Int J Stomatol

Int J Stomatol ›› 2015, Vol. 42 ›› Issue (6): 720-723.doi: 10.7518/gjkq.2015.06.024

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Research progress on the Mg-based material scaffolds and its application in animal bone tissue engineering

Zheng Jianmao, Mao Xueli, Ling Junqi.   

  1. Dept. of Conservative Dentistry and Endodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2014-12-07 Revised:2015-04-08 Online:2015-11-01 Published:2015-11-01

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Abstract:

Mg-based scaffold, as a novel biodegradable metallic material that inherently offers suitable mechanical properties and osteoconductivity, is proven safe in medical science. Mg-based scaffolds, including scaffolds with surface modification, Mg alloy scaffolds, and porous Mg scaffolds, can reduce corrosion, enhance the proliferation and adhesion of bone marrow stem cells, and promote angiogenesis. In animal models, Mg-based scaffolds can improve bone healing. Thus, these Mg-based scaffolds can potentially be applied to bone tissue engineering.

Key words: Mg-based materials, biodegradable metallic materials, bone tissue engineering, bracket

CLC Number: 

  • R 783.1

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