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01 May 2012, Volume 39 Issue 3 Previous Issue    Next Issue

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Clinical progress and its significance in current apical surgery Wang Xiao. Inter J Stomatol. 2012, 39 (3):  281-285.  DOI: 10.3969/j.issn.1673-5749.2012.03.001 Abstract ( 1356 )   HTML ( 7 )   PDF（pc） (756KB) ( 2257 )   Save Enormous progress has been made and the success of treatment has been improved in apical surgery by using the surgical microscopy, ultrasound equipment, and new materials in recent years. The purpose of this article is to review the clinical progress and significance in current concepts, operating equipments, surgical tech - niques, root-end filling materials, and the application of the guide tissue regeneration in apical surgery. Related Articles | Metrics

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Clinical observation of periapical cyst treatments on 91 anterior teeth Chen Huaili1, Lu Donghui2, Sun Xuemin3. Inter J Stomatol. 2012, 39 (3):  286-289.  DOI: 10.3969/j.issn.1673-5749.2012.03.002 Abstract ( 1052 )   HTML ( 5 )   PDF（pc） (297KB) ( 2034 )   Save Objective The purposes of this study was to investigate the curative effect difference of periapical cyst on anterior teeth treated by root canal therapy and root canal therapy combined apicectomy. Methods The study included clinical cases with periapical cysts on 91 anterior teeth that were treated by root canal therapy. These teeth were randomly assigned to two groups. 44 teeth were treated by apicectomy as experimental group while 47 teeth as controls. All teeth were followed clinically and radiographically examinations for a period ranging from 3 months to 1 year. Results The results of experimental group showed 90.9％ success and the other group was 87.2% success. The difference was not significant（P＞0.05）. Conclusion Root canal therapy is effective in treating the anterior teeth with periapical cysts. Apicectomy should be done only when root canal therapy was ineffective. Related Articles | Metrics

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Hard tissue outcomes of Class Ⅱ division 1 malocclusion with vertical growth pattern before and after treatment Peng Minghui1, Wu Yan2, Kang Jing1, Zhou Jianming1, Li Xiaobing3. Inter J Stomatol. 2012, 39 (3):  290-293.  DOI: 10.3969/j.issn.1673-5749.2012.03.003 Abstract ( 1209 )   HTML ( 3 )   PDF（pc） (167KB) ( 1103 )   Save Objective This study is aimed to evaluate the orthodontic treatment outcomes of patients with Angle Class Ⅱ division 1 malocculsion with vertical growth pattern; and provide experimental results to help to make orthodontic treatment plan and treatments. Methods 38 patients with Angle Class Ⅱ division 1 malocculsion with vertical growth pattern were included in our study. Their pre- and post-treatment cephalometric Xrays were measured. 39 cephalometric items of hard tissue of groups of adolescents and adults were measured before and after treatments, and the different of the measurements between the adolescent and the adult were studied. Results The changes of ANB angle, NA-PA, U1-FH, U1-NA, U1-Ptm, Spr-Ptm, Id-Go between the groups of adolescent and adult were statistically different. The measurements of Pog-Go, Cd-Go, S-Go, N-Me were all increased. While the OP-FH plane was decreased in the adolescent group, the OP-FH plane was increased in the adult group after orthodontic treatment, indicating the clockwise rotated of the adult occlussal plane. Conclusion The orthodontic treatment in adolescent expressed more bony effects, showing that the profiles of Angle Class Ⅱ of adolescents could be improved more than adults. The extrusions of the upper molars were basically within the beneficial range of amount. And with the mandibular ramus growth, these combined effects of molar extrusion and ramus growth could rotate the mandibular plane and occlussal plane anti-clockwisely which benefited to the corrections of Angle Class Ⅱ divison 1 malocclusions with vertical growth pattern and helped to maintain the stability of the treatment results. Our research also suggested that the most effective time to treat Angle Class Ⅱ division 1 malocclusion with vertical growth pattern was during the fast growth period time of adolescent. Related Articles | Metrics

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Extensively damaged molars with curved root canals restored by many posts of porcelain-fused-to-metal crown Li Xin, Lei Shengnan, He Xiangyi. Inter J Stomatol. 2012, 39 (3):  294-296.  DOI: 10.3969/j.issn.1673-5749.2012.03.004 Abstract ( 1011 )   HTML ( 2 )   PDF（pc） (101KB) ( 911 )   Save Objective To investigate the method of keeping patients’residual molar roots with curved root canals restored by many posts of porcelain-fused-to-metal crown. Methods Restored the residual molar roots with curved root canals by many posts of porcelain-fused-to-metal crown. Results 41 extensively damaged molars with curved root canals in 33 patients have been treated by many posts of porcelain-fused-to-metal crown since 2005, and during a 3-year follow-up study, the successful rate is 85.4%. Conclusion It is a simple and effective method to restored extensively damaged molars with curved root canals by many posts of porcelain-fused-tometal crown, but we must master the indications strictly, operate carefully and adopt measures to reduce occlusal force. Related Articles | Metrics

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Study on the development of third molar of the twelve-year-olds in Chengdu through X-ray films Ren Inter J Stomatol. 2012, 39 (3):  297-300.  DOI: 10.3969/j.issn.1673-5749.2012.03.005 Abstract ( 1309 )   HTML ( 3 )   PDF（pc） (357KB) ( 1178 )   Save Objective To investigate the development of third molars of twelve years old teenagers in Chengdu through X -ray films. Methods Randomly selected 449 panoramic radiographs of twelve -year -olds from the database of West China Hospital of Stomatology, Sichuan University, and divided the development degree of third molars into several phrases to analysed the development status according to different genders, the left and right sides, the maxilla and the mandible. Results Most part of the crowns of the third molars of the twelve years old teenagers were mineralized. There was no significant differences between male and female about the development degree of third molars. Mostly, the development of third molars appeared earlier in the mandible than that in the maxillary. The occurrence ratio was 60.69% on the left side and 64.25% on the right side. The abnormal development direction of third molar in the maxillary appeared vertical tilting and in the mandible appeared mesial tilting more frequently. Conclusion The crowns of the twelve-year-olds’third molars were mostly mineralized. The mandible third molars appeared earlier than maxillary ones. Related Articles | Metrics

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Clinical evaluation of combination indirect and direct resin restoration in defective of endodontical treated molars Liang Yifu. Inter J Stomatol. 2012, 39 (3):  301-304.  DOI: 10.3969/j.issn.1673-5749.2012.03.006 Abstract ( 970 )   HTML ( 4 )   PDF（pc） (144KB) ( 1028 )   Save Objective To evaluate clinical effect of combination indirect and direct resin restorations in the defective of endodontical treated molars. Methods A total of 212 endodontical treated molars were selected and randomly divided into two groups. Group A was restored with the indirect resin blocks and dual cure resin filled bonding, group B was restored with the traditional composite fillings. All the restorations were evaluated with United States Public Health Service criterions after 6 months and 18 months treatment. Results After 6 months, the two groups’successful rates of restorations were no significant difference（P＞0.05）. After 18 months, the successful rate of group A and group B were 88.7%（86/97） and 75.0%（72/96） respectively. There was significant difference（ P＜0.05）. Conclusion The indirect restoration was able to avoid adverse factors of resin direct filling, and improve the effect of resin restoration and suited to defects of endodontical treated molars. Related Articles | Metrics

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A cephalometric study on relevant factors of the mesial impaction of mandibular third molars Zhao Shuping, Wang Hu, Li Guo, Ren Jiayin, Wu Wanhong, Yuan Shanshan. Inter J Stomatol. 2012, 39 (3):  305-307.  DOI: 10.3969/j.issn.1673-5749.2012.03.007 Abstract ( 1105 )   HTML ( 3 )   PDF（pc） (118KB) ( 1027 )   Save Objective To evaluate the mechanism of the mesial impaction of mandibular third molars（M3） in adults and the relationship between the mesial impaction or eruption of M3 and the development of maxillary and mandible. Methods 72 subjects who have taken panoramic radiographs and lateral cephalometric radiographs before orthodontic treatments were divided into two groups based on the status of M3: Impaction group and eruption group, and all cephalometric radiographs were analyzed for the two groups. Results Mandibular body length（Go- Po’）, ramal width（W）, mandibular plane angel（MP-FH）, lower anterior face height（ANS-Me） and ramal length/ mandibular length ratio（Co-Go/Co-Po） were significantly difference（P<0.05） in the impaction group than in the eruption group. W and Co-Go/Co-Po were significantly increased（P>0.05） and Go-Po’, ANS-Me, MP-FH were decreased in the impaction group. The impaction and eruption groups did not differ significantly（P<0.05） in respect to Co-Po, Co-Go, U1-L1 angel and ANB angle. Conclusion The mesial impaction or eruption of mandibular M3 seemed to be relevant to the rotational growth of the mandibles and the pattern of facial growth. M3 mesial impactions were more likely to occur in subjects with anterior facial rotation and short facial forms. Related Articles | Metrics

