国际口腔医学杂志

国际口腔医学杂志 ›› 2025, Vol. 52 ›› Issue (4): 526-533.doi: 10.7518/gjkq.2025070

• 综述 • 上一篇    下一篇

静电纺丝纳米纤维在颌面部组织修复中的应用

黄启航1(),王航2,王耀钟2,李德超1,2()   

  1. 1.山东第二医科大学口腔医学院 潍坊 261053
    2.青岛大学附属青岛市口腔医院口腔颌面外科 青岛 266001
  • 收稿日期:2024-10-21 修回日期:2025-04-02 出版日期:2025-07-01 发布日期:2025-06-20
  • 通讯作者: 李德超
  • 作者简介:黄启航，医师，硕士，Email：huangqihang1999@163.com
  • 基金资助:
    青岛市口腔疾病临床医学研究中心(22-3-7-lczx-7-nsh);山东省医药卫生口腔内科学重点学科项目（2024-2026）;青岛市医疗卫生重点学科建设项目（2022-2024）;山东省自然科学基金(ZR2024-QH484);青岛市自然科学基金(22-4-4-zrjj-120-jch)

Application of electrospun nanofibers in maxillofacial tissue repair

Qihang Huang1(),Hang Wang2,Yaozhong Wang2,Dechao Li1,2()   

  1. 1.School of Stomatology, Shandong Second Medical University, Weifang 261053, China
    2.Dept. of Oral and Maxillofacial Surgery, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao 266001, China
  • Received:2024-10-21 Revised:2025-04-02 Online:2025-07-01 Published:2025-06-20
  • Contact: Dechao Li
  • Supported by:
    Qingdao Clinical Research Center for Oral Diseases(22-3-7-lczx-7-nsh);Shandong Provincial Key Medical and Health Discipline of Oral Medicine (2024-2026);Qingdao Key Health Discipline Development Fund (2022-2024);Shandong Provincial Natural Science Foundation(ZR2024QH484);Qingdao Natural Science Foundation(22-4-4-zrjj-120-jch)

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摘要：

口腔疾病发病率较高，其治疗常需要新材料的应用。静电纺丝纳米纤维（ENF）凭借其独特的结构特征和优异的生物学功能，在口腔医学领域展现出广泛的应用价值，尤其在颌面部组织修复和牙齿再生等方面发挥着重要作用。对此，本文综述近年来ENF在口腔医学中的研究进展，简要概括其制备过程和特点，从口腔疾病中的临床应用进行分类阐述，并总结其在口腔疾病治疗中所面临的挑战及发展前景，旨在为口腔疾病的基础研究和临床应用提供参考。

关键词: 静电纺丝, 纳米纤维, 口腔疾病, 组织工程, 药物输送

Abstract:

The incidence of oral diseases is high, and its treatment often requires the application of new materials. Cha-racterized by their unique structural properties and exceptional biological functions, electrospinning nanofibers (ENFs) have shown significant application potential in oral medicine, particularly in maxillofacial tissue repair and tooth regeneration. This work reviews the research progress of ENFs in stomatology, summarizing their preparation process and characteristics, categorizing and elaborates their clinical applications in oral diseases, and outlining their challenges and development prospects in the treatment of oral diseases. The findings provide reference for basic research and clinical application of ENFs against oral diseases.

Key words: electrospinning, nanofiber, oral disease, tissue engineering, drug delivery

中图分类号: 

  • R62

图 1

主要静电纺丝装置及结构a：高压电源；b：喷丝头；c：注射器；d：泰勒锥；e：收集器；f：纤维形态。"

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