Int J Stomatol

Inter J Stomatol ›› 2007, Vol. 34 ›› Issue (03): 185-187.

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The Distribution and Function of Defensins in Periodontium

LI Ya- ling, TAO Ren- chuan.   

  1. Dept. of Periodontology and Oral Medicine, Stomatology Hospital of Guangxi Medical University, Nanning 530021, China
  • Online:2007-05-20 Published:2007-05-20

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Abstract:

Defensins are small cationic peptides. These peptides have been reported to function as antimicrobial agents against Gram- negative and Gram- positive bacteria, fungi and viruses. Periodontal disease is caused by bacteria, and bacterial plaque is the initial factor of periodontal disease. In this review, we describe the distribution and function of defensins in periodontium, and emphasize on their characterization during the process of periodontal disease.

Key words: defensin, periodontal disease, subgingival plaque


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