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Effects and mechanism of daidzein on osteodifferentiation of stem cells derived from human exfoliated deciduous teeth Wu Bin1, Xie Chun1, Huang Qian2, Du Xinya1, Huang Jian1, Meng Qiuju1, You Yuehua1. Inter J Stomatol. 2012, 39 (3):  308-311.  DOI: 10.3969/j.issn.1673-5749.2012.03.008 Abstract ( 1016 )   HTML ( 2 )   PDF（pc） (118KB) ( 826 )   Save Objective To investigate the effects and mechanism of daidzein on osteodifferentiation of stem cells derived from human exfoliated deciduous teeth（SHED）. Methods The 3rd passage SHED were incubated with 1, 10, 100 μmol·L－1 daidzein and normal culture medium（control）. Then alkaline phosphatase（AKP） activities were examined at 3, 6 and 9 d, and osteocalcin（OC） in each group was detected at 7, 14 and 21 d. In addition, corebinding factor（cbf）-α1 mRNA expression were detected by RT-PCR at 3, 6 and 9 d after culture. Results 3 d later, AKP activities in SHED were enhanced by 10 μmol·L-1 daidzein（vs. control, P<0.05）, all of three concentrations（ 1, 10, 100 μmol·L-1） daidzein improved AKP activities significantly at 6 and 9 d（vs. control, P<0.001）. Medium and high dose（10, 100 μmol·L-1） daidzein could enhance OC expression in SHED at 14 d after induced culture（vs. control, P<0.001）, and all of the doses daidzein increased OC expression at 21 d（vs. control, P<0.001）. Additionally, RT -PCR showed that 10 and 100 μmol·L -1 daidzein could significantly increase cbf -α1 mRNA expression at the 3rd, while 1 μmol·L－1 daidzein only slightly increase cbf-α1 mRNA expression; at the 6th and 9th d, however, three concentration daidzein increased cbf-α1 mRNA expression obviously. Conclusion Daidzein could stimulate osteodifferentiation of SHED in vitro, and the possible mechanism is its role of promoting the expression of cbf-α1 gene. Related Articles | Metrics

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The osseointegration research of the interface between bone and implant coating by nano-scale titanium thin film Liu Yuanyuan1, Li Guo1, Ren Jiayin1, Zhao Shuping1, Nie Jing2, Wang Hu1. Inter J Stomatol. 2012, 39 (3):  312-316.  DOI: 10.3969/j.issn.1673-5749.2012.03.009 Abstract ( 786 )   HTML ( 2 )   PDF（pc） (435KB) ( 1035 )   Save Objective The aim of this article is to study on the nano-scale materials in the role of implant osseointegration. Methods In this study, nano-scale titanium films were prepared by direct magnetron sputtering on titanium implants. Then the prepared implants coating with the nano-scale thin film are implanted in the bones of animals. The study of the early integration of the bone will be done between the experimented and control groups. Results Analyzed superficial configuration by magnetron sputtering, it showed that nano-scale granular diaphragm formed and it was homogeneous and compact. Dimension of nano-scale granular on lamellar implants was similar with that on columnar implants. However, nano-scale granular was more homogeneous in lamellar ones. The result of animal experiment showed that initial osseointegration increased after implant surgery utilized implants coating by nano-scale titanium thin film. Conclusion Serial animal experimentation manifested that bioactive can be improved after nano-scale titanium thin film formed on the surface of materials. Related Articles | Metrics

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Nano-friction properties research of pure titanium surface by means of nitrogen plasma ion implantation technique Yue Hongchi, Gao Shanshan, Li Yue, Yu Haiyang. Inter J Stomatol. 2012, 39 (3):  317-320.  DOI: 10.3969/j.issn.1673-5749.2012.03.010 Abstract ( 848 )   HTML ( 3 )   PDF（pc） (667KB) ( 860 )   Save Objective To change the composition of titanium surface, and improve the wear resistance. Methods Nitrogen was implanted into the surface of pure titanium using plasma ion implantation, the ion implantation dose was 3×1017 ions·cm－2 and 9×1017 ions·cm－2. The change of surface elements was analyzed by energy-dispersive spectrometry. The hardness of the treated samples was evaluated with micro-hardness tester. The wear resistance was measured by nano-scratch tester. The scratch morphology was analyzed by scanning electron microscope. Results The samples modified by plasma ion implantation showed light golden. The ion implantation dose of 3×1017 ions·cm－2 and 9×1017 ions·cm－2 nitrogen atom content of the samples were 24.08% and 35.83%. The hardness of samples after ion implantation was significantly greater than the samples before ion implantation. The friction coefficient of samples after ion implantation decreased significantly. Conclusion After nitrogen ion implantation, hardness increased significantly, wear resistance of pure titanium can also been improved. Related Articles | Metrics

