Inter J Stomatol ›› 2007, Vol. 34 ›› Issue (06): 412-415.

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Advances in the r esear ch on Hox genes and tumor genesis

XIA Hui, LI Long- jiang.   

  1. Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China
  • Online:2007-11-20 Published:2007-11-20

Abstract:

As a special kind of transcription factor, Hox gene and its expressor play important roles in controlling the embryonic development, cellular growth and differentiation using their specific DNA binding activity. Present studies have showed there is a close relationship between Hox gene and tumor genesis. This article reviews the advances in the research on the structure of Hox gene and correlation between Hox gene and tumor genesis.

Key words: Hox gene, homeobox, biological regulation, tumor


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