situation and progress of these two methods in evaluating mesiodistal root angulation.

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    Effect of tooth bleaching on the bond strength of orthodontic brackets
    Weng Jiahua, Mai Lixiang, Wang Dawei.
    Inter J Stomatol. 2013, 40 (1):  105-108.  DOI: 10.7518/gjkq.2013.01.027
    Abstract ( 1869 )   HTML ( 4 )   PDF(pc) (394KB) ( 578 )   Save

    As people pursue the beauty of teeth increasingly, tooth bleaching is widely accepted as a routine treatment in treating discolored teeth by most patients. Meanwhile, the recent popularity of tooth bleaching has had a significant impact on the practice of dentistry. While many orthodontic patients have received tooth bleaching treatment before, orthodontic brackets are bonded to the enamel of teeth. The effect of bleaching on the enamel surface morphology and on the bond strength between composite resins and the bleached enamel is worth paying attention by orthodontists. This review will illustrate the effect of tooth bleaching on the bond strength of orthodontic brackets.

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    A review of cleaning methods for removable denture
    Bi Ruiye1, Fan Yi1, Song Dongzhe1, Li Chuanshu2, Luo Yun2.
    Inter J Stomatol. 2013, 40 (1):  109-112.  DOI: 10.7518/gjkq.2013.01.028
    Abstract ( 2108 )   HTML ( 5 )   PDF(pc) (490KB) ( 1063 )   Save

    In the 21st century, with China stepping in an aging society, the number of old people wearing removable dentures increased rapidly. The unique physical and chemical properties of removable denture materials and the peculiar oral environment often lead to oral diseases. Therefore, doctors and patients should draw more attention to denture cleaning. A correct method of denture cleaning plays a significant role in protecting oral supporting tissues. This review has introduced several methods, effectiveness evaluation, application status and prospect in the future of removable denture cleaning. The review aimed to guide doctors and patients to find out an efficient way of denture cleaning in order to reduce oral diseases.

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    Characteristics and clinical application of the T -Scan system
    Yu Tingting, Song Guangbao.
    Inter J Stomatol. 2013, 40 (1):  113-116.  DOI: 10.7518/gjkq.2013.01.029
    Abstract ( 1728 )   HTML ( 6 )   PDF(pc) (425KB) ( 1172 )   Save

    The T-Scan system precisely records the time, force and area of occlusal contact, which also can be dynamically analysed. The T-Scan system can be better used in dental clinical work and research with the products updating and developing. This paper reviewed the characteristics and clinical application of the T-Scan system.

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    Etiology and treatment of Angle class Ⅱ subdivision malocclusion
    Ren Jing, Bai Ding.
    Inter J Stomatol. 2013, 40 (1):  117-120.  DOI: 10.7518/gjkq.2013.01.030
    Abstract ( 1839 )   HTML ( 5 )   PDF(pc) (419KB) ( 1546 )   Save

    Angle class Ⅱ subdivision malocclusion is one of the most common malocclusions in orthodontics. It also is one of the most complicated and difficult situations in treatment. We can use many ways to improve the molar relationship. To achieve the best results, we should always choose methods based on patients’ age, severity, compliance, and so on. This paper summarizes the etiology, clinical features and treatment planning of Angle class Ⅱ subdivision malocclusion.

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    Research progress on Treponema denticola
    Lu Sixian, Wang Qing.
    Inter J Stomatol. 2013, 40 (1):  121-124.  DOI: 10.7518/gjkq.2013.01.031
    Abstract ( 3000 )   HTML ( 28 )   PDF(pc) (462KB) ( 773 )   Save

    Treponema denticola is one of the oral treponema pathogens and has been demonstrated to be involved in periodontal and endodontic diseases, and may play an important role in the progression. The review explored the architectural features, biological characteristics, the virulence factors of Treponema denticola and the relationship between Treponema denticola and periodontal, endodontic diseases.

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    Research progress on detection methods of infected root canals microbial
    Guan Rui, Hou Benxiang.
    Inter J Stomatol. 2013, 40 (1):  125-128.  DOI: 10.7518/gjkq.2013.01.032
    Abstract ( 1631 )   HTML ( 3 )   PDF(pc) (446KB) ( 1158 )   Save

    Pulpitis and apical periodontitis are mainly of mixed infection of anaerobic bacteria infection, one of the most important reason of clinical failed root canal therapy is the continuous infected state of root canal. Clone library, nucleic acid hybridization, 16S rDNA fingerprint and other molecular biological techniques are commonly used to detect the bacteria composition and function. This review presents the molecular methods applied in infectious root canal.

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    Developments on fixation techniques for immature permanent tooth
    He Yi1, Zou Jing2, Yang Ran1.
    Inter J Stomatol. 2013, 40 (1):  129-131.  DOI: 10.7518/gjkq.2013.01.033
    Abstract ( 1648 )   HTML ( 10 )   PDF(pc) (358KB) ( 2099 )   Save

    Traumatic injury of teeth is a common disease in clinic of pediatric dentistry, which often results in the dislocation of young permanent tooth for its immature root. Correct fix technique is the key to insure the successful rate of root development of traumatic young permanent teeth. In recent years, elastic fixations which focus on adhesive technique have gradually replaced the traditional ligation strong fixation. The objective of this article is to review the various treatment methods of the traumatized teeth and its clinical results.

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    Relationship between alveolar cleft bone grafting and facial skeletal growth
    Shao Qinghua, Chen Zhenqi.
    Inter J Stomatol. 2013, 40 (1):  132-134.  DOI: 10.7518/gjkq.2013.01.034
    Abstract ( 1867 )   HTML ( 2 )   PDF(pc) (409KB) ( 1326 )   Save

    Bone grafting of alveolar cleft is an essential step in the sequential management of patients with clefts of lip, alveolus and palate. There is little agreement on the optimal time, which includes primary bone grafting and secondary bone grafting. This is caused by the effects of alveolar bone grafting in different times on facial skeletal growth. This article described the sources of bone graft as well as the relationship between bone grafting and facial skeletal growth from the two bone graft timing.

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    Research progress on saliva proteome analysis in oral disease diagnostics
    Cui Li, Wu Buling.
    Inter J Stomatol. 2013, 40 (1):  135-139.  DOI: 10.7518/gjkq.2013.01.035
    Abstract ( 1883 )   HTML ( 0 )   PDF(pc) (561KB) ( 1391 )   Save

    The development of proteomic techniques provide a robust platform for searching biomarkers in saliva. The article makes a review of the current status of biamarkers in oral squamous cell carcinoma, primary Sj觟gren’s syndrome, periodontal diseases by saliva proteome analysis and existing problems.

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