Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (3): 371-374.doi: 10.7518/gjkq.2013.03.025

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Application of mesenchymal stem cell in tumor targeted therapy

Xu Yuanming, Fan Mingwen, Yang Xuechao   

  1. The State Key Laboratory Breeding Base of Basic Science of Stomatology（Hubei-MOST） & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2012-06-16 Revised:2013-02-21 Online:2013-05-01 Published:2013-05-01

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Abstract:

Mesenchymal stem cells（MSC） display inherent tumor-tropic properties and differentiation ability with a pro- or anti-tumorigenic effect. In this review, we overviewed the research advances of the biological characteristics of MSC, the interaction of MSC and tumor cells and the tumor targeted therapy based on modified MSC.

Key words: mesenchymal stem cell, tumor, targeted therapy, gene therapy


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