Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (3): 364-366.doi: 10.3969/j.issn.1673-5749.2011.03.033

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Research progress on the osteogenesis effect of nel-like typeⅠgene and its application in bone tissue engineering

LIU Qi, LI Zu-bing．   

  1. The State Key Laboratory Breeding Base of Basic Science of Stomatology（Hubei- MOST） & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2010-10-22 Revised:2011-01-21 Online:2011-05-20 Published:2011-05-20

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Abstract:

Nel-like typeⅠgene is a novel gene which was found overexpressed in pre-fused areas of craniosynostosis patients. It was applied in bone tissue engineering as a new growth factor because of its biological functions on inducing osteoblast differentiaton and enhancing osteogenesis effect. This article will summary a review about the osteogenesis effect of nel-like typeⅠgene and its application in bone tissue engineering according what we have known.

Key words: nel-like typeⅠgene, growth factor, osteogenesis, tissue engineering


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