Int J Stomatol

Inter J Stomatol ›› 2017, Vol. 44 ›› Issue (6): 664-668.doi: 10.7518/gjkq.2017.06.008

• Periodontitis • Previous Articles     Next Articles

Research on the role of inflammaging in diabetes mellitus-associated periodontitis

Zhang Peng1, Ding Yi2, Wang Qi1   

  1. 1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;
    2. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2017-04-10 Revised:2017-08-15 Online:2017-11-01 Published:2017-11-01
  • Supported by:
    This study was supported by National Natural Science Foundation of China(81200794) and International Cooperation Project of Chengdu Municipal Science and Technology Bureau(2015-GH02-00035-HZ).

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Abstract: Diabetes mellitus-associated periodontitis is a common age-related disease. However, methods for the prevention and treatment of this disease need further development. Inflammaging has been recently raised as an important factor in the occurrence and development of diabetic complications. This paper reviewed the relevant literature about the research and mechanism on the role of inflammaging in diabetes mellitus-associated periodontitis and provided the new approach for pathogenesis and treatment of periodontitis inpatients with diabetes.

Key words: diabetes mellitus-associated periodontitis, inflammaging, oxidative stress, inflammatory cytokines, DNA damage, autophagy

CLC Number: 

  • R781.4

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