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20 November 2007, Volume 34 Issue 06 Previous Issue    Next Issue

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Relationship between lymphatic vessel density of tongue cancer and expr ession of vascular endothelial growth factor D and tumor metastasis LI Hui - wen1, HUANG Peng2. Inter J Stomatol. 2007, 34 (06):  399-401.  Abstract ( 1296 )   HTML ( 6 )   PDF（pc） (190KB) ( 852 )   Save Objective To investigate the relationship between lymphatic vessel density（LVD） in tongue squamous cell carcinoma （TSCC）and tumor metastasis. Methods Immunohistochemistry SP method was applied to label the lymphatic vessels of tumors by VEGFR- 3 staining in 62 cases of TSCC, the expression of VEGF- D were analyzed at the same time. Results Of the 62 patients, the positive staining of lymphatic vessels were 56 cases. The functional lymphatic vessels was mainly located in the peri- tumoral areas. No evidence of mature lymphatic vessels was found in the paraneoplastic stroma. The positive expression of VEGF- D was distributed in the cytoplasm of cancer cells. With the increase in the expression of VEGF- D, the LVD of peritumor also increased. Conclusion LVD in TSCC is significantly correlated with neck lymph node metastasis, VEGF- D/VEGFR- 3 pathway can contribute to lymphangiogenesis and lymph node metastasis. Related Articles | Metrics

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Retrospective investigation of clinical application of ERA implant overdentur e on Kennedy Ⅱ dentition defect GENG Jian- ping1,2, MA Quan- sheng2, YAN Wei- qi1. Inter J Stomatol. 2007, 34 (06):  402-404.  Abstract ( 1220 )   HTML ( 6 )   PDF（pc） (29KB) ( 628 )   Save Objective To evaluate the effect of clinical application of ERA implant overdenture on Kennedy Ⅱ dentition defect. Methods 21 cases that were not satisfied with traditional removable denture were applied by ERA implant overdenture. Results 21 cases were satisfied with the new dentures. One implant were failed but repaired quickly and easily. Conclusion ERA implant overdenture is a better choose than with traditional removable denture on Kennedy Ⅱ dentition defect. Related Articles | Metrics

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Clinic effect and exper iences of tr eating tor sional and shift upper anter ior teeth by tooth r eplantation DU Li- juan, GUI He-ming, WEI Wei, HUANG Jie- ying. Inter J Stomatol. 2007, 34 (06):  405-407.  Abstract ( 1007 )   HTML ( 5 )   PDF（pc） (192KB) ( 890 )   Save Objective To observe clinical effects of treating torsional and shift single front teeth by tooth replantation technique. Methods 11 patients with torsional and shift anterial teeth were selected and treated by tooth replantation technique with BAM artificial bone. Periodontal index of treated teeth before and after completing operation 3.6 and 12 months were acquired through clinic examination. Results Periodontal indexes of 11 treated teeth were normal after treating three, six and twelve months. Conclusion Torsional and shift single front teeth can be corrected to normal position by tooth replantation technique with BAM artificial bone. Related Articles | Metrics

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Treatment of dentine hyper sensitivity with Pr ime&Bond RNT bonding agent GONG Hong- jing, GONG Jun, YU Ting- ting, XU Shi- ying，GAN Shu- ping. Inter J Stomatol. 2007, 34 (06):  408-409.  Abstract ( 1398 )   HTML ( 6 )   PDF（pc） (28KB) ( 1219 )   Save Objective To investigate the effective method of treating dentine hypersensitivity. Methods 356 teeth of dentine hypersensitivity in 120 patients were randomly divided into experimental group and controll group. Teeth in experimental group were treated for 3 days by Prime&Bond R NT bonding agent and teeth in controll group were routinely treated for 3 days by herbal desensitizer respectively. The clinical effects were observed in the following 6 months. Results All the effects including immediate effect, effect of 3 months and effect of 6 months of experimental group were better than that of controll group. Conclusion Prime&Bond RNT bonding agent is an ideal desensitizer in the treatment of dentine hypersensitivity. Related Articles | Metrics

