国际口腔医学杂志

国际口腔医学杂志 ›› 2023, Vol. 50 ›› Issue (2): 210-216.doi: 10.7518/gjkq.2023021

• 综述 • 上一篇    下一篇

黄酮类化合物对口腔微生物的影响及其机制

陈艺菲1(),张滨婧1,冯淑琦1,徐锐1,杨淑娴1,李雨庆2()   

  1. 1.口腔疾病研究国家重点实验室;国家口腔疾病临床医学研究中心;四川大学华西口腔医学院 成都 610041
    2.口腔疾病研究国家重点实验室;国家口腔疾病临床医学研究中心;四川大学华西口腔医院 成都 610041
  • 收稿日期:2022-05-12 修回日期:2022-09-09 出版日期:2023-03-01 发布日期:2023-03-14
  • 通讯作者: 李雨庆
  • 作者简介:陈艺菲，学士，Email：1677935971@qq.com
  • 基金资助:
    国家自然科学基金(32170046);四川省国际合作项目(2022-YFH0048)

Effects of flavonoids on oral microorganisms and its mechanism

Chen Yifei1(),Zhang Binjing1,Feng Shuqi1,Xu Rui1,Yang Shuxian1,Li Yuqing2()   

  1. 1.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Di-seases & West China School of Stomatology, Sichuan University, Chengdu 610041, China
    2.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2022-05-12 Revised:2022-09-09 Online:2023-03-01 Published:2023-03-14
  • Contact: Yuqing Li
  • Supported by:
    National Natural Science Foundation of China(32170046);International Research and Development Program of Sichuan(2022YFH0048)

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摘要：

黄酮类化合物是一种广泛存在于植物中的天然有机化合物。由于黄酮类化合物具有优良的抗菌作用，近年来关于黄酮类化合物对变异链球菌、牙龈卟啉单胞菌、白色念珠菌等口腔微生物的影响及其机制的研究逐渐增加，显示多种黄酮类化合物对于口腔致病微生物具有抑制作用，在口腔疾病的防治及口腔健康保健方面具有研究价值。本文主要总结了黄酮类化合物对口腔微生物的作用及其机制，评价了黄酮类化合物在防治口腔疾病及口腔卫生保健中的应用价值。

关键词: 黄酮类化合物, 口腔微生物, 抗菌作用, 口腔疾病预防

Abstract:

Flavonoids are natural organic compounds widely existed in plants. In recent years, there has been an increasing amount of research on the effects and processes of flavonoids on oral microbes such as Streptococcus mutans, Porphyromonas gingivalis, and Candida albicans, due to their strong antibacterial activity. It demonstrates that a variety of flavonoids have an inhibitory impact on oral pathogenic bacteria and may be useful in the prevention and treatment of oral illnesses and oral health care. This review summarized the effects and mechanism of flavonoids on oral microorga-nisms and evaluated the application value of flavonoids in prevention and treatment of oral diseases and oral health care.

Key words: flavonoids, oral microorganism, antimicrobial effect, oral disease prevention

中图分类号: 

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