Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (1): 80-85.doi: 10.7518/gjkq.2013.01.021

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Oral alkali production and molecular research progress

Guo Qiang1，2 , Xu Xin1 , Zhou Xuedong1.   

  1. 1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China; 2. Dept. of Oral Biology, College of Dentistry, University of Florida, Florida 32611, USA
  • Received:2012-06-26 Revised:2012-11-05 Online:2013-01-01 Published:2013-01-01

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Abstract:

The alkali generation by oral bacteria plays fundamental roles to maintain the balance of microflora and pH of the dental biofilms, and the alkali generation capacity of saliva and plaque was proved to be reversely correlated to the formation of dental caries. Oral alkali generation, which is under the control of multiple environmental factors, is a complex system composed by multiple species and pathways. This paper reviews the major alkali generation pathways in dental biofilms, the correlation of alkali generation to dental caries and the molecular research progress on alkali generation by oral bacteria.

Key words: Dental caries, Dental plaque, Oral bacteria, Alkali production


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