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Clinical investigation on dry socket tr eatment by metronidazole - dexamethasone - iodoform paste CUI Inter J Stomatol. 2007, 34 (06):  410-411.  Abstract ( 1366 )   HTML ( 16 )   PDF（pc） (17KB) ( 936 )   Save Objective To detect the effect of dry socket treatment by metronidazole - dexamethasone - iodoform paste. Methods 60 cases with dry socket, divided into two groups of 30 cases each. One group was the test group, the other was the control group. Tooth extraction wounds were normally washed. Metronidazole- dexamethasone - iodoform paste was brushed on the wounds of test group. Iodoform was brushed on the wound of control group. Clinical effect of the two groups was compared. Results In test group, 28 cases gained obvious effect, and 2 gained normal effect. In control group, 10 cases gained obvious effect, and 20 gained normal effect. Test group obtained higher effect ratio（93.33%） compared with control group（33.33%）. Statistical difference in the two group appears（P<0.01）. Conclusion Dry socket treatment by metronidazole - dexamethasone - iodoform paste is recommended in primary hospital with reliability and feasibility. Related Articles | Metrics

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Advances in the r esear ch on Hox genes and tumor genesis XIA Hui, LI Long- jiang. Inter J Stomatol. 2007, 34 (06):  412-415.  Abstract ( 1219 )   HTML ( 5 )   PDF（pc） (26KB) ( 2631 )   Save As a special kind of transcription factor, Hox gene and its expressor play important roles in controlling the embryonic development, cellular growth and differentiation using their specific DNA binding activity. Present studies have showed there is a close relationship between Hox gene and tumor genesis. This article reviews the advances in the research on the structure of Hox gene and correlation between Hox gene and tumor genesis. Related Articles | Metrics

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Histone acetylation and malignant tumor s of head and neck ZHOU Rong- rui, LI Jiang. Inter J Stomatol. 2007, 34 (06):  415-417.  Abstract ( 1204 )   HTML ( 3 )   PDF（pc） (29KB) ( 1020 )   Save The article briefly notices the mechanisms of histone acetylation and deacetylation, and reviews the impact of histone acetylation on genes and proteins associated with different signal transduction pathways, the acetylation status of malignant tumors of head and neck and the inhibiting effect of histone deacetylase inhibitors on tumor cells of head and neck malignancy. Related Articles | Metrics

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The roles of nuclear factor κB in the inflammation- associated cancer YU Tai-ping, LI Yong, WANG Tao. Inter J Stomatol. 2007, 34 (06):  418-420.  Abstract ( 1313 )   HTML ( 4 )   PDF（pc） (26KB) ( 1463 )   Save Nuclear factor κB（NF- κB） is a ubiquitous transcription factor that governs the expression of genes encoding cytokines，chemokines，growth factors, cell adhesion molecules，and anti- apoptotic proteins. It plays an important role, especially in cancer, in the pathogenesis of many diseases. This review briefly discusses about the roles of NF- κB and its feasibility in the therapy of inflammation- associated cancer. Related Articles | Metrics

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Application of br ain functional magnetic r esonance imaging to stomatognathic system YU Chun - hua， ZHANG Fu - qiang. Inter J Stomatol. 2007, 34 (06):  421-423.  Abstract ( 1188 )   HTML ( 4 )   PDF（pc） (28KB) ( 1095 )   Save Functional magnetic resonance imaging is an effective and non - injury technique to investigate the function of brain, which fundamental is blood oxygenation level dependent contrast. Functional magnetic resonance imaging could exactly orient and follow up real- time of changes on brain′s blood and metabolism. Applicaton of functional magnetic resonance imaging to stomatognathic system could offer a way to supply a gap of regulative relationship between central nerve system, maxillofacial muscles, occlusion and temporomandibular joint. Related Articles | Metrics

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New progr ess of per iodontitis and chemokines ZHANG Zhe - dan, SUN Hong- ying. Inter J Stomatol. 2007, 34 (06):  424-426.  Abstract ( 1130 )   HTML ( 5 )   PDF（pc） (27KB) ( 1279 )   Save The chemokines are a kind of small proteins with similar primary structures, which have various biological effect, mostly include chemotaxis of leukocyte, and play a significant regulating effect on the defense and the inflammatory reaction of the body. In recent years, a lot of researches have found that the chemokines play an important role in the immunopathogenesis of periodontitis. Therefore it is important to study the relation of chemokines and periodontitis for prevention, diagnosis, treatment and monitoring of curative effect of periodontitis. Related Articles | Metrics

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Role of junctional epithelium in per iodontal defense r esponse LI Shu- bo, LI De- yi. Inter J Stomatol. 2007, 34 (06):  427-429.  Abstract ( 1714 )   HTML ( 7 )   PDF（pc） (28KB) ( 1444 )   Save The junctional epithelium（JE） is the gingival portion of the dento- gingival tissue interface attached the tooth surface. Its unique location possesses a significant role in tissue homeostasis and defense against microorganisms and their products. Several studies have shown that the tissue structure, rapid renewing and immune response of JE play an active role in the periodontal defense response. The paper is to review the research progress in these fields so as to elucidate the pathogenesis of periodontitis. Related Articles | Metrics

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The application of micro- computed tomogr aphy on per iodontology LIU Zong- xia, LI Shu. Inter J Stomatol. 2007, 34 (06):  430-432.  Abstract ( 1167 )   HTML ( 5 )   PDF（pc） (28KB) ( 3595 )   Save Three- dimensional micro- computed tomography（micro- CT） is a nondestructive, fast, and very precise image procedure, which can take high- resolution three- dimensional images. It is useful for the diagnosis of diseases in the oral region. micro- CT observations can enhance the three- dimensional understanding of periodontal wound healing. It may be useful for three- dimensional evaluation of periodontal regenerative procedures. This review summarized the principal of micro- CT performance and its use in the periodontal disease. Related Articles | Metrics

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The role of advanced glycation end products in per iodontal diseases QI Liu- ying, FU Yun. Inter J Stomatol. 2007, 34 (06):  433-436.  Abstract ( 1154 )   HTML ( 6 )   PDF（pc） (36KB) ( 928 )   Save The advanced glycation end products（AGEs）is a heterogeneous group of compounds of nonenezymatic glycosation reactions. The accumulation of AGEs in diabetic patients′tissue and blood may contribute to the developmemt of diabetic complications. Recently, it has also been found that the enhanced interaction between AGEs and its′receptor was one of the pathogenesises of aggravated periodontal diseases. The objective of this review is to clarify the role of AGEs and its′receptor in periodontal diseases and the correlative mechanism. Related Articles | Metrics

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Toll - like r eceptor 4 in pathogenesis of pulpitis and per iapical per iodontitis and per iodontal disease Inter J Stomatol. 2007, 34 (06):  437-439.  Abstract ( 1134 )   HTML ( 4 )   PDF（pc） (26KB) ( 653 )   Save Pulpitis and periapical periodontitis, periodontal disease are commonly characterized by the chronic inflammation caused by Gram- negative bacteria infection. Lipopolysaccharide（LPS） is a major component of the outer membrane of Gram- negative bacteria. CD14 and Toll - like receptor 4（TLR4） belong to the class of LPS receptors. TLR4 has received much attention as a member of LPS receptors recently and may be a key factor in the pathogenesis of pulpitis and periapical periodontitis and periodontal disease. The article reviews the recent progress of TLR4. Related Articles | Metrics

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Advanced r esear ch of mechanisms of endodontic inter appointment pain BAO Ping- ping1, FAN Bing2, FAN Ming- wen2. Inter J Stomatol. 2007, 34 (06):  440-442.  Abstract ( 1326 )   HTML ( 11 )   PDF（pc） (30KB) ( 1496 )   Save Endodontic interappointment pain is a common complication of root canal therapy. The main causative factors encompass mechanical, chemical, and microbial injury to the periradicular tissues during root canal therapy. In response to the injury, a large mass of chemical mediators are released or activated, and acute inflammation occurs at the periradicular tissues, which leads to the interappointment pain. Knowledge on the mechanisms of interappointment pain can help clinicians to take effective measures for prevention and management. Related Articles | Metrics

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Developments in matrix of dental composite resin WANG Xiao- hui, ZHANG Wen- yun. Inter J Stomatol. 2007, 34 (06):  443-445.  Abstract ( 1558 )   HTML ( 5 )   PDF（pc） (27KB) ( 2444 )   Save Composite resin has been widely used in dental clinic. Resin matrix plays an important role on its property as the main component of composite resin. At present, some new types of resin matrix have been exploited one after the other. This article summarizes the researchs on the aspect. Related Articles | Metrics

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The application of microscopy techniques on evaluating the dentine adhesive inter face QIAN Yun- zhu, YANG Jian- xin. Inter J Stomatol. 2007, 34 (06):  446-448.  Abstract ( 1006 )   HTML ( 4 )   PDF（pc） (26KB) ( 526 )   Save It is well accepted that the main role for strong bonding depends upon the hybrid layer（HL） formed and quality of the interface. Nowadays, lots of microscopy techniques are available for improving the structure between the dentin and adhesive interface and inhibiting the microleakage of the HL. The dentine adhesive interface was evaluated qualitatively and quantitatively by those techniques, which are focused on in this summarization. Related Articles | Metrics

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Advances in the study of mechanisms of malignant tr ansformation of salivary pleomorphic adenoma HU Yu- hua, LI Jiang. Inter J Stomatol. 2007, 34 (06):  449-451.  Abstract ( 1223 )   HTML ( 6 )   PDF（pc） (26KB) ( 903 )   Save Pleomorphic adenoma（PA） is the most common salivary gland neoplasm. The tumor could transform to malignancy as malignant pleomorphic adenoma（MPA）, if the preexisting PA remains for long time or after multiple recurrences. During the malignant transformation, multifactors and multigene alterations are involved. The recent studies demonstrate that cytogenetic alterations, oncogenes, tumor suppressor genes, adhesion molecules and extracellular matrix proteins may play important roles in the process. This article summarized some advances in the mechanisms of the malignant transformation of salivary pleomorphic adenoma. Related Articles | Metrics

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Application of high- throughput technique on detection of tumor marker in or al cancer ZHOU Shang- hui, JIAN Xin- chun. Inter J Stomatol. 2007, 34 (06):  452-454.  Abstract ( 1412 )   HTML ( 5 )   PDF（pc） (26KB) ( 1032 )   Save To screen and identify specific tumor marker is important for the diagnosis, the judgment of therapeutic effect, the detection of recurrence and metastasis, the evaluation of prognosis and the study of pathological mechanism of oral cancer. The traditional detection methods have deficiencies in the aspects of sensitivity and specificity. But with the appearance and development of high- throughput technique, further progress has been made in the study of tumor marker. This paper summarized the application of the high- throughput detection methods of tumor marker in the study of oral cancer. Related Articles | Metrics

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Exploratory development of adipose-derived stem cells on osseocar tilaginous tissue engineering JIAO Guo- hua, ZHANG Zhi - guang. Inter J Stomatol. 2007, 34 (06):  455-457.  Abstract ( 1170 )   HTML ( 4 )   PDF（pc） (29KB) ( 1122 )   Save The study of seeding cells is always a hot spot in tissue engineering. In recent years, the adipose- derived stem cells（ADSCs） are becoming the seeding cell gradually in tissue engineering just because of its several conspicuous advantages. The article drew a review on the following aspects: The overview, the ability of differentiation in vitro and surface markers and the experiments in vivo of ADSCs. Related Articles | Metrics

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Effect of distraction osteogenesis on development of mandible ZHANG Rui, LU Xiao- feng. Inter J Stomatol. 2007, 34 (06):  458-460.  Abstract ( 1278 )   HTML ( 12 )   PDF（pc） (26KB) ( 1760 )   Save Distraction osteogenesis（DO）, which can deminish the trauma of the surgery and decrease the complication and increase the post- operative stability, is increasingly popular. With its application in many children with some syndromes or protal deformities, the effect of DO on the development of children has been paid more and more attention. And this article reviewed the effect of DO on the development of mandible. Related Articles | Metrics

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Factor analysis in successful or al implant and r estor ation ZHU Xiao，TANG Liang. Inter J Stomatol. 2007, 34 (06):  461-463.  Abstract ( 1288 )   HTML ( 4 )   PDF（pc） (28KB) ( 1134 )   Save Oral implant has been widely accepted as a common dental restoration. The diameter and length of the implant, the inserting position for the implant, the analysis of force acting on the implant, the design angle for the abutment, esthetic design of the gingival margin responsive to the implant and the inclination of cusp, are the important factors in determining the key to a successful oral implant and restoration. This article summarized the factors in successful oral implant and restoration. Related Articles | Metrics

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Progress in the study of denture adhesive ZHANG Feng1, LI Xi- ting2, WEI Su- hua1. Inter J Stomatol. 2007, 34 (06):  464-466.  Abstract ( 1284 )   HTML ( 6 )   PDF（pc） (28KB) ( 1536 )   Save Denture adhesives had been recognized as a useful adjunct to denture prosthesis services. The purpose of the article was to summarize the studies concerning the effects of denture adhesives on denture retention, oral environment and oral tissue. Related Articles | Metrics

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Progr ess of investigation on nickel- titanium alloy′s cor rosion r esistance DING Shao- hua, CAI Ping. Inter J Stomatol. 2007, 34 (06):  467-469.  Abstract ( 1359 )   HTML ( 5 )   PDF（pc） (25KB) ( 2265 )   Save Nickel - titanium alloy has special practical value in medicine for its great characteristics of shape memory and super- elasticity. As nickel released from nickel- titanium alloy is cytotoxic, increasing nickel- titanium alloy′s corrosion resistance is becoming important. In this review, it was focused on potentiodynamic test that was the study method of nickel- titanium alloy′s corrosion resistance, electrolyte factor in nickel- titanium alloy′s corrosion, nickel- titanium alloy′s surface configuration on the influence of nickel- titanium alloy′s corrosion resistance. Related Articles | Metrics