Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (3): 336-338.doi: 10.3969/j.issn.1673-5749.2012.03.015

Previous Articles     Next Articles

The relationship between trigeminal neuralgia and P2Y receptors

Zhao Lili1, Sun Hui1, Wang Yuanyin1, Wang Liecheng2.   

  1. 1. Dept. of Oral and Maxillofacial Surgery, Hospital of Stomatology, Anhui Medical University, Hefei 230032, China; 2. Dept. of Physiology, School of Basic Medicine, Anhui Medical University, Hefei 230032, China
  • Received:2011-04-19 Revised:2012-02-15 Online:2012-05-01 Published:2012-05-01

RichHTML

2

PDF (PC)

1036

Abstract:

As an important neurotransmitter, adenosine triphosphate（ATP） has a wide range of biological effects. A variety of noxious stimulation can cause trigeminal ganglion neurons releasing ATP, and ATP can induce pain through activation of P2 receptors. P2 receptors can be divided into P2X and P2Y receptors. And P2Y receptors expression significantly increased in impaired trigeminal ganglion neurons. In here, the research progress of the relevance of ATP and the expression of P2Y receptor, the signal transduction mechanisms of P2Y receptor which in TG, and the transduction of P2Y receptor on nerve injury pain signal were reviewed.

Key words: adenosine triphosphate, P2Y receptor, G-protein coupled receptor, trigeminal neuralgia


TrendMD: 
[1] Qin Zhang,Ping Gong. Advancements in receptor activity-modifying protein-1 for osteogenesis [J]. Inter J Stomatol, 2019, 46(1): 30-36.
[2] Xu Peng, Chen Chuanjun. The progress of relationship between primary trigeminal neuralgia and herpes simplex virus infection [J]. Inter J Stomatol, 2016, 43(2): 220-222.
[3] Xiang Zhenting, Zheng Xiaohui. Local drug injection to treat idiopathic trigeminal neuralgia [J]. Inter J Stomatol, 2016, 43(1): 38-.
[4] Li Peng1, Tang Wei2, Chen Yao3.. Anatomical character of pterygopalatine fossa and advancement of related technique [J]. Inter J Stomatol, 2012, 39(4): 526-529.
[5] LIU An -dong, LEI Jie, WANG Yuan-yin, ZHOU Jian. Research progress of trigeminal neuralgia and P2X receptors [J]. Inter J Stomatol, 2010, 37(02): 174-174～177.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .