Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (3): 401-403.doi: 10.3969/j.issn.1673-5749.2012.03.032

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Glucose transporters and their relationships with oral squamous cell carcinoma

Jiang Huan, Lin Zhiyong.   

  1. Dept. of Stomatology, Provincial Hospital Affiliated to Shandong University, Jinan 250012, China
  • Received:2011-02-16 Revised:2012-03-05 Online:2012-05-01 Published:2012-05-01

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Abstract:

Glucose transporter（GLUT）s are a group of non energy dependent transport proteins in mammalians’ cell membrane, which are the main carriers responsible for transporting glucose into cells. Abnormal GLUTs’ expressions have been reported in many human cancers, and the positive staining of GLUTs is closely related to the genesis, development and prognosis of tumor. GLUTs may be used to develop a new method for early diagnosis and treatment of oral squamous cell carcinoma. This article reviews the research progress on relationships of GLUTs and oral squamous cell carcinoma.

Key words: glucose transporter, oral squamous cell carcinoma, prognosis


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