Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (5): 674-677.doi: 10.7518/gjkq.2013.05.031

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Relationship between survivin and oral diseases

Li Qian1, Pan Yaping1,2.   

  1. 1. Dept. of Oral Biology, School of Stomatology, China Medical University, Shenyang 110002, China; 2. Dept. of Periodontics, The Affiliated Hospital of Stomatology, China Medical University, Shenyang 110002, China
  • Received:2012-10-24 Revised:2013-04-15 Online:2013-09-01 Published:2013-09-01

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Abstract:

Survivin, a member of the inhibitor of apoptosis protein family, functions as a regulator of mitosis and cell-death decisions. Survivin affects the initiation and progression of diseases by interfering with cell proliferation and apoptosis. In recent years, the relationship between survivin and oral diseases has attracted considerable research attention. This article focuses on the biological functions of survivin as well as relevant research progress in oral cancer, periodontal diseases, and salivary gland development.

Key words: survivin, mitosis, apoptosis, oral cancer, periodontal diseases, salivary gland developmen


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