Int J Stomatol ›› 2021, Vol. 48 ›› Issue (2): 192-197.doi: 10.7518/gjkq.2021029

• Reviews • Previous Articles     Next Articles

Research progress on hydrogels for pulp regeneration

Cao Chunling(),Han Bing,Wang Xiaoyan()   

  1. Dept. of Cariology and Endodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China
  • Received:2020-07-02 Revised:2020-11-16 Online:2021-03-01 Published:2021-03-17
  • Contact: Xiaoyan Wang;
  • Supported by:
    National Natural Science Foundation of China(81771061);National Natural Science Foundation of China(81400562)


Hydrogel is a soft, biocompatible polymer network system that can be used as a scaffold in tissue engineering. Using the principles of tissue engineering, dental pulp stem cells cultured in vitro can be implanted into biocompatible, degradable scaffolds, and induced to form pulp-dentin complex and dental pulp-like tissue. Hydrogel scaffolds simulate the extracellular microenvironment and transmit signal molecules, representing a promising material for pulp regeneration. This study reviews the applications of hydrogels with different compositions and properties for pulp regeneration.

Key words: hydrogel, scaffold, pulp regeneration, tissue engineering

CLC Number: 

  • R782.2

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