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Ameloblastic carcinoma, primary type in mandible, with malignant submandibular lymph node metastasi Liu Meiyan1, Zhao Damin2, Geng Ning1, He Huawei3, Yan Cuihua4, He Zhixiu1. Inter J Stomatol. 2012, 39 (3):  321-323.  DOI: 10.3969/j.issn.1673-5749.2012.03.011 Abstract ( 1230 )   HTML ( 3 )   PDF（pc） (255KB) ( 1546 )   Save Ameloblastic carcinoma-primary type is a rare odontogenic epithelial malignant tumor, with few clinical reports. We reported a case of ameloblastic carcinoma -primary type with malignant submandibular lymph nodes. Combined with the literature, we discussed its clinical pathological features, diagnosis, and treatme Related Articles | Metrics

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Antimicrobial peptide LL-37 and its relationship between periodontal disease Su Ruiying1，2, Chen Shanshan1，2, Zhao Lei2. Inter J Stomatol. 2012, 39 (3):  324-327.  DOI: 10.3969/j.issn.1673-5749.2012.03.012 Abstract ( 972 )   HTML ( 3 )   PDF（pc） (143KB) ( 1460 )   Save Periodontal disease is a chronic inflammatory disease that leads to destruction of the periodontium. The abnormal innate immune defense and outcome of periodontal disease is closely related. Cathelicidin is one of endogenous peptide, hCAP-18 and LL-37 is the only member of the cathelicidin family known to exist in human. The former is regarded as an inactive precursor, and the latter is the active mature form. In this review, we emphasize on the hCAP-18, the function of LL-37 and its relationship between periodontal disease. Related Articles | Metrics

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The relationship between Wnt signaling pathway and mechanotransduction in osteocytes Li Xin, Zhu Zhimin. Inter J Stomatol. 2012, 39 (3):  328-331.  DOI: 10.3969/j.issn.1673-5749.2012.03.013 Abstract ( 822 )   HTML ( 3 )   PDF（pc） (140KB) ( 1435 )   Save As one of the most important regulatory systems, Wnt signaling pathway is stimulated very quickly by biomechanical stimulation in osteocytes, which function as key mechanosensory cells in bone. The stimulating procedure is influenced by lots of factors and finally results in regulation of gene expression and bone remolding. This review concludes the research advances concerning the relationship between Wnt signaling pathway and mechanotransduction in osteocytes, and major regulatory factors on the pathway’s stimulation. Related Articles | Metrics

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Research progress on quorum sensing inhibitors in oral microbiol area Wang Shuang1, Zhang Liping1, Xu Yi1，2. Inter J Stomatol. 2012, 39 (3):  332-335.  DOI: 10.3969/j.issn.1673-5749.2012.03.014 Abstract ( 824 )   HTML ( 2 )   PDF（pc） (159KB) ( 1151 )   Save Quorum sensing systems are bacterial cell -to-cell communication systems. Some natural substances and chemical compounds found recently interfere with quorum sensing systems. In this review we highlight inhibitors of acylhomoserine lactone and LuxS/AI-2 mediated quorum sensing in gram-negative bacteria and the corresponding research outcomes in the oral microbiol area. Related Articles | Metrics

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The relationship between trigeminal neuralgia and P2Y receptors Zhao Lili1, Sun Hui1, Wang Yuanyin1, Wang Liecheng2. Inter J Stomatol. 2012, 39 (3):  336-338.  DOI: 10.3969/j.issn.1673-5749.2012.03.015 Abstract ( 881 )   HTML ( 2 )   PDF（pc） (115KB) ( 1032 )   Save As an important neurotransmitter, adenosine triphosphate（ATP） has a wide range of biological effects. A variety of noxious stimulation can cause trigeminal ganglion neurons releasing ATP, and ATP can induce pain through activation of P2 receptors. P2 receptors can be divided into P2X and P2Y receptors. And P2Y receptors expression significantly increased in impaired trigeminal ganglion neurons. In here, the research progress of the relevance of ATP and the expression of P2Y receptor, the signal transduction mechanisms of P2Y receptor which in TG, and the transduction of P2Y receptor on nerve injury pain signal were reviewed. Related Articles | Metrics

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Research progress on the molecular mechanisms for the degeneration of Meckel’s cartilage Liu Yong, Yang Rongtao, Li Zubing. Inter J Stomatol. 2012, 39 (3):  339-341.  DOI: 10.3969/j.issn.1673-5749.2012.03.016 Abstract ( 1001 )   HTML ( 8 )   PDF（pc） (111KB) ( 1173 )   Save Meckel’s cartilage which is derived from the first branchial arch plays an important role during the development and growth of the mandible and also the morphology of malleus and incus. As a supporting bar for the mandibular early development, the intermediate region of Meckel’s cartilage gradually degenerated after birth. This paper aimed to review the molecular mechanisms of the degeneration of Meckel’s cartilage. Related Articles | Metrics

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Research progress on fluoride -resistant strains of Streptococcus mutans Wu Yeke, Hu Tao. Inter J Stomatol. 2012, 39 (3):  342-345.  DOI: 10.3969/j.issn.1673-5749.2012.03.017 Abstract ( 834 )   HTML ( 1 )   PDF（pc） (142KB) ( 935 )   Save As a caries-preventive agent, fluoride could probably lead to fluoride-resistant strains of Streptococcus mutans（S.mutans） with its wide application in the daily life. In order to understand the cariogenic changes in virulence of the fluoride-resistant strains of S.mutans, scholars conducted various studies concerning their ultrastructure, adhesion, acid resistance, acid production and demineralization ability, as well as cariogenic related genes and other molecular biological characteristics. This article was committed to review the research progress in recent years. Related Articles | Metrics

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Research progress on relationship between Vitamin A and oral clefts Li Jingtao, Shi Bing. Inter J Stomatol. 2012, 39 (3):  346-348.  DOI: 10.3969/j.issn.1673-5749.2012.03.018 Abstract ( 898 )   HTML ( 5 )   PDF（pc） (106KB) ( 1182 )   Save The relationship between Vitamin A and oral clefts has been constantly highlighted in the researches on clefts etiology, especially the teratogenic effect of hypervitaminosis A. In this article, the classification of Vitamin A, epidemiology and mechanism of hypervitaminosis A induced clefts was reviewed. Related Articles | Metrics

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Revascularization treatment of immature permanent teeth with necrotic pulp Liu Jiajia1, Qin Man2. Inter J Stomatol. 2012, 39 (3):  349-352.  DOI: 10.3969/j.issn.1673-5749.2012.03.019 Abstract ( 1158 )   HTML ( 5 )   PDF（pc） (128KB) ( 1939 )   Save In recent years, with the development of life science, materials science and related disciplines, people have had a new understanding about the immature permanent teeth’s ability to regenerate. The regenerative endodontics as a new treatment of pulp necrosis, which may bring more desirable outcomes than the conventional treatment, has become a research focus. As one of the regenerative treatments, pulp revascularization has advantages such as convenience, relatively low cost, lack of immune rejection and ethical issues involved and has gained attention. This article will review the history and the development of this method, as well as its application in the treatment of pulp necrosis of immature permanent teeth. Related Articles | Metrics

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Research progress on peri-implantitis relationship in polymorphisms of interleukin-1 gene, periodontitis and smoking Liu Qiong, Huang Jiansheng. Inter J Stomatol. 2012, 39 (3):  353-356.  DOI: 10.3969/j.issn.1673-5749.2012.03.020 Abstract ( 1022 )   HTML ( 3 )   PDF（pc） (139KB) ( 1192 )   Save Peri-implantitis are inflammatory lesions which effect the tissue near the implant in function. It is the main cause which dues to failed implant. Its clinical manifestations are fistula, bleeding or suppuration on probing, bone loss in the X-ray picture. There are many reasons for peri-implantitis, such as bacterial contamination, overloading. Besides biomechanical factors, genetic susceptibility, patients who have a history of periodontitis and smoking status are more at risk for peri-implant diseases. Most scholars think that smoking and a history of periodontitis may affect implant success rates, but they do not agree on the relationship between genotype and periimplantitis. This article is an overview about the polymorphisms in the interleukin-1（IL-1） gene, the history of periodontitis and smoking status, researching their relations with peri-implantitis. Related Articles | Metrics

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Relationship between dental erosion and gastroesophageal reflux disease Huang He1, Fa Yonghong2, Yang Yongjin2, Cai Xingwei2. Inter J Stomatol. 2012, 39 (3):  357-359.  DOI: 10.3969/j.issn.1673-5749.2012.03.021 Abstract ( 1148 )   HTML ( 6 )   PDF（pc） (140KB) ( 1054 )   Save Dental erosion is the irreversible loss of dental hard tissue by chemical process in the absence of bacteria. Gastroesophageal reflux disease（GERD） is a common gastrointestinal disturbance disease, which considered to be one of the main causes to dental erosion. This review aimed to explore the pathogenesis and mechanism of dental erosion, in addition to explain the clinical manifestation, prevention and treatment of dental erosion. Dental erosion is considered to be one of the most important extra-oesophageal manifestations in patients with GERD. The diagnosis and treatment of dental erosion need to coordinate the department of digestive and the department of stomatology. Early diagnosis of GERD and suppress acid reverse flow through the lifestyle changes and drugs, and prevent dental erosion and further loss of teeth mineral and damage are very important. Related Articles | Metrics

