Int J Stomatol

Inter J Stomatol ›› 2016, Vol. 43 ›› Issue (4): 477-481.doi: 10.7518/gjkq.2016.04.022

Previous Articles     Next Articles

Roles of transforming growth factor-β superfamily in dentinogenesis

Chen Jinhuan, Sun Jianxun, Chen Xinmei   

  1. State Key Laboratory of Oral Diseases, Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Online:2016-07-01 Published:2016-07-01

RichHTML

3

PDF (PC)

562

Abstract: Transforming growth factor(TGF)-β superfamily is a group of essential growth factors involved in the regulation of cell proliferation, differentiation, and apoptosis. TGF-β, bone morphogenetic protein(BMP), growth differentiation factor(GDF), activin(ACT), inhibin and so on, share a set of similar spatial structures of proteins. Dentin, as the important supportive part of tooth structure, is formed with mineralized matrix, which secreted by odontoblasts. During dentin formation, TGF-β1 participates in the regulation of matrix formation, mineralization, and the odontoblasts arrangement; BMP involved in the adjustment of many transcription factors’ expression and mediated epithelialmesenchymal interaction in dentification; while GDF play roles in periodontal development and ACT regulates cell metabolism, inmmune response, damage repairment and so on. This article reviewed the advances on the roles of TGF-β superfamily in dentinogenesis.

Key words: transforming growth factor, dentin, dentification and development


TrendMD: 
[1] Lei Bin,Chen Ke. Classification and treatment of dentin dysplasia type Ⅰ [J]. Int J Stomatol, 2022, 49(3): 332-336.
[2] Li Yanfei,Zhang Xinchun. Research progress on the dentin bone repair material [J]. Int J Stomatol, 2022, 49(2): 197-203.
[3] Ding Jingyu,Tian Zilu,Wang Huimin,Zhu Xuanyan,Yang Yubin,Zhu Song. Advancement of immediate dentin sealing [J]. Int J Stomatol, 2022, 49(1): 121-124.
[4] Zhang Shan,Shen Shuping,Zhang Fang,Yang Weidong. Effect of photon-initiated photoacoustic streaming Er: YAG laser on the water loss of dentin and compressive strength of root [J]. Int J Stomatol, 2022, 49(1): 55-59.
[5] Xiong Menglin,Wu Long,Ma Li,Zhao Jin. Role of transforming growth factor-β2 in promoting the proliferation and differentiation of dental pulp stem cells [J]. Int J Stomatol, 2021, 48(6): 635-639.
[6] He Rong,Liu Xuejun,Zhou Yukun. Systematic review on the effect of photon-initiated photoacoustic streaming in endodontic irrigation [J]. Int J Stomatol, 2021, 48(6): 644-655.
[7] Zhao Binbin,Zhong Weijian,Ma Guowu. Research progress on dentin as bone transplantation material [J]. Int J Stomatol, 2021, 48(1): 82-89.
[8] Liu Enyan,Li Mingyun. Research progress on tea polyphenols in dentin adhesion [J]. Int J Stomatol, 2020, 47(6): 732-738.
[9] Zhu Mingjing,Zhang Qingbin. Comparative review of growth factors inducing 3D in vitro cartilage formation of mesenchymal stem cells [J]. Int J Stomatol, 2020, 47(3): 270-277.
[10] Jiaojiao Qin,Shan Jiao,Chengkun Wang. Advances in research on the effects of Er:YAG and Nd:YAG lasers on the bonding strength of the bonding surface between dentine and porcelain prosthesis [J]. Int J Stomatol, 2019, 46(3): 361-366.
[11] Xin Tan,Haiyang Yu. Application of simulated pulpal pressure in dentine-bonding research [J]. Inter J Stomatol, 2018, 45(6): 723-727.
[12] Jiangxue Tian,Longyi Mo,Xiaoyue Jia,Chengcheng Liu,Xin. Xu. Role of transforming growth factor-β in periodontitis [J]. Inter J Stomatol, 2018, 45(5): 553-559.
[13] Liao Wenting, Li Yan.. Influence of cysteine cathepsins on dentin bonding durability [J]. Inter J Stomatol, 2017, 44(3): 340-343.
[14] Gao Yuan, Xu Jialei, Yang Qian, Huang Dingming, Zhou Xuedong. Evaluation and removal strategies of the broken instruments in the root canal [J]. Inter J Stomatol, 2016, 43(3): 249-259.
[15] Xiong Hang, Xie Zhigang, Bao Jibo. Basic properties of the demineralization of dentin matrix and preparation [J]. Inter J Stomatol, 2016, 43(1): 90-.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .