Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (3): 324-327.doi: 10.3969/j.issn.1673-5749.2012.03.012

Previous Articles     Next Articles

Antimicrobial peptide LL-37 and its relationship between periodontal disease

Su Ruiying1，2, Chen Shanshan1，2, Zhao Lei2.   

  1. 1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China; 2. Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2011-01-07 Revised:2012-02-03 Online:2012-05-01 Published:2012-05-01

RichHTML

3

PDF (PC)

1440

Abstract:

Periodontal disease is a chronic inflammatory disease that leads to destruction of the periodontium. The abnormal innate immune defense and outcome of periodontal disease is closely related. Cathelicidin is one of endogenous peptide, hCAP-18 and LL-37 is the only member of the cathelicidin family known to exist in human. The former is regarded as an inactive precursor, and the latter is the active mature form. In this review, we emphasize on the hCAP-18, the function of LL-37 and its relationship between periodontal disease.

Key words: LL-37, antimicrobial peptide, cathelicidin, periodontal disease, innate immunity


TrendMD: 
[1] Liu Lin,Zhou Jieyu,Wu Yafei,Zhao Lei. Application of probiotic ecological regulation in prevention and treatment of periodontal diseases [J]. Int J Stomatol, 2020, 47(2): 131-137.
[2] Chen Yanyan,Peng Xian,Zhou Xuedong,Cheng Lei. Application of quantitative light-induced fluorescence in the clinical treatment of caries and periodontal diseases [J]. Int J Stomatol, 2019, 46(6): 699-704.
[3] Cheng Guoping,Ding Yi,Guo Shujuan. Progress in electrospun fibres as periodontal drug delivery systems [J]. Int J Stomatol, 2019, 46(5): 565-570.
[4] Zhu Bowen,Chen Limei,Guo Zhuling. Review of NLRP3 inflammasomes in periodontal diseases [J]. Int J Stomatol, 2019, 46(4): 450-455.
[5] Shujuan Guo, Qian Liu, Yi Ding. A brief introduction of the new classification scheme for periodontal and peri-implant diseases and conditions [J]. Int J Stomatol, 2019, 46(2): 125-134.
[6] Zhengmou Dong,Rui Liu,Luchuan Liu,Xiujie Wen. Research progress on the seed cells in periodontal tissue regeneration [J]. Inter J Stomatol, 2019, 46(1): 48-54.
[7] Changchang Ye, Lei Zhao, Dongqing Wang, Xiaoli Wang, Haiyan Wang, Meng You, Ping Huang, Yafei Wu. The treatment strategy of periodontal disease during pregnancy [J]. Inter J Stomatol, 2018, 45(5): 501-508.
[8] Jing Wang,Yan Wang,Chuandong Wang,Ruijie Huang,Yan Tian,Wei Hu,Jing Zou. Application of liquorice and its extract to the prevention and treatment of oral infections and associated diseases [J]. Inter J Stomatol, 2018, 45(5): 546-552.
[9] Miao Di, Wu Yafei. Treponema denticola chymotrypsin-like protease complex and its pathogenic features [J]. Inter J Stomatol, 2017, 44(6): 674-678.
[10] Liang Jing, Wang Kai, Wu Jiayuan. Research progress on CD24 in stomatology [J]. Inter J Stomatol, 2017, 44(5): 608-613.
[11] Xie Chengjia, Ge Shaohua.. Progress review of diagnosis and treatment of cemental tear [J]. Inter J Stomatol, 2017, 44(3): 315-319.
[12] Lü Jiao, Zhao Wenfeng. Research progress on nonsurgical periodontal therapy [J]. Inter J Stomatol, 2016, 43(5): 594-598.
[13] Qu Qian1, Fang Fuchun1, Wu Buling1,2. Role of long noncoding RNA in periodontal disease and oral cancer [J]. Inter J Stomatol, 2016, 43(1): 62-.
[14] Du Linling, Feng Juan.. Human neutrophil peptide-1-3 and its relationship with caries risk [J]. Inter J Stomatol, 2015, 42(6): 699-702.
[15] Wu Leng, Wang Jun, Zhao Lei, Wu Yafei.. Nucleotide-binding oligomerization domain-like-receptor family pyrin domain-containing 3 inflammasomes and the relationship between it and periodontal diseases [J]. Inter J Stomatol, 2015, 42(6): 710-714.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .