Int J Stomatol

Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (3): 340-345.doi: 10.7518/gjkq.2018.03.018

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Research progress on synthetic nanosilicates in bone tissue engineering

Liang Xinyu, Shi Jiabo, Chen Wenchuan, Zhu Zhimin   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Prosthodontics 1, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2017-07-12 Revised:2017-12-22 Published:2018-05-08

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Abstract: Synthetic nanosilicates are clay nanoparticles that have a cellular-level size, distinct charged and layered structure, and high surface-to-volume ratio, which enhances their interactions with proteins, cells, and polymers. Recently, researchers have focused on the implications of using synthetic nanosilicates in bone tissue engineering to understand their physicochemical and biological properties. The scope of this review includes the well-established use of synthetic nanosilicates for the adjustment of cell functions during bone tissue engineering. The interactions of synthetic nanosilicates with growth factors enable controlled delivery, and their mechanical or biological properties are enhanced when they interact matrix materials. This review is useful to future studies on synthetic nanosilicates.

Key words: synthetic nanosilicates, bone tissue engineering, osteoinduction, carrier, matrix material, synthetic nanosilicates, bone tissue engineering, osteoinduction, carrier, matrix material

CLC Number: 

  • R783.1

TrendMD: 
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