Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (3): 334-338.doi: 10.7518/gjkq.2013.03.016

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Lipoxin A4 and inflammatory diseases

Wang Xueying, Guan Weiqun   

  1. Dept. of Stomatology, The Affiliated Union Hospital of Fujian Medical University, Fuzhou 350001, China
  • Received:2012-08-13 Revised:2012-10-25 Online:2013-05-01 Published:2013-05-01

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Abstract:

Lipoxin A4（LXA4） is one of the products of arachidonic acid metabolic pathway. It displays promising bioaction of anti-inflammatory, as well as pro-resolving. In this review, the author focus on the synthesis, function, and metabolism of lipoxin and the research development of LXA4 and its analogs, LXA4 and inflammatory, then to explore the possibilities of its application in oral mucosal disease research.

Key words: lipoxin, inflammatory, resolution


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