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Insulin -like growth factor - Ⅰ and its regulation on the development of mandibular condylar cartilage Jiang Liting, Gao Yiming. Inter J Stomatol. 2012, 39 (3):  360-364.  DOI: 10.3969/j.issn.1673-5749.2012.03.022 Abstract ( 919 )   HTML ( 2 )   PDF（pc） (174KB) ( 1317 )   Save The postnatal condylar cartilage lives in complex mechanical micro-circumstances, and its growth and modification depends on proliferation and differentiation of condylar chondrocytes. Insulin-like growth factor（IGF）- Ⅰ is one of the important growth factors during growth and development in the condylar cartilage. At the cellular level, IGF-Ⅰexerts its biological actions through the binding and activation of IGF-Ⅰ , and its bioefficacy is modulated by IGF binding proteins（IGFBP）. IGF-Ⅰ induces variety cellular responses, including cell proliferation, differentiation, and aopotosis, promoting matrix synthesis and taking part in intercellular signal mechanotransduction. The article reviews IGF - Ⅰ and its receptor, IGFBP and its role and mechanism on the development of postnatal mandibular condylar cartilage. Related Articles | Metrics

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Application of nasal endoscopy to orbital fractures Lü Jun, Liao Xuejuan. Inter J Stomatol. 2012, 39 (3):  365-367.  DOI: 10.3969/j.issn.1673-5749.2012.03.023 Abstract ( 832 )   HTML ( 1 )   PDF（pc） (136KB) ( 992 )   Save Transcutaneous or transconjunctival approaches offer fine surgery field to the repair of orbital fractures, yet remaining invasively surgical scar. Nasal endoscopy achieves great success in diagnosis and reduction of isolated orbital wall fractures, as well as better view of fractures of posterior orbital wall fractures and orbital contents entrapped into sinus, owing to accessible and minimally invasive surgical approaches and excellent illumination. Endoscopic sinus approach associated with transcutaneous or transconjunctival excisions represent advantages in repairing fractures of naso-orbital-ethmoidal complex. Here we review the diagnostic value, strengths and weaknesses, clinical indications, surgical technique, implant materials and fixation materials involving in nasal en - doscopy repairing orbital fractures. Related Articles | Metrics

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The progress in the relationship between oral pathogenic bacterium and epithelial cell junction Zhang Liping1, Wang Shuang1, Xu Yi1，2. Inter J Stomatol. 2012, 39 (3):  368-372.  DOI: 10.3969/j.issn.1673-5749.2012.03.024 Abstract ( 1045 )   HTML ( 3 )   PDF（pc） (177KB) ( 1078 )   Save Epithelial cell junction plays an important role in maintaining normal physiological function and resisting microbial invasion. In this paper, epithelial cell junction’s type, location, structure, function; relationships between abnormal expression of epithelial cell junction proteins and certain diseases; researches on non -oral pathogenic bacterium in epithelial cell junction and the studies of oral pathogenic bacterium in epithelial cell junction are reviewed. Related Articles | Metrics

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Research progress on platelet-rich fibrin Yang Shimao1, Wang Mingguo2. Inter J Stomatol. 2012, 39 (3):  373-375.  DOI: 10.3969/j.issn.1673-5749.2012.03.025 Abstract ( 959 )   HTML ( 4 )   PDF（pc） (140KB) ( 2499 )   Save Platelet-rich fibrin（PRF） is a source of autogenic neotype biomaterial, which is rich in cytokine and growth factors, and is called new generation of platelet concentrates. The molecular constitution of PRF is similar to nature blood clot, and to provide location with migration, proliferation, and differentiation for rhagiocrine cell. Recently, many researchers use PRF as graft on the sinus floor elevation in dental implantation and win well results. This article reviewed PRF and its application on sinus floor elevation in dental implantation. Related Articles | Metrics

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Effects of parathyroid hormone and parathyroid hormone related protein in the related cells of tooth repair Liu Lin1, Wang Shengyu2, Yuan Xiaoping1. Inter J Stomatol. 2012, 39 (3):  376-379.  DOI: 10.3969/j.issn.1673-5749.2012.03.026 Abstract ( 823 )   HTML ( 4 )   PDF（pc） (144KB) ( 1042 )   Save As the unavoidable concurrent disease in orthodontic treatment, root resorption has captured the attention of orthodontists. The parathyroid hormone（PTH） and parathyroid hormone related protein（PTHrP） have been used in orthodontic treatment by scholars in order to find the mechanism of tooth resorption and tooth repair which are complicated. This paper reviews the basic effect of PTH and PTHrP, also summarizes the machnism of PTH and PTHrP affect the cementoblast, alveolar bone cells and periodontal ligament cells. Related Articles | Metrics

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Research progress on dental pulp stem cells differentiation Gou Wenting, Ye Ling, Tan Hong. Inter J Stomatol. 2012, 39 (3):  380-383.  DOI: 10.3969/j.issn.1673-5749.2012.03.027 Abstract ( 1463 )   HTML ( 16 )   PDF（pc） (140KB) ( 2048 )   Save Dental pulp stem cell（DPSC） is a kind of adult stem cells with high proliferative capacity, self-renewal property and multilineage differentiation potential, which are capable to differentiate into several lineages under specific stimuli and play an important role in dental pulp repair and tooth regeneration. This article will review the research progress of DPSC differentiation. Related Articles | Metrics

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Advances in clinical administration and basic research of orthodontic pain Qiao Hu1, Zhu Yongjin2, Zhou Hong1. Inter J Stomatol. 2012, 39 (3):  384-389.  DOI: 10.3969/j.issn.1673-5749.2012.03.028 Abstract ( 897 )   HTML ( 4 )   PDF（pc） (222KB) ( 1559 )   Save Orthodontic pain is the most common symptom, which affects not only the clinical effect of orthodontic treatment, but also patients’intention to receive orthodontic treatment. Reports revealed that 95% of orthodontic patients had suffered varying degrees of pain. How to eliminate or release orthodontic pain, to ensure the effectiveness of orthodontic treatment, and to improve the oral health care quality effectively have become the concerns among orthodontists and patients. In this review, we summarized the clinical feature and possible mechanisms of orthodontic pain, meanwhile compared the different pain relief schemes commonly used in clinical case, and analyzed the peripheral mechanism involved in orthodontic pain for practical protocol of clinical analgesia. Related Articles | Metrics

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Application of rapid prototyping technology in prosthodontics Qian Chao, Sun Jian. Inter J Stomatol. 2012, 39 (3):  390-393.  DOI: 10.3969/j.issn.1673-5749.2012.03.029 Abstract ( 818 )   HTML ( 2 )   PDF（pc） (131KB) ( 1417 )   Save Rapid prototyping technology is a technology which designs three-dimensional models by the computer aided and rapidly manufactures production parts. As its advantages of the work without any additional tooling or machining, fast, flexible and highly integrated, the technology has been used in industrial manufacturing. Now it has taken a wide application in dentistry, from the previous model production, to being applied directly into the physiological functions of components. Especially the application in prosthodontics has become a hot spot. Different kinds of dental restorations can be fabricated by a variety of rapid prototyping methods and tools directly, which is opening up a new digital production field in prosthodontics. The paper describes the summary and prospect of rapid prototyping technology using in design and production aspects of the dental prosthesis, oral and maxillofacial prosthesis and functional gradient materials. Related Articles | Metrics

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Micro RNAs and oral premalignant lesions Zhu Xiaohan, Fu Ji, Chen Qianming, Zeng Xin. Inter J Stomatol. 2012, 39 (3):  394-396.  DOI: 10.3969/j.issn.1673-5749.2012.03.030 Abstract ( 857 )   HTML ( 2 )   PDF（pc） (136KB) ( 928 )   Save Micro RNAs are small non-coding RNAs that mediate gene expression at the post-transcriptional level by degrading or repressing target messenger RNAs. The current studies showed micro RNAs were related to many oral cancers and played a key role in the tumorigenesis of some oral premalignant lesions. The relationship of micro RNAs and oral premalignant lesions was reviewed in the article. Related Articles | Metrics

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A retrospective analysis of applications on protraction facemask for maxillary hypoplasia in cleft lip and palate patients Chen Zhengxi, Chen Zhenqi. Inter J Stomatol. 2012, 39 (3):  397-400.  DOI: 10.3969/j.issn.1673-5749.2012.03.031 Abstract ( 840 )   HTML ( 2 )   PDF（pc） (129KB) ( 848 )   Save Cleft lip and palate is one of the most common congenital craniofacial defects. At present, the optimal approach to treat it is operation. Maxillary retrusion which could be seen in cleft lip and palate patients after palate repair is characterized by the presence of concave profile, anterior crossbite and even psychological problems. Maxillary protraction can cause maxilla to move forward, inhibit mandible to move forward and improve the concave profile by stimulating 4 sutures in maxilla through a facemask. This article is to provide an overview of maxillary protraction in cleft lip and palate patients. Related Articles | Metrics

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Glucose transporters and their relationships with oral squamous cell carcinoma Jiang Huan, Lin Zhiyong. Inter J Stomatol. 2012, 39 (3):  401-403.  DOI: 10.3969/j.issn.1673-5749.2012.03.032 Abstract ( 837 )   HTML ( 3 )   PDF（pc） (136KB) ( 686 )   Save Glucose transporter（GLUT）s are a group of non energy dependent transport proteins in mammalians’ cell membrane, which are the main carriers responsible for transporting glucose into cells. Abnormal GLUTs’ expressions have been reported in many human cancers, and the positive staining of GLUTs is closely related to the genesis, development and prognosis of tumor. GLUTs may be used to develop a new method for early diagnosis and treatment of oral squamous cell carcinoma. This article reviews the research progress on relationships of GLUTs and oral squamous cell carcinoma. Related Articles | Metrics

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Effect of mechanical function and clinical results of porcelain laminate restoration based on different tooth preparation designs Liu Jingying, Liu Xiaoming. Inter J Stomatol. 2012, 39 (3):  404-407.  DOI: 10.3969/j.issn.1673-5749.2012.03.033 Abstract ( 891 )   HTML ( 7 )   PDF（pc） (128KB) ( 949 )   Save Because of the esthetic appeal, biocompatibility and adherence to the physiology of minimal-invasive dentistry, porcelain laminate veneers have now become a restoration of choice. The ultimate clinical results of porcelain laminate veneers could be affected by many factors, and the type of preparation designs was straightly related to the esthetic effect and the final achievement ratio. The type of preparation designs was one of the important warrants for good clinic results. The paper reviewed the types and the effects of preparation to the mechanical function and restoration results of porcelain veneers, in order to provide references for clinic applications. Related Articles | Metrics

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Research progress on engineering tissue stem cells Xu Fengwei, Liu Zhonghao. Inter J Stomatol. 2012, 39 (3):  408-411.  DOI: 10.3969/j.issn.1673-5749.2012.03.034 Abstract ( 824 )   HTML ( 2 )   PDF（pc） (135KB) ( 676 )   Save Research in regenerative medicine is developing at a significantly quick pace. Engineering tissue bone provides a new method for bone defect, and becomes an interesting research. As very important element of engineering tissue bone, stem-cells play an important role. Stem cells are undifferentiated cells with the capability to regenerate into one or more committed cell lineages. The present review gives classification and characteristic of stem-cells differenting into bone cells. Related Articles | Metrics

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Aesthetic research progress on dental midline deviation Guo Congcong, Zhou Chen, Bao Baicheng. Inter J Stomatol. 2012, 39 (3):  412-415.  DOI: 10.3969/j.issn.1673-5749.2012.03.035 Abstract ( 961 )   HTML ( 11 )   PDF（pc） (140KB) ( 1165 )   Save Facial symmetry is an important factor of facial aesthetics. In the study of smile aesthetics, the concordance of dental midline and facial midline is closely related to evaluation of smile aesthetics. Dental midline deviation is quite common among general people. As a result, dental midline deviation is often the patient’s chief complaint, and dentofacial midline discrepancy is considered as an important diagnostic factor in orthodontic treatment planning. This article will make a review on the epidemiology situation, etiology classification of dental midline deviation, as well as its diagnosis, treatment and its influence on smile aesthetics. Related Articles | Metrics

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Research progress on the role of autophagy in the malignant transformation of oral lichen planus Chang Zhen1, Li Ronglin1, Li Chunyang2. Inter J Stomatol. 2012, 39 (3):  416-420.  DOI: 10.3969/j.issn.1673-5749.2012.03.036 Abstract ( 901 )   HTML ( 3 )   PDF（pc） (167KB) ( 1346 )   Save Oral lichen planus（OLP） is a common inflammatory disease of oral mucosa, which is easy to recurrent and has malignant tendency. The precise etiology and pathogenesis about OLP is unknown. Autophagy is a highly conserved phenomenon in eukaryotic cells, as one type of programmed cell death, which plays an important role in the maintenance of inter-cellular environment homeostasis. At present, there is no report about the relationship between autophagy and the development and malignant transformation of OLP. In this article, the correlation between autophagy and OLP has been discussed. Related Articles | Metrics