国际口腔医学杂志 ›› 2017, Vol. 44 ›› Issue (5): 587-590.doi: 10.7518/gjkq.2017.05.019
房栗, 王翔, 王文梅
Fang Li, Wang Xiang, Wang Wenmei.
摘要: 吸烟对呼吸系统、消化系统、生殖系统、感官系统等多系统造成危害,可导致各种疾病的发生、发展。为了研究烟草与人类疾病的相关性,吸烟相关疾病模型的建立及完善越来越受到人们的关注,目前吸烟相关疾病模型主要包括体外吸烟细胞模型、动物吸烟模型和临床样本吸烟模型3类。本文就吸烟疾病模型的发展过程和研究进展作一综述。
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[1] 世界卫生组织. 世界卫生组织2013年全球烟草流行报告[R]. 日内瓦: 世界卫生组织, 2013:12-15. World Health Organization. WHO report on the global tobacco epidemic, 2013[R]. Geneva: World Health Organization, 2013:12-15. [2] Zhang L, Ren JW, Wong CC, et al. Effects of ciga-rette smoke and its active components on ulcer for-mation and healing in the gastrointestinal mucosa[J]. Curr Med Chem, 2012, 19(1):63-69. [3] Hecht SS. Cigarette smoking: cancer risks, carcino-gens, and mechanisms[J]. Langenbecks Arch Surg, 2006, 391(6):603-613. [4] Muhlbock O. Carcinogenic effects of cigarette smoke in mice[J]. Ned Tijdschr Geneeskd, 1955, 99(31): 2276-2278. [5] Li Y, Pu G, Chen C, et al. Inhibition of FHL1 inhi-bits cigarette smoke extract-induced proliferation in pulmonary arterial smooth muscle cells[J]. Mol Med Rep, 2015, 12(3):3801-3808. [6] Bulmanski Z, Brady M, Stoute D, et al. Cigarette smoke extract induces select matrix metalloprotei-nases and integrin expression in periodontal ligament fibroblasts[J]. J Periodontol, 2012, 83(6):787-796. [7] Wang X, Qian YJ, Zhou Q, et al. Caspase-12 silencing attenuates inhibitory effects of cigarette smoke extract on NOD1 signaling and hBDs expression in human oral mucosal epithelial cells[J]. PLoS One, 2014, 9 (12):e115053. [8] Peña N, Carrillo D, Muñoz JP, et al. Tobacco smoke activates human papillomavirus 16 p97 promoter and cooperates with high-risk E6/E7 for oxidative DNA damage in lung cells[J]. PLoS One, 2015, 10(4):e0123029. [9] Nagaraj NS, Zacharias W. Cigarette smoke condensate increases cathepsin-mediated invasiveness of oral carcinoma cells[J]. Toxicol Lett, 2007, 170(2):134-145. [10] Thorne D, Wilson J, Kumaravel TS, et al. Measure-ment of oxidative DNA damage induced by mainstream cigarette smoke in cultured NCI-H292 human pulmo-nary carcinoma cells[J]. Mutat Res, 2009, 673(1):3-8. [11] Semlali A, Witoled C, Alanazi M, et al. Whole ciga-rette smoke increased the expression of TLRs, HBDs, and proinflammory cytokines by human gingival epi-thelial cells through different signaling pathways[J]. PLoS One, 2012, 7(12):e52614. [12] Wang WM, Ye P, Qian YJ, et al. Effects of whole cigarette smoke on human beta defensins expression and secretion by oral mucosal epithelial cells[J]. Tob Induc Dis, 2015, 13(1):3. [13] He ZH, Chen P, Chen Y, et al. Comparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysema[J]. Tob Induc Dis, 2015, 13(1):6. [14] Luo YL, Zhang CC, Li PB, et al. Naringin attenuates enhanced cough, airway hyperresponsiveness and airway inflammation in a guinea pig model of chronic bronchitis induced by cigarette smoke[J]. Int Immuno-pharmacol, 2012, 13(3):301-307. [15] Polverino F, Doyle-Eisele M, McDonald J, et al. A novel nonhuman primate model of cigarette smoke-induced airway disease[J]. Am J Pathol, 2015, 185 (3):741-755. [16] Giorgetti AP, César Neto JB, Casati MZ, et al. Ciga-rette smoke inhalation influences bone healing of post-extraction tooth socket: a histometric study in rats[J]. Braz Dent J, 2012, 23(3):228-234. [17] Benatti BB, César-Neto JB, Gonçalves PF, et al. Smo-king affects the self-healing capacity of periodontal tissues. A histological study in the rat[J]. Eur J Oral Sci, 2005, 113(5):400-403. [18] Allais L, Kerckhof FM, Verschuere S, et al. Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut[J]. Environ Microbiol, 2016, 18(5):1352-1363. [19] Camlin NJ, McLaughlin EA, Holt JE. Through the smoke: use of in vivo and in vitro cigarette smoking models to elucidate its effect on female fertility[J]. Toxicol Appl Pharmacol, 2014, 281(3):266-275. [20] Park MG, Ko KW, Oh MM, et al. Effects of smoking on plasma testosterone level and erectile function in rats[J]. J Sex Med, 2012, 9(2):472-481. [21] Higuchi A, Ito K, Dogru M, et al. Corneal damage and lacrimal gland dysfunction in a smoking rat model [J]. Free Radic Biol Med, 2011, 51(12):2210-2216. [22] Ross CL, Galloway-Phillipps N, Armstrong PC, et al. Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach[J]. BMJ Open, 2015, 5(1):e005750. [23] Ertugrul AS, Sahin H, Dikilitas A, et al. Gingival cre-vicular fluid levels of human beta-defensin-2 and ca-thelicidin in smoker and non-smoker patients: a cross-sectional study[J]. J Periodontal Res, 2014, 49(3):282-289. [24] Qian YJ, Wang X, Gao YF, et al. Cigarette smoke modulates NOD1 signal pathway and human β defensins expression in human oral mucosa[J]. Cell Physiol Biochem, 2015, 36(2):457-473. [25] Bhutani M, Pathak AK, Fan YH, et al. Oral epithelium as a surrogate tissue for assessing smoking-induced molecular alterations in the lungs[J]. Cancer Prev Res(Phila), 2008, 1(1):39-44. |
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