Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (6): 641-642.doi: 10.3969/j.issn.1673-5749.2011.06.005

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Effects of Benzocaine compound gel on experimental toothache

Wei Baowei, Liu Buming, Chen Lili, LiuYuan, Yao Shuhan.   

  1. Guangxi Institute of Chinese Medical & Pharmaceutical Science, Nanning 530022, China
  • Received:2010-08-28 Revised:2011-08-29 Online:2011-11-20 Published:2011-11-20

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Abstract:

Objective To compare analgesic efficacy of the copied Benzocaine compound gel and its original product Orajel Mouth-Aid, an over the counter drug product made in USA. Methods Pain thresholds in dental pulp of rabbits, and in tail flick of rat model were used. Results By topical application, these two products exhibited dose-dependent analgesic actions in rabbits and rats. Conclusion These two products have analgesic efficacy with similar potency, and they are good for toothache.

Key words: Benzocaine, analgesic action, rabbit, rat


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