关键词: 牙周病, 妊娠期糖尿病, C-反应蛋白

Abstract:

Objective To explore the correlation between periodontal disease and gestational diabetes mellitus(GDM) and determine whether or not periodontal disease influences the content of the serum C-reactive protein of GDM patients. Methods A case–control study was conducted consisting of 100 pregnant women with GDM and 100 pregnant women without GDM at 24 to 28 weeks of pregnancy. Periodontal parameters, including gingival index(GI), sulcus bleeding index(SBI), attachment level(AL), and probing depth(PD), were examined by a calibrated dentist. A student t-test was employed to analyze the difference between the two. Meanwhile, 30 cases of periodontitis and 30 cases of healthy periodontal situation were selected from the pregnant women with GDM. The content of C-reactive protein was examined and statistically analyzed. Results Aside from the periodontal probing depth, other periodontal health indexes significantly differed between the two groups(P<0.05). The serum C-reactive protein level of the pregnant women with both GDM and periodontitis was obviously higher than that the pregnant women with healthy periodontal situation(P<0.05). Conclusion Periodontal diseases correlate with gestational diabetes mellitus, and periodontitis may be a risk factor of gestational diabetes mellitus.

Key words: periodontal diseases, gestational diabetes mellitus, C-reactive protein