Int J Stomatol

Inter J Stomatol ›› 2016, Vol. 43 ›› Issue (1): 18-.doi: 10.7518/gjkq.2016.01.005

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The effects of Liuwei Dihuang Pill to interleukin-6 and estrogen in gingival crevicular fluid before and after treatment of periodontal during the postmenopausal women

Ren Qiang1, Li Chunnian2, Yang Dongru2   

  1. 1. Dept. of Stomatology, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science & Technology, Baotou 014010, China; 2. Dept. of Oral Medicine, Stomatological Hospital of Hebei Medical University, Hebei Key Laboratory of Oral Medicine, Shijiazhuang 050017, China
  • Received:2015-03-09 Revised:2015-09-15 Online:2016-01-01 Published:2016-01-01

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Abstract:

Objective To investigate the influence of Liuwei Dihuang Pill(LWDHP) treating periodontal during the postmenopausal women. Methods Twenty-seven postmenopausal female patients with moderate to advanced chronic periodontal disease were chosen, and were divided into two groups randomly. Basic treatment group: patients didn’t take any medicine, only accept initial therapy of periodontal. LWDHP treatment group: initial therapy of periodontal with oral took LWDHP 2 months. Collected and detected the concentration of interleukin(IL)-6, estrogen(E2) in gingival crevicular fluid(GCF) before and after treatment. Results A significant decrease was shown in the concentrations of GCF-IL-6 of two groups after therapy compared to before treatment on 2nd month, it had statistically differences(P<0.01), there were no statistically significant differences between the two groups(P>0.05). Basic treatment group increased the concentrations of GCF-E2 of two groups after therapy compared to before treatment on 2nd month. Basic treatment group had no statistically significant difference(P>0.05), LWDHP treatment group had statistically significant differences(P<0.01). Conclusion Periodontal initial therapy can make the concentration of IL-6 in GCF decrease and improves periodontal condition. The concentration of E2 in GCF could be increased by LWDHP.

Key words: periodontal, Liuwei Dihuang Pill, estrogen, interleukin-6

CLC Number: 

  • R 781.4

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