国际口腔医学杂志

国际口腔医学杂志 ›› 2021, Vol. 48 ›› Issue (2): 213-217.doi: 10.7518/gjkq.2021027

• 综述 • 上一篇    下一篇

Ehlers-Danlos综合征的口腔颌面部表现

刘帅1,2(),王宁祥1,3,林良缘4,吴娟1()   

  1. 1.南京大学医学院附属口腔医院·南京市口腔医院牙周病科 南京 210008
    2.南京市溧水区中医院口腔科 南京 211200
    3.南京市中医院·南京中医药大学附属医院口腔科 南京 210001
    4.南京医科大学附属儿童医院口腔科 南京 210029
  • 收稿日期:2020-06-21 修回日期:2020-10-31 出版日期:2021-03-01 发布日期:2021-03-17
  • 通讯作者: 吴娟
  • 作者简介:刘帅,硕士,Email： 1729624217@qq.com
  • 基金资助:
    南京市卫生科技发展项目(YKK18121);江苏省自然科学基金项目(BK20200149)

Oral and maxillofacial manifestations of Ehlers-Danlos syndrome

Liu Shuai1,2(),Wang Ningxiang1,3,Lin Liangyuan4,Wu Juan1()   

  1. 1. Dept. of Periodontology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China
    2. Dept. of Stomatology, Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing 211200, China
    3. Dept. of Stomatology, Nanjing Hospital of Chinese Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing 210001, China
    4. Dept. of Stomatology, Children,s Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2020-06-21 Revised:2020-10-31 Online:2021-03-01 Published:2021-03-17
  • Contact: Juan Wu
  • Supported by:
    Medical Science and Technology Development Foundation, Nanjing Department of Health(YKK18121);Natural Science Foundation of Jiangsu Province(BK20200149)

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摘要：

Ehlers-Danlos综合征是一组罕见的临床和遗传异质性的结缔组织疾病,表现为广泛的不同程度的皮肤、韧带、血管和内部器官结缔组织脆性增加,主要的临床特征包括皮肤脆弱,易擦伤,皮肤延展性过度和关节活动过度。尽管目前有关Ehlers-Danlos综合征口腔颌面部表现的临床数据并不多,但文献检索发现几乎Ehlers-Danlos综合征的所有分型都有口腔颌面部的改变,然而,这些改变常因为临床医生经验的不足而不被正确认识。本文将对Ehlers-Danlos综合征的口腔颌面部表现进行综述,以期为临床医生提供参考。

关键词: Ehlers-Danlos综合征, 口腔, 颌面部

Abstract:

Ehlers-Danlos syndromes (EDS) belong to a clinically and genetically heterogeneous group of rare hereditary disorders characterised by varying degrees of connective tissue fragility, which affects the skin, ligaments, blood vessels and internal organs. Principal clinical features include tissue fragility, skin extensibility and joint hypermobility. Published data on the oral and maxillofacial manifestations of EDS are limited, but literature search found that almost all types of EDS have oral and maxillofacial changes, and these changes are often not correctly recognised by clinicians. This article reviews the oral and maxillofacial manifestations of EDS to provide reference for clinicians.

Key words: Ehlers-Danlos syndrome, oral, maxillofacial

中图分类号: 

  • R782.2
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