国际口腔医学杂志

国际口腔医学杂志 ›› 2023, Vol. 50 ›› Issue (6): 679-685.doi: 10.7518/gjkq.2023107

• 综述 • 上一篇    下一篇

骨碎补在治疗口腔骨相关疾病的研究进展

黄元鸿(),彭显,周学东()   

  1. 口腔疾病防治全国重点实验室 国家口腔医学中心 国家口腔疾病临床医学研究中心四川大学华西口腔医院牙体牙髓病科 成都 610041
  • 收稿日期:2023-02-17 修回日期:2023-06-06 出版日期:2023-11-01 发布日期:2023-10-24
  • 通讯作者: 周学东
  • 作者简介:黄元鸿，医师，硕士，Email： huangyuanhung@163.com
  • 基金资助:
    国家重点研发计划(2016YFC1102701)

Progress in research into the effect of Rhizoma Drynariae on the treatment of bone-related diseases in the oral cavity

Huang Yuanhong(),Peng Xian,Zhou Xuedong.()   

  1. State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2023-02-17 Revised:2023-06-06 Online:2023-11-01 Published:2023-10-24
  • Contact: Xuedong. Zhou
  • Supported by:
    National Key Research and Development Plan(2016YFC1102701)

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摘要：

骨碎补是我国传统补肾强骨中药，主要含有黄酮类、三萜类、苯丙烷类、木脂素、酚酸等化合物，能有效的改善骨代谢、调控炎症因子，目前被广泛用于治疗骨折、骨关节炎等骨性疾病。口腔骨相关疾病与牙槽骨密度变化和炎症密切相关，近年越来越多的研究将骨碎补应用于口腔医学领域，包括促进牙周病骨愈合、加速正畸治疗牙移动和促进种植体表面骨结合等。本文就骨碎补的生物学功能及其治疗口腔骨相关疾病的研究进展作一综述，以期为后续研究和临床应用提供参考。

关键词: 骨碎补, 牙周炎, 牙移动, 种植体表面处理

Abstract:

Rhizoma Drynariae is a traditional Chinese medicine utilized to detoxify the kidney and strengthen the bones. It comprises a variety of compounds, including flavonoids, triterpenoids, phenylpropane, lignans, and phenolic acids, which effectively enhance bone metabolism and regulate inflammatory factors. It is currently utilized in the treatment of various bone-related disorders, such as bone fractures and knee osteoarthritis. In recent years, the effectiveness of Rhizoma Drynariae in treating bone-related diseases in the oral cavity has been assessed. The findings have shown that it can promote bone healing in periodontal diseases, accelerate tooth movement during orthodontic treatment, and promote the osseointegration of implant surfaces. This review aims to summarize the biological functions of Rhizoma Drynariae and recent progress in research into its use for the treatment of oral bone-related diseases, thus providing valuable reference for further study and clinical application.

Key words: Rhizoma Drynariae, periodontitis, tooth movement, implant surface treatment

中图分类号: 

  • R 781
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