Int J Stomatol

Int J Stomatol ›› 2020, Vol. 47 ›› Issue (1): 90-94.doi: 10.7518/gjkq.2020002

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An overview of bioactive glasses/chitosan composites for biomedical applications

Zou Jundong,Liu Dingkun,Yang Nan,Wang Mi,Liu Zhihui()   

  1. Dept. of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2019-04-10 Revised:2019-09-16 Online:2020-01-01 Published:2020-01-01
  • Contact: Zhihui Liu E-mail:liu_zh@jlu.edu.cn
  • Supported by:
    This study was supported by Key Science and Technology Research and Development Project of Jilin Science and Technology Department(20180201056YY);Key Science and Technology Achievements Transformation Project of Jilin Provincial Science and Technology Department(20180201056YY);Changchun Science and Technology Bureau Changchun City Campus (School, Institute) Cooperation Special(17DY024)

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Abstract:

Inorganic bioactive glass (BG) and natural chitosan (CS) are applied widely in biomedical fields due to their biological properties. Recent studies showed that compared with individual components, composites have optimised mechanical and biological properties, indicating their enormous potential for future development. This paper briefly introduces the physical and chemical properties of BG and CS and emphasises the recent studies on various applications of the BG/CS composites in bone tissue engineering, controlled release of drugs and molecules and implant dressing based on literature.

Key words: bioactive glass, chitosan, bone tissue engineering, controlled release, implant dressing

CLC Number: 

  • R318.08

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Tab 1

Mechanical properties of cortical and trabe-cular bone compared with BG and CS"

材料类型 压缩强度/MPa 杨氏模量/MPa 孔隙率/%
骨密质 130~200 3 000~30 000 3~12
骨松质 0.1~20.0 20~26 940 50~90
BG（45S5 BG） 14~500 35 000~100 000 30~80
CS 0.005~89.480 35.50~88.98
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