Int J Stomatol

Int J Stomatol ›› 2023, Vol. 50 ›› Issue (4): 388-394.doi: 10.7518/gjkq.2023053

• Cariology and Endodontics • Previous Articles     Next Articles

Effect and research progress on root canal infection management of regenerative endodontic procedure in immature permanent teeth

Wu Sijia(),Shu Chang,Wang Yang,Wang Yuan,Deng Shuli,Wang Huiming.()   

  1. Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China
  • Received:2022-09-02 Revised:2023-03-02 Online:2023-07-01 Published:2023-06-21
  • Contact: Huiming. Wang E-mail:22018586@zju.edu.cn;whmwhm@zju.edu.cn
  • Supported by:
    “Pioneer” and “Leading Goose” Research and Development Program in Zhe-jiang Province(2022C03060)

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Abstract:

Root canal infection management is a crucial step in regenerative endodontic procedure (REP), which include root canal irrigation and intracanal medicaments. Various factors, such as residual microorganisms or the cytotoxicity of root canal irrigants and drugs, affect the outcomes of REP. Scholars should search for an optimum infection management remedy to acquire sufficient antimicrobial efficacy and proper environment for tissue regeneration. The development of novel canal irrigants and irrigation techniques and the exploration of novel antibacterial scaffold can alleviate the adverse effects of REP. This article intends to discuss the influences of infection management on REP and elucidate its promising advances.

Key words: regenerative endodontic procedure, infection management, residual microorganism, cytotoxicity, antibacterial efficacy

CLC Number: 

  • R 781.33

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