Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (6): 775-777.doi: 10.3969/j.issn.1673-5749.2012.06.019

Previous Articles     Next Articles

Expression and its significance of phospholipase C -γ1 in tumors

Zhu Dongwang, Zhong Laiping, Zhang Zhiyuan.   

  1. Dept. of Oral and Maxillofacial-Head and Neck Tumor Surgery, School of Medicine, The Ninth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200011, China; Shanghai Key Laboratory of Stomatology, Shanghai 200011, China
  • Received:2012-03-04 Revised:2012-08-13 Online:2012-11-01 Published:2012-11-01

RichHTML

2

PDF (PC)

406

Abstract:

Metastasis is the main cause of death in the patients with cancers, which is associated closely with cellular proliferation and invasion. The overexpression of phospholipase C-γ1 can increase the ability of cancerous cells to invade and metastasize, so it maybe a therapeutic potential to counteract the metastatic dissemination. This paper reviewed the literatures about the significance of phospholipase C-γ1 in the motility of cells, increasing the ability of cancerous cells to invade and metastasize, and the mechanisms of tumor migration and invasion.

Key words: phospholipase C-γ1, tumor, metastasis, invasion


TrendMD: 
[1] Zhou Jinkuo,Zhang Jinhong,Shi Xiaojing,Liu Guangshun,Jiang Lei,Liu Qianfeng. Influences of long noncoding RNA small nucleolar RNA host gene 22 on the cell proliferation, invasion and migration of oral squamous carcinoma cells by regulating microRNA-27b-3p [J]. Int J Stomatol, 2024, 51(1): 52-59.
[2] Wu Jiamin,Xia Bin,Yang Hefeng,Xu Biao.. Research progress on cancer-associated fibroblasts in the tumor microenvironment of oral squamous cell carcinoma [J]. Int J Stomatol, 2023, 50(6): 711-717.
[3] Liu Jianglong, Tuerdi Maimaitituxun. Progress of contrast-enhanced ultrasound in the diagnosis of cervical lymph node metastasis from oral squamous cell carcinoma [J]. Int J Stomatol, 2023, 50(5): 514-520.
[4] Zhao Lingfan, Zhou Yang, Ye Xinxin, Zhang Qiang.. Poorly differentiated mucoepidermoid carcinoma of the parotid gland after renal transplantation: a case report [J]. Int J Stomatol, 2023, 50(4): 419-422.
[5] Zhang Chaoying,Li Yining,Gong Jiaxing,Wang Huiming. Interpretation of the 2022 classification of head and neck tumors by the World Health Organization: odontogenic and maxillofacial bone tumors [J]. Int J Stomatol, 2023, 50(3): 263-271.
[6] Sheng Nanning,Wang Jue,Nan Xinrong. Research progress on mechanism and treatment of sex-determining region Y box 9 in oral squamous cell carcinoma [J]. Int J Stomatol, 2023, 50(3): 314-320.
[7] Li Tan,Liang Xin-hua.. Role of discoidin domain receptor 1 in the regulation of malignant tumor progression and therapy [J]. Int J Stomatol, 2023, 50(2): 230-236.
[8] Luo Wanyi,Han Juxi,Zhou Xuedong,Peng Xian,Zheng Xin. Research progress on the mechanism of Fusobacterium nucleatum promoting the initiation and development of colorectal cancer [J]. Int J Stomatol, 2023, 50(1): 52-60.
[9] Li Shan,Chen Linlin. Treatment of patients with negative cervical lymph nodes in maxillary squamous cell carcinoma [J]. Int J Stomatol, 2021, 48(4): 444-449.
[10] Li Ming,Yuan Zhenying,Nan Xinrong. Correlation between the depth of invasion measured by magnetic resonance imaging and cervical lymph node metastasis in patients with tongue squamous cell carcinoma [J]. Int J Stomatol, 2021, 48(3): 312-317.
[11] Gan Jianguo,Gao Pan,Wang Xiaoyi. Research progress on the relationship between circulating tumor cells and oral squamous cell carcinoma [J]. Int J Stomatol, 2021, 48(2): 205-212.
[12] Fu Shijin,Zeng Kan,Li Xin,Yang Jing,Wang Chenglin,Ye Ling. Preliminary study on osteoprotegerin/receptor activator of nuclear factor-κB ligand expression in mandible and femur on site selectivity of bone metastasis of lung cancer cells [J]. Int J Stomatol, 2020, 47(5): 538-546.
[13] Cui Yujia,Sun Jianxun,Zhou Xuedong. Progress for understanding the effect of berberine in oral diseases [J]. Int J Stomatol, 2020, 47(1): 115-120.
[14] Zeng Kan,Li Xin,Wang Chenglin,Yang Jing,Ye Ling. Effects of bone microenvironment cells on tumor bone metastasis [J]. Int J Stomatol, 2020, 47(1): 95-101.
[15] Yue Shijing,Qing Yifan,Lin Jie,Han Bo. Effects of spleen tyrosine kinase and its related signalling pathways on the development of head and neck tumors and their mechanisms [J]. Int J Stomatol, 2019, 46(4): 442-449.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .