Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (3): 351-357.doi: 10.7518/gjkq.2018.03.020

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Research progress on nucleoside drugs against herpes virus

Ji Ning, Zhao Hang, Zeng Xin, Chen Qianming   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2017-10-09 Revised:2018-01-30 Published:2018-05-08
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81621062, 81500860).

Abstract: Herpes virus can cause many diseases, such as keratitis, cold sores, herpes zoster, genital herpes, and encephalitis, etc. Aciclovir and related nucleoside analogues are gold standard molecules for treatment of herpetic diseases in clinical over the past decades. Here, the recent progress of anti-herpes virus nucleoside agents are summarized in this review, including structure characteristic, antiviral mechanism and clinical application.

Key words: herpes virus, nucleoside drugs, mechanism

CLC Number: 

  • R97

TrendMD: 
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