国际口腔医学杂志

国际口腔医学杂志 ›› 2021, Vol. 48 ›› Issue (5): 609-613.doi: 10.7518/gjkq.2021087

• 综述 • 上一篇    下一篇

吸烟影响口腔微环境及其在龋病进展中的作用

范宇(),程磊()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院牙体牙髓病科 成都 610041
  • 收稿日期:2020-12-24 修回日期:2021-05-22 出版日期:2021-09-01 发布日期:2021-09-10
  • 通讯作者: 程磊
  • 作者简介:范宇,学士,Email： 1186529727@qq.com
  • 基金资助:
    国家自然科学基金面上项目(81870759)

Smoking affects the oral microenvironment and its role in the progression of dental caries

Fan Yu(),Cheng Lei()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-12-24 Revised:2021-05-22 Online:2021-09-01 Published:2021-09-10
  • Contact: Lei Cheng
  • Supported by:
    National Natural Science Foundation of China(81870759)

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摘要：

流行病学研究表明：吸烟与龋病的发生发展密切相关。现代龋病病因学指出：口腔微环境的改变,包括唾液的流率、缓冲能力、成分等,以及口腔微生物组成的改变,导致产酸耐酸菌成为优势菌,脱矿-再矿化平衡被打破,导致了龋病的形成。此外,社会经济地位、口腔保健意识等其他龋病相关因素也会影响龋病的发生发展。研究显示：吸烟会对口腔微环境产生直接和间接的影响,进而促进龋病的发生。本文将从这一方面对吸烟的致龋机制作一综述。

关键词: 吸烟, 龋病, 唾液, 口腔微生物, 尼古丁

Abstract:

Numerous epidemiological studies report a close relationship between smoking and the occurrence of dental caries. Modern caries etiology shows that changes in the oral microenvironment including saliva flow rate, buffer capacity, composition, and oral microbial composition causes acid-forming and acid-fast bacteria to dominate. Consequently, the balance of demineralization and remineralization is broken, leading to the occurrence of caries. Other caries-related factors such as socioeconomic status and oral-health awareness also affect the occurrence and development of caries. Studies show that smoking exerts direct and indirect effects on the oral microenvironment, thereby promoting the occurrence of caries. The aim of our review is to summarize the effect of smoking on dental caries from this aspect.

Key words: smoking, dental caries, saliva, oral microorganism, nicotine

中图分类号: 

  • R781.1
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