国际口腔医学杂志 ›› 2013, Vol. 40 ›› Issue (1): 135-139.doi: 10.7518/gjkq.2013.01.035

• 综述 • 上一篇    

唾液蛋白质组学在口腔疾病诊断中的研究进展

崔力  吴补领   

  1. 南方医科大学口腔医学院口腔内科学教研室; 南方医院口腔治疗中心  广州 510515
  • 收稿日期:2012-02-16 修回日期:2012-11-05 出版日期:2013-01-01 发布日期:2013-01-01
  • 通讯作者: 吴补领,Tel:020-62787149
  • 作者简介:崔力(1986—),男,广东人,硕士
  • 基金资助:

    广东省人才引进课题基金资助项目(Z1030270)

Research progress on saliva proteome analysis in oral disease diagnostics

Cui Li, Wu Buling.   

  1. Dept. of Oral Medicine, College of stomatology,Southern Medical University, Guangzhou 510515, China; Medical center of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
  • Received:2012-02-16 Revised:2012-11-05 Online:2013-01-01 Published:2013-01-01

摘要:

近年蛋白质组技术的发展为利用唾液寻找疾病标志物提供了更稳健的平台。本文就唾液蛋白质组分析技术研究口腔鳞状细胞癌、原发性舍格伦综合征、牙周病等疾病标志物现况和当前存在的问题作一综述。

关键词: 蛋白质组技术, 唾液诊断, 标志物, 口腔鳞状细胞癌, 原发性舍格伦综合征

Abstract:

The development of proteomic techniques provide a robust platform for searching biomarkers in saliva. The article makes a review of the current status of biamarkers in oral squamous cell carcinoma, primary Sj觟gren’s syndrome, periodontal diseases by saliva proteome analysis and existing problems.

Key words: proteomic analysis, saliva diagnostics, biomarker, oral squamous cell carcinoma, primary Sjögren’s syndrome