Int J Stomatol ›› 2021, Vol. 48 ›› Issue (5): 592-599.doi: 10.7518/gjkq.2021069

• Reviews • Previous Articles     Next Articles

Volatile sulfur compounds and its role in the management of intra-oral halitosis

Huang Peiqing(),Peng Xian,Xu Xin()   

  1. State Key Laboratory of Oral Disease & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2021-01-03 Revised:2021-04-01 Online:2021-09-01 Published:2021-09-10
  • Contact: Xin Xu;
  • Supported by:
    General Program of National Natural Science Foundation of China(81771099)


Intra-oral halitosis is one of the most frequent complaints of patients seeking oral treatment, which is mainly produced due to the breakdown of certain amino acids by anaerobic bacterium, followed by the release of volatile sulfur compounds (VSCs). It is generally considered that VSCs are closely related with tongue coating and periodontitis. This review summarizes the source of VSCs and the progress on the treatments of intra-oral halitosis, which are aimed at controlling dental plaque or reacting directly with VSCs. Research advancement in this field provides not only evidence for halitosis therapy, but new ideas and methods of halitosis treatment.

Key words: intro-oral halitosis, volatile sulfur compounds, oral anaerobic bacteria, dental plaque biofilm

CLC Number: 

  • R781

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