Inter J Stomatol ›› 2007, Vol. 34 ›› Issue (04): 271-274.

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Research progress of salivary histidine-rich cationic polypeptides

MIAO Yan, HAO Yu-qing.   

  1. Key. Laboratory of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China
  • Online:2007-07-20 Published:2007-07-20

Abstract:

Histidine-rich cationic polypeptides(HRPs) from human salivary glands have intim ate relationship with buccal health. Scholars did much research about histidine-rich cationic polypeptides since 80s of the 20th century, which showed that it had broad-spectrum antibacterial activity on oral fungi and cariogenic bacteria and periodontal pathogens. The article reviewed several aspects of HRPs, which included its kinds, origins, biological activities and m echanisms.

Key words: histidine-rich cationic polypeptides, biological activities, mechanism


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