Int J Stomatol

Inter J Stomatol ›› 2019, Vol. 46 ›› Issue (1): 55-61.doi: 10.7518/gjkq.2019.01.010

• Reviews • Previous Articles     Next Articles

Research progress on salivary markers for diagnosis of aggressive periodontitis

Zhuo Yang,Shengdan Zhang,Chengcheng Liu,Yi Ding()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-01-14 Revised:2018-04-11 Online:2019-01-01 Published:2019-01-11
  • Contact: Yi Ding E-mail:yiding2000@126.com
  • Supported by:
    This study was supported by National Program on Key Basic Research Project (973 Program)(2013CBA0-1700);Natural Science Foundation of China(81371149);Natural Science Foundation of China(81600871)

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Abstract:

Aggressive periodontitis is a specific form of periodontal disease with a high rate of progression and patterns of tissue destruction. This infection mostly affects young individuals and exhibits familial aggregation. Given the ability of salivary biomarkers to indicate the condition of soft tissues, bones and microorganisms in oral, salivary biomarkers may possess the potential to diagnosis and monitor aggressive periodontitis. Obtaining saliva can be low cost, noninvasive, simple and comfortable. Salivary biomarkers can be applied to early diagnosis and real-time monitoring of aggressive periodontitis. In this review, we summarise the research progression on salivary markers for aggressive periodontitis diagnosis to provide new ideas for diagnosis of such infection.

Key words: aggressive periodontitis, saliva, microbes, oxidative stress, protein

CLC Number: 

  • R781.4 +2

TrendMD: 
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