Int J Stomatol

Int J Stomatol ›› 2021, Vol. 48 ›› Issue (4): 444-449.doi: 10.7518/gjkq.2021077

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Treatment of patients with negative cervical lymph nodes in maxillary squamous cell carcinoma

Li Shan(),Chen Linlin()   

  1. Dept. of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Oral Biomedicine in Jiangxi Province, Nanchang 330000, China
  • Received:2021-01-05 Revised:2021-04-07 Online:2021-07-01 Published:2021-06-30
  • Contact: Linlin Chen E-mail:11606019129@qq.com;oral_surgery@sina.com

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Abstract:

Maxillary squamous cell carcinoma (MSCC) with primary maxillary gingiva and hard palate is a relatively rare head and neck tumor. Considering the low incidence and the difficulty of case collection, only few studies focused on the clinical cervical lymph node-negative patients of MSCC. The related clinical treatment strategies are controversial, and a unified treatment guidance strategy remains lacking worldwide. The total rate of cervical lymph node metastasis in patients with MSCC is 21%-46.1%. The main influencing factors are tumor stage, degree of differentiation, location, neurovascular invasion, and bone infiltration. The 5-year survival rate of MSCC is 32%-70.8%. The main influencing factors are cervical lymph node metastasis, location, selective cervical lymph node dissection, and so on. MSCC has the risk of contralateral and bilateral metastases, the neck recurrence rate can reach 33%, and the success rate of salvage surgery is low. Selective neck dissection is recommended for patients with negative cervical lymph nodes in the T3/4 stage. A prospective, large-scale study is necessary to enhance the reliability of the results and provide powerful references for clinical treatment.

Key words: maxillary gingiva, hard palate, squamous cell carcinoma, cervical lymph node metastasis, cervical lymph node dissection

CLC Number: 

  • R730.56

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