Int J Stomatol ›› 2021, Vol. 48 ›› Issue (3): 334-340.doi: 10.7518/gjkq.2021021

• Reviews • Previous Articles     Next Articles

Advances in the loading methods of silver nanoparticles on the surface of titanium implants

Zhu Junjin(),Wang Jian.   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Prosthodon-tics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-08-09 Revised:2020-12-15 Online:2021-05-01 Published:2021-05-14
  • Supported by:
    National Natural Science Foundation of China(81970985)


Titanium dental implants are commonly used in oral implant repair. However, because they lack intrinsic antibacterial activity, these implants may lead to peri-implantitis and even implant surgery failure when bacterial infection occurs. Silver nanoparticles (Ag NPs), which are antibacterial agents with a wide antibacterial spectrum and low resistance, are commonly used to build antibacterial coatings on titanium implants and amplify their antimicrobial properties. Over the last decade, researchers have conducted numerous studies on the integration of Ag NPs into titanium implants to improve the antibacterial properties of the latter and avoid the cytotoxicity of the former by adjusting their synthesis methods or adding supportive ingredients. This paper reviews the current methods of loading Ag NPs on titanium implants and evaluates their advantages and disadvantages. Methods to increase Ag NPs and reduce their cytotoxicity are also summarized to provide new insights for future research.

Key words: titanium implant, silver nanoparticle, loading method, antibacterial activity, cytotoxicity

CLC Number: 

  • R783